Rickets

Question 1

Hypophos rickets values

Answer 1

Decreased P, normal Ca, PTH, vit D, increased Alk phos

Question 2

Hypophos rickets inheritence

Answer 2

XD

Question 3

Hypophos rickets mechanism

Answer 3

impaired renal abs phos

Question 4

Hypophos rickets tx

Answer 4

Vit D (calcitriol)

Question 5

Vit D def rickets values

Answer 5

Decreased vit D, Ca, phos; Increased alk phos, PTH

Question 6

Vit D def rickets inheritence

Answer 6

none - nutritional

Question 7

vit d def mechanism

Answer 7

Decreased vit D intake –> dec calc abs intestine –> inc PTH

Question 8

Vit D def rickets tx

Answer 8

vit D

Question 9

Type I vit D dep rickets values

Answer 9

Low Ca/phos; nomral 25 vit D, VERY LOW 1,25 vit D, increased Alk phos/PTH

Question 10

Type I vit D dep rickets inheritance

Answer 10

AR

Question 11

Type I vit D dep rickets mechanism

Answer 11

Defect in 25-hydroxyvitamin D 1 alpha hydroxylase —> can’t make activated vit D

Question 12

Type I vit D dep rickets tx

Answer 12

1-25 vit D

Question 13

Type II vit D dep rickets values

Answer 13

Low Ca/phos, VERY HIGH 1-25 vit D, high alk phos, PTH

Question 14

Type II vit D dep rickets inher

Answer 14

AR

Question 15

Type II vit D dep rickets mech

Answer 15

Defect 1-25 vit D rec

Question 16

Type II vit D dep rickets Tx

Answer 16

High doses 1-25