robbins

Question 1

No of genes in the genome

Answer 1

20K

Question 2

the percentage of genome coding genes

Answer 2

1.5P

Question 3

two most common forms of DNA variation

Answer 3

SNP and CNV

Question 4

two types of actin

Answer 4

G-actin (globular) and F-actin (filamentous)

Question 5

3 types of cytoskeleton components

Answer 5

actin microfilament (5-9 nm)
intermediate filament (10nm)
microtubules (25nm)

Question 6

which cytoskeletal component vary between cell types

Answer 6

intermediate filament

Question 7

vimentin is seen in mesenchymal cells eg.

Answer 7

fibroblasts or endothelium

Question 8

Desmin where and function

Answer 8

muscle, form a scaffold for actin and myosin interaction

Question 9

neurofilament and glial fibrillary acidic protein are

Answer 9

IF

Question 10

two types of CK

Answer 10

type I (acidic) and II (basic)

Question 11

CK is a - filament

Answer 11

IF

Question 12

three types of cell cell interactions

Answer 12

occluding, anchoring and communicating

Question 13

occluding cell junction aka

Answer 13

tight

Question 14

anchoring jn aka

Answer 14

desmosomes (hemidesmosomes if connecting to BM)

Question 15

communicating junction aka

Answer 15

gap

Question 16

diff between cadherin and integrin

Answer 16

cadherin desmosome and integrin hemidesmosome

Question 17

basement membrane is consists of

Answer 17

type IV collagen and laminin

Question 18

3 types of ECM components

Answer 18

structural proteins (collagen, elastin)
water hydrated gels (proteoglycan, hyaluronan)
adhesive glycoproteins (laminin, integrin)