Ricketsia

Question 1

Ricketssia transmitted humans by

Answer 1

arthropods

Question 2

Ricketssia Characteristic

Answer 2

Intracellular
Arthropods hosts and vectors
Humans are accidental hosts 
**EXCEPT Ricket prowazekii**
Gram Neg
Do Not Stain Well
Slime Layer

Question 3

Ehrlichia

Answer 3

Ehrlichiosis

Question 4

Anaplasma

Answer 4

anaplasmoses

Question 5

Ricketsia Mech of Action

Answer 5

Attach to host,
induced phagcytosis
escape phagosome w/ phospholipase

Question 6

Vectors of Ricketsia

Answer 6

Ticks, Mites, Lice, fleas

Question 7

Ricketsia Pathogenesis

Answer 7

primarily endothelial cells
Necrotizing vasculitis,
EDEMA, hypoalbumemia
Typhus nodules in the brain

Question 8

Typhus Group (2)

Answer 8

prowazekii & typhi

Question 9

RMSF Group

Answer 9

Ricketsii and A lot of others

Question 10

Disease and distribution ricketsii

Answer 10

RMSF and Western Hemi

Question 11

Disease and distribution

Answer 11

Ricketssiapox & worldwide

Question 12

Disease and distribution

Answer 12

Epidemic Typhus Worldwide

Question 13

Disease and distribution

Answer 13

Murine Typhus World Wide

Question 14

Rickestia Ricketsii Epidemiology

Answer 14

Most Common
Rodent and Rabbitt reservoir
Ixodid Species Tick

Question 15

Rickestia Ricketsi Disease

Answer 15

2-14 day incubation
fever headache photophobia
RASH- macular wrists forearms, Petechial

Question 16

Rickestia Ricketsi Complications

Answer 16

Myocarditis, CNS dysfunction, renal, gangrene

Question 17

Ricketsia akari Epidemiology

Answer 17

House mouse, Norweigan Rat, black rat

Vector- House mouse mite

Question 18

Ricketssialpox

Answer 18

Incubation 7-10 Day
1 phase- Red papule, vesicular, dark eschar
2nd phase- 3-7 days skin lesion abrupt fever, severe headache
Rash 2-3 days

Question 19

Rickestsia prowazecki Typhus Epidemiology

Answer 19

Human Body Louse— VECTOR

No transovarial transmission

Question 20

Rickestsia prowazecki Disease

Answer 20

Incubation - 7-10 days
sudden onset
rash 4-7 days after fever and macular to petechial

Question 21

Ricketsia Prowazecki Complications

Answer 21

myocarditis, CNS dysfunction

Question 22

Rickestsia prowazecki Brill-Zinnser

Answer 22

Recurrent form

less sever, rarely fatal

Question 23

Rickestsia prowazecki Sylvatic epidemic typhus

Answer 23

Reservoid squirrel,

Vector Squirrel flea

Question 24

Rickestsia typhi

Answer 24

World Wide
Rats, mouse opposum, cat
Flea is vector
Transovarial occurs in fleas

Question 25

Rickestsia typhi Disease

Answer 25

Rash Absent

Question 26

Diagnosis Ricketsii

Answer 26

Presumptive Confirmatory •Serology • PCR

Question 27

Treatment Ricketsii

Answer 27

Doxycycline | Chloramphenicol: Pregnant

Question 28

Prevention Ricketsii

Answer 28

Control Reservoirs, | No vaccine availble any longer in U.S.

Question 29

Anaplasmatacae

Answer 29

Gram neg coccobacilli Less peptidoglycan Infect bone marrow derived cells Morulae looked like mulberries

Question 30

Vectors of Anaplasmatacae

Answer 30

Ticks mostly

Question 31

Ehrlichia Chaffeensis HME

Answer 31

Worlde Wide White Tail Deer, Dogs, Coyotes, Lone Star Tick American Dog tick

Question 32

Ehrlichia Chaffeensis HME Disease

Answer 32

Fever headache | Rash 5 days after, maculopapular, diffuse erythema

Question 33

Ehrlichia Chaffeensis HMEComplications

Answer 33

meningoencephalitis

Question 34

Anaplasma Phagocytophilum

Answer 34

World Wide Small and medium mammal reservoir Blacklegged western Blacklegged

Question 35

Anaplasma Phagocytophilum HGA Disease

Answer 35

7-14 day incubation | Rash is uncommon

Question 36

Anaplasma Phagocytophilum HGA Complications

Answer 36

``` ARDS Renal fail Toxic like Coagulopathy Polyneuropathy ```

Question 37

Diangosis of ehrlichia and anaplasma

Answer 37

Presumptive: Signs, history, Blood test, leukocytopenia Confirmatory: PCR whole bood *** IFA gold standard**

Question 38

ehrlichia and anaplasma Treatment

Answer 38

Doxycycline

Question 39

ehrlichia and anaplasma Prevention

Answer 39

No vaccines, tick vector