Rheumatology antibodies Flashcards Preview

3rd year medicine > Rheumatology antibodies > Flashcards

Flashcards in Rheumatology antibodies Deck (12)
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1
Q

ank spond

A

no antibody

‘ANCA associated maybe’

2
Q

ank spond HLA

A

B27

3
Q

antiphospholipid antibody

A

cariolipin and lupus anticoagulant

4
Q

behctes HLA

A

B51

5
Q

dermatomyositis

  • sensitive
  • specific
A

80% ANA

30% anti-tRNA (anti-Mi most specific. also antiJo)

6
Q

drug induced lupus

  • sensitive
  • specific
  • shitty 5% ones?
A

100% ANA
90% anti-histone

(ro and smith are 5%)

7
Q

PAN

A

pANCA

8
Q

RA

  • sensitive
  • specific
  • HLA
A

sensitive = 70% RF and CCP
specific = CCP
HLADR4/DR1

9
Q

sjogrens

  • sensitive
  • specific
  • other shitty one
A

sensitive = RF (100%)
specific = anti-Ro (70% - so is ANA)
shitty 30% = La

10
Q

which antibody causes neonatal heart block

A

anti-Ro

don’t (cant) cry about it

11
Q

SLE

  • sensitive
  • specific
  • disease monitirng
  • other shitty ones
A

sensitive = ANA
specific = smith
diease mnitirng = dsDNA

other shitties = ro, la, RF

12
Q

systemic sclerosis

  • sensitive
  • specif (liminted)
  • specific (diffuse)
A

ANA 90%
centromere
scl-70