RR - key associations Flashcards

(130 cards)

1
Q

Actinic (solar) keratosis

A

Precursor to squamous cell carcinoma

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2
Q

Acute gastric ulcer associated w/ CNS injury

A

Cushing’s ulcer (increased ICP stimulates vagal gastric secretion)

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3
Q

Acute gastric ulcer associated w/ severe burns

A

Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)

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4
Q

Alternating areas of transmural inflammation and normal colon

A

Skip lesions (Crohn’s)

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5
Q

Aneurysm, dissecting

A

Hypertension

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6
Q

Aortic aneurysm, abdominal and descending aorta

A

Atherosclerosis

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7
Q

Aortic aneurysm, arch

A

Tertiary syphilis, vasa vasorum destruction

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8
Q

Aortic aneurysm, ascending

A

Marfan’s (idiopathic cystic medial degeneration)

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9
Q

Atrophy of mammillary bodies

A

Wernicke’s encephalopathy (thiamine deficiency causing ataxia, ophthalmoplegia and confusion)

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10
Q

Autospenectomy (fibrosis and shrinkage)

A

Sickle cell

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11
Q

Bacteria associated with gastritis, peptic ulcer disease and stomach cancer

A

H. pylori

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12
Q

Bacterial meningitis (adults and elderly)

A

S. pneumo

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13
Q

Bacterial meningitis (newborns and kids)

A

Group B strep (newborns), S. pneumo/N. meningitidis (kids)

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14
Q

Bleeding disorder with GpIb deficiency

A

Bernard soulier syndrome (defect in platelet adhesion to vW factor)

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15
Q

Brain tumor (adults)

A

Supratentorial: metastasis > astrocytoma (including GBM) > meningioma > schwannoma

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16
Q

Brain tumor (kids)

A

Infratentorial: medulloblastoma (cerebellum)
Supratentorial: craniopharyngioma

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17
Q

Breast cancer

A

Infiltrating ductal carcinoma (in the US, 1 in 9 women will develop breast cancer)

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18
Q

Breast mass

A

Fibrocystic change, carcinoma (in postmenopausal women)

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19
Q

Breast tumor (benign)

A

Fibroadenoma

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20
Q

Cardiac primary tumor (kids)

A

Rhabdomyoma, often seen in tuberous sclerosis

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21
Q

Cardiac manifestation of lupus

A

Libman-Sacks endocarditis (nonbacterial, affecting both sides of mitral valve)

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22
Q

Cardiac tumor (adults)

A

Metastasis, primary myxoma (4:1 left to right atrium; “ball and valve”)

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23
Q

Cerebellar tonsillar herniation

A

Chiari malformation (often presents with progressive hydrocephalus or syringomyelia)

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24
Q

Chronic atrophic gastritis (autoimmune)

A

predisposes to gastric carcinoma (can also cause pernicious anemia)

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25
Clear cell adenocarcinoma of the vagina
DES exposure in utero
26
Compression fracture
Osteoporosis (type 1: postmenopausal; type 2: elderly man or woman)
27
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
28
Congenital cardiac anomaly
VSD
29
Congenital conjugated hyperbilirubinemia (black liver)
Dubin Johnson (inability of hepatocytes to secrete conjugated bilirubin into bile)
30
Constrictive pericarditis
Tuburculosis (developing world); SLE (developed world)
31
Coronary artery involved in thrombosis
LAD > RCA > LCA
32
Cretinism
Iodine deficit/hypothyroid
33
Cushing's syndrome
Iatrogenic cushings (from corticosteroid therapy) Adrenocortical adenoma ACTH secreting pituitary adenoma Paraneoplastic Cushing's (due to ACTH from other tumors)
34
Cyanosis (early, less common)
Tetralogy of Fallot, transposition, truncus (also TAPVR and tricuspid atresia)
35
Cyanosis (late, more common)
VSD, ASD, PDA
36
Death in CML
Blast crisis
37
Death in SLE
Lupus nephropathy
38
Dementia
Alzheimer's, multiple infarcts
39
Demyelinating disease in young women
MS
40
DIC
Severe sepsis, obstetric complications, cancer, burns, trauma, major surgery
41
Dietary deficit
Iron
42
Diverticulum in pharynx
Zenker's (diagnosed by barium swallow)
43
Ejection click
Aortic/pulmonic stenosis
44
Esophageal cancer
Squamous (worldwide), adeno (USA)
45
Food oisoning (exotoxin mediated)
S. auerus, B. cereus
46
Glomerulonephritis (adults)
Berger's IgA nephropathy
47
Gynecologic malignancy
Endometrial carcinoma (USA), cervical carcinoma (worldwide)
48
Heart murmur, congenital
Mitral valve prolapse
49
Heart valve in bacterial endocarditis
Mitral>aortic (rheumatic fever), tricuspid (IV drug abuse)
50
Helminth infection (US)
Enterobius vermicularis, ascaris lumbricoides
51
Hematoma-epidural
Rupture of middle meningeal artery (trauma, lentiform shaped)
52
Hematoma-subdural
Rupture of bridging veins (crescent shaped)
53
Hemochromatosis
Multiple transfusions or hereditary HFE mutation (can result in CHF, bronze diabetes, and increased risk of HCC)
54
Hepatocellular carcinoma
Cirrhotic liver (a/w hep B and C and alcoholism)
55
Hereditary bleeding disorder
von Willebrand disease
56
Hereditary harmless jaundice
Gilbert's syndrome (benign congenital unconjugated hyperbilirubinemia)
57
HLA-B27
Ankylosing spondylitis, Reiter's syndrome, ulcerative colitis, psoriasis
58
HLA-DR3 or DR4
DM type 1, rheumatoid arthritis, SLE
59
Holosystolic murmur
VSD, tricuspid regurg, mitral regurg
60
Hypercoagulability, endothelial damage, blood stasis
Virchow's triad (results in venous thrombosis)
61
Secondary HTN
Renal disease
62
Hypoparathyroidism
Accidental excision during thyroidectomy
63
Hypopituitarism
Pituitary adenoma (usually benign)
64
Infection secondary to blood transfusion
Hep C
65
Infections in chronic granulomatous disease
S. aureus, E. coli, Aspergillus (catalase positive)
66
Kidney stones
Calicum = radiopaque Struvite (ammonium) = radiopaque (formed by urease positive organisms such as proteus vulgaris or staph) Uric acid = radiolucent
67
Late cyanotic shunt (uncorrected LT to RT becomes RT to LT)
Eisenmenger's syndrome (caused by ASD, VSD, PDA; results in pulmonary hypertension/polycythemia)
68
Liver disease
Alcoholic cirrhosis
69
Lysosomal storage disease
Gaucher's
70
Male cancer
Prostate
71
Malignancy a/w noninfectious fever
Hodgkin's lymphoma
72
Malignancy (kids)
ALL, medulloblastoma (cerebellum)
73
Mental retardation
Down syndrome, fragile X
74
Metastases to bone
Prostate, breast > lung > thyroid, testes
75
Metastases to brain
Lung > breast > GU > osteosarcoma > melanoma > GI
76
Metastases to liver
Colon >> stomach, pancreas
77
Mitral valve stenosis
Rheumatic heart disease
78
Mixed (UMN and LMN) motor disease
ALS
79
Myocarditis
Coxsackie B
80
Nephrotic syndrome (adults)
FSGS
81
Nephrotic syndrome (kids)
Minimal change dz
82
Neuron migration failure
Kallmann syndrome (hypogonadotrophic hypogonadism and anosmia)
83
Nosocomial pneumonia
Klebs, E. coli, Pseudomonas
84
Obstruction of male urinary tract
BPH
85
Opening snap
Mitral stenosis
86
Opportunistic infection in AIDS
PCP
87
Osteomyelitis
S. aureus
88
Osteomyelitis in sickle cell
Salmonella
89
Osteomyelitis w/ IV drug use
Pseudomonas or S. aureus
90
Ovarian metastasis from gastric carcinoma or breast cancer
Krukenberg tumor (mucin-secreting signet ring cells)
91
Ovarian tumor (benign, bilateral)
Serous cystadenoma
92
Ovarian tumor (malignant)
serous cystadenocarcinoma
93
Pancreatitis (acute)
Gallstones, alcohol
94
Pancreatitis (chronic)
Alcohol (adults), CF (kids)
95
Patient age with ALL/CLL/AML/CML
ALL: child, CLL: adult > 60, AML: adult ~65, CML: adult 30-60
96
Pelvic inflammatory disease
Chlamydia trachomatis, N. gonorrhea
97
Philadelphia chromosome
t(9:22) bcr-abl CML (may sometomes be associated with ALL/AML)
98
Pituitary tumor
Prolactinoma, somatotrophic "acidophilic" adenoma
99
Primary amenorrhea
Turner's
100
Primary bone tumor (adults)
Multiple myeloma
101
Primary hyperaldosteronism
Adenoma of adrenal cortex
102
Primary liver cancer
HCC (chronic hepatitis, cirrhosis, hemochromatosis, a1 anti trypsin deficiency)
103
Pulmonary hypertension
COPD
104
Recurrent inflammation/thrombosis of small/medium vessels in extremities
Buerger's disease (strong a/w tobacco)
105
Renal tumor
Renal cell carcinoma: a/w von Hippel Lindau and smoking; paraneoplastic syndromes include EPO, renin, PTH, ACTH
106
RT heart failure due to pulmonary cause
Cor pulmonale
107
S3 (protodiastolic gallop)
Increased ventricular filling (left to right shunt, mitral regurg, LV failure/CHF)
108
S4 (presystolic gallop)
Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)
109
Secondary hyperparathyroidism
Hypocalcemia of chronic kindney disease
110
Sexually transmitted disease
Chlamydia (usually coinfected with gonorrhea)
111
SIADH
Small cell lung carcinoma
112
Site of diverticula
Sigmoid colon
113
Sites of atherosclerosis
Abdominal aorta > coronary artery > popliteal artery > carotid artery
114
Stomach cancer
Adenocarcinoma
115
Stomach ulcerations and high gastrin levels
Zollinger-Ellison syndrome (gastrinoma of duodenum or pancreas)
116
t(14:18)
Follicular lymphomas (bcl-2 activation)
117
t(8:14)
Burkitt's lymphoma (c-myc activation)
118
t(9:22)
Philadelphia chromosom CML (bcr-abl fusion)
119
Temporal arteritis
Risk of ipsilateral blindness due to thrombosis of ophthalmic artery; a/w polymyalgia rheumatica
120
Testicular tumor
Seminoma
121
Thyroid cancer
Papillary carcinoma
122
Tumor in women
Leiomyoma (estrogen dependent, not precancerous)
123
Tumor of infancy
Hemangioma (usually regresses spontaneously by childhood)
124
Tumor of the adrenal medulla (adults)
Pheo (usually benign)
125
Tumor of adrenal medulla in kids
Neuroblastoma (malignant)
126
Type of Hodgkin's
Nodular sclerosing (vs. mixed cellularity, lymphocytic predominance, lymphocytic depletion)
127
Type of non-Hodgkin's
Diffuse large B cell
128
UTI
E. coli, Staph saprophyticus (young women)
129
Viral encephalitis affecting temporal lobe
HSV-1
130
Vitamin deficiency (USA)
Folate (pregnant women at high risk; body stores only 3 to 4 month supply; prevents neural tube defects)