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Flashcards in Rotation 3 pharm quiz Deck (52):
1

Dosage forms of atenolol

25 mg
50 mg
100 mg

2

Average daily dosages of atenolol

HTN: 50-100 mg daily
Angina pectoris: 50-200 mg daily

3

Common indications for atenolol

HTN
Angina pectoris

4

MOA of atenolol

Cardioselective beta-1 adrenergic receptor blocker which results in decreased HR and CO

5

Common SEs of atenolol

Drowsiness
Dizziness
Bradycardia
Hypotension
Fatigue

6

Renal or hepatic dosage adjustments for atenolol

Renal: CrCl 15-35: max dose 50 mg/day
CrCl <15: max dose 25 mg/day

7

BBW for atenolol

Withdrawn abruptly can cause acute tachycardia, HTN, and/or ischemia

8

Clinically significant drug interactions for atenolol

May decrease effect of clonidine
Verapamil increases toxicity effect of atenolol

9

Major counseling points of atenolol

May mask hypoglycemic sx in pt with DM.
Use caution while operating machinery or when mental alertness is required.
Rise slowly when standing up from sitting and lying position.
Do not abruptly d/c

10

Monitoring parameters of atenolol

BP
HR

11

Dosage forms of montelukast

Tablets 10 mg
Chewable tablets 4 mg, 5 mg
Granules 4 mg per foil packet

12

Average daily doses of montelukast

Adolescents and adults 15 yrs of age and older: one 10 mg tablet daily to be taken in the evening

13

Common indications for montelukast

Prophylaxis and chronic tx of asthma and adults and children 2 yrs of age and older.
Relief of seasonal rhinitis and perennial allergic rhinitis
Prevention of exercise-induced bronchoconstriction

14

MOA of montelukast

Selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor

15

Common AEs of montelukast

HA
Influenza
Cough
Abd pain
Dyspepsia
Dizziness

16

Clinically sig drug interactions of montelukast

Phenobarbital may increase metabolism
May decrease the metabolism of paclitaxel, rosiglitazone, and repaglinide

17

Major counseling points for montelukast

Indicated for chronic tx of asthma and should be taken regularly even when the pt is asymptomatic. Not intended to treat asthmatic attacks.
Singulair granules can be given either directly in the mouth or mixed with a spoonful of soft food

18

Monitoring parameters for montelukast

FEV1
Peak flow
Unusual changes in mood
Improvement in S/Sx of asthma

19

Dosage forms of clonazepam

Tablets 0.5 mg, 1 mg, 2 mg
Orally-disintegrating wafers 0.125 mg, 0.5 mg, 1 mg, 2 mg

20

Average daily dosages of of clonazepam

1.5-2 mg daily

21

Common indications for clonazepam

Lennox-Gastaut syndrome
Akinetic and myoclonic seizures
Absence seizures with succinimide failure
Panic disorder
GAD

22

MOA of clonazepam

Binds to and enhances activity of GABA receptors

23

Common AEs of clonazepam

Drowsiness
Ataxia
Fatigue
Dizziness

24

Clinically significant drug interactions of clonazepam

Increased CNS depression with EtOH and other CNS depressants
Caution in pts taking opioids d/t increased risk of sedation and resp depression

25

Major counseling points of clonazepam

May cause drowsiness
Avoid EtOH while taking this medication
May be habit-forming
Do not stop taking this med abruptly
Store in a cool dry place away from kids and sunlight
If a dose is missed, take it ASAP
If it is closer to the time of your next dose, skip the missed dose and return to nl dosing schedule- do not double doses

26

Monitoring parameters of clonazepam

Improvement in sx of anxiety
Misuse, abuse, decreased seizure activity

27

Dosage forms of penicillin

Powder: 125 mg/5 mL, 250 mg/5 mL
Tablet: 250 mg, 500 mg

28

Average daily dosages of penicillin

250- 1,000 mg/day

29

Common indications of penicillin

Various infections

30

MOA of penicillin

Inhibits cell wall mucopeptide biosynthesis

31

Common AEs of penicillin

Black tongue
Diarrhea
Vomiting

32

Renal or hepatic dose adjustments for penicillin

Consider dose adjustments with either renal or liver failure

33

Clinically sig drug interactions with penicillin

May result in an increased INR when taken by a warfarin pt

34

Major counseling points for penicillin

Take till empty
May effect the effectiveness of contraceptives

35

Monitoring parameters of penicillin

Improvement in S/Sx of infection, WBC

36

Dosage forms of Augmentin

PO suspension
Tablets
Tablets ER
Tablets chewable

37

Average daily doses of Augmentin

875 mg every 12 hrs

38

Common indications of Augmentin

Tx of OM, sinusitis, and infections caused by susceptible organisms involving the lower resp tract, skin and skin structure, and urinary tract

39

Common AEs of Augmentin

Diarrhea
GI upset
Vomiting

40

Renal or hepatic dose adjustments for Augmentin

Renal- CrCl 10-30: dose every 12 hrs, CrCl <10: dose every 24 hrs.
Do not use ER tablets in pts with hemodialysis

41

Major counseling points of Augmentin

Do not skip any doses
Take with food
Refrigerate suspension
If a rash develops contact physician
Ask for PCN allergy

42

Monitoring parameters of Augmentin

Improvement of S/sx of infection, WBC

43

Dosage forms of meloxicam

Tablets 7.5 mg, 15 mg
Oral suspension 7.5 mg/5 mL

44

Average daily dosages of meloxicam

7.5-15 mg daily

45

Common indications for meloxicam

OA
RA

46

MOA of meloxicam

Inhibits cylooxygenase resulting in a decreased biosynthesis of prostaglandins

47

Common AEs of meloxicam

Abd pain
Diarrhea
Dyspepsia
Flatulence
Nausea

48

Renal or hepatic dosage adjustments for meloxicam

Caution with sig renal and hepatic impairment

49

BBW for meloxicam

Use is contraindicated for tx of perioperative pain in the setting of CABG surgery.
Associated with an increased risk of adverse cardiovascular thrombotic events (MI, stroke)
Increased risk of GI irritation, inflammation, ulceration, bleeding, and perforation

50

Clinically sig drug interactions of meloxicam

Increase risk of bleeding in pts taking warfarin and other NSAIDs
Chronic use with NSAIDs and SSRIs/SNRIs increase risk of GI bleeds

51

Major counseling points of meloxicam

Avoid EtOH and concomittant use of other NSAIDs
May require up to 2 wks to see noticeable improvement in arthritic conditions.

52

Monitoring parameters of meloxicam

Improvement in inflammation/pain