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RSI Drugs Flashcards

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1
Q

Generic name for Versed

A

midazolam

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2
Q

Common name for midazolam

A

Versed

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3
Q

midazolam (Versed) Class

A

CNS depressant, benzodiazepine, anticonvulsant, anxiolytic

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4
Q

midazolam (Versed) Indications

A

seizures, chemical restraint for psychotic episodes

sedation for RSI

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5
Q

midazolam (Versed) MOA

A

supresses seizures, reduces anxiety, relaxes skeletal muscles through short-term CNS depression

produces amnesia (RSI)

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6
Q

midazolam (Versed) Side Effects

A

respiratory depression, apnea, bradycardia, hypotension, drowsiness, nausea, vomiting, laryngospasms, bronchospasm, tachycardia, PVCs, blurred vision, headache, cough, altered loc, pain during injection, phlebitis

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7
Q

midazolam (Versed) Contraindications

A

allergic, hypotension, shock, acute narrow angle glaucoma, head injury, drug/ETOH on board

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8
Q

midazolam (Versed) Precautions

A

use flumazenil (Romazicon) to treat overdose unless convulsing or hx of seizures,support pt’s airway s/p severe respiratory depression, use caution when administering elderly/COPD/hepatic/renal pts, use caution when giving during MI s/p cardiogenic shock

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9
Q

midazolam (Versed) Interactions

A

using with CNS depressants or other benzos will potentiate (drastically increase) the effects

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10
Q

midazolam (Versed) Administration

A

Routes: SLOW IVP (1mg/min),IO, IM, IN

Onset: 1-3 min

Duration: 2-6 hrs (consider redose after 30 min)

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11
Q

midazolam (Versed) Dosage

A

0.01-0.05 mg/kg IV
(MAX 5mg per dose)

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12
Q

Generic name for Amidate

A

etomidate

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13
Q

Common name for etomidate

A

Amidate

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14
Q

etomidate (Amidate) Class

A

CNS depressant, anesthetic, sedative, hypnotic

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15
Q

etomidate (Amidate) Indications

A

cardioversion or pacing

sedation (RSI)

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16
Q

etomidate (Amidate) MOA

A

sedation, anesthesia, amnesia; short acting non-barbiturate

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17
Q

etomidate (Amidate) Side Effects

A

nausea, vomiting, hypotension, hypoventilation, apnea, dysrhythmias, laryngospasms

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18
Q

etomidate (Amidate) Contraindications

A

allergic, status asthmaticus, HIV/AIDS/transplants/chemo pts, adrenal issue pts (i.e. Addison’s Disease, suppresses the adrenal gland’s production of steroids)

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19
Q

etomidate (Amidate) Precautions

A

respiratory depression

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20
Q

etomidate (Amidate) Interactions

A

use with verapamil may increase CNS depression and anesthesia; use with diuretics, calcium channel blockers, and antihypertensives may increase hypotension; use with other CNS depressants increases sedative effects

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21
Q

etomidate (Amidate) Administration

A

Routes: SLOW IVP, IO

Onset: immediate

Duration: 3-5 minutes

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22
Q

etomidate (Amidate) Dosage

A

0.2-0.6 mg/kg SLOW IVP (over 1 min)

Common RSI dose: 20mg

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23
Q

Generic name for Ketalar

A

ketamine

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24
Q

Common name for ketamine

A

Ketalar

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25
ketamine (Ketalar) Class
CNS depressant, anesthetic, sedative, dissociative hypnotic, analgesic
26
ketamine (Ketalar) Indications
pain management, chemical restraint, epileptic seizures, bronchodilator (COPD) sedation prior to RSI (or other painful procedures, i.e. cardioversion, pacing)
27
ketamine (Ketalar) MOA
non-barbituate CNS depressant that causes profound anesthesia and analgesia without causing skeletal muscle relaxation or respiratory depression in proper doses, dissociative agent that allows pts to be awake but distant from pain
28
ketamine (Ketalar) Side Effects
severe hallucinations, tachycardia, hypertension, hypersecretions, laryngospasm, drowsiness, nausea, vomiting
29
ketamine (Ketalar) Contraindications
allergic, head injury
30
ketamine (Ketalar) Precautions
ETOH on board, be prepared to handle severe hallucinations and psychosis when waking up
31
ketamine (Ketalar) Interactions
CNS depressants increase the effects of ketamine
32
ketamine (Ketalar) Administration
Routes: IV, IO, IM, IN Onset: 3-5 min Duration: 20-30 min
33
ketamine (Ketalar) Dosage
Analgesia: 0.3-0.5 mg/kg IV Behavior Management (restraint): 3mg/kg IM OR 1mg/kg IV RSI Sedation: 1-2mg/kg IV or 4mg/kg IM
34
Generic name for Anectine
succinylcholine
35
Common name for succinylcholine
Anectine
36
succinylcholine (Anectine) Class
depolarizing neuromuscular blocker, paralytic
37
succinylcholine (Anectine) Indications
RSI
38
succinylcholine (Anectine) MOA
binds with cholinergic receptor sites at neuromuscular endplate and causes depolarization of skeletal muscle cells (fasciculations) followed by paralysis due to the continued binding of the receptor site and blockage of acetylcholine
39
succinylcholine (Anectine) Side Effects
increased intraocular pressure, muscle stiffness or pain, hypotension, bradycardia, tachycardia, prolonged respiratory depression, bronchospasm, dysrhythmia, flushing of skin, hyperkalemia, malignant hyperthermia
40
succinylcholine (Anectine) Contraindications
hypersensitivity, acute narrow angle glaucoma or penetrating eye injury (increases intraocular pressure), malignant hyperthermia, myasthenia gravis or other neuromuscular diseases
41
succinylcholine (Anectine) Precautions
use caution in patients with burns, crush injuries, fractures, cardiac disease, respiratory disease, the elderly and children less than two years old
42
succinylcholine (Anectine) Interactions
diazepam (Valium) may shorten duration; theophylline and cardiac glycosides may cause dysrhythmias; narcotics and oxytocin may increase neuromuscular blockade
43
succinylcholine (Anectine) Administration
Route: IV, IO Onset: 1 min Duration: 6-10 min
44
succinylcholine (Anectine) Dosage
1-1.5 mg/kg IV
45
What is the Generic name for Zemuron
rocuronium
46
What is the common name for rocuronium
Zemuron
47
rocuronium (Zemuron) Class
non-depolarizing neuromuscular blocker, paralytic
48
rocuronium (Zemuron) Indications
RSI, skeletal muscle relaxation
49
rocuronium (Zemuron) MOA
competes for and binds with cholinergic receptor sites to inhibit neuromuscular transmission and cause paralysis
50
rocuronium (Zemuron) Side Effects
hypotension, hypertension, respiratory depression, apnea, tachycardia, bronchospasms, urticaria, nausea, vomiting
51
rocuronium (Zemuron) Contraindications
hypersensitivity
52
rocuronium (Zemuron) Precautions
use caution in patients with hepatic or renal failure; will cause respiratory depression, be prepared to aggressively ventilate and intubate; does not cause sedation or analgesia, administer a benzodiazepine or narcotic prior to giving rocuronium to create sedation; use a combination of physostigmine, edrophonium and/or neostigmine to reverse the effects of rocuronium
53
rocuronium (Zemuron) Interactions
use with succinylcholine (Anectine), anesthetics, lidocaine (Xylocaine), quinidine, procainamide (Pronestyl, Procan), beta blockers, diuretics and magnesium can prolong paralysis and respiratory depression
54
rocuronium (Zemuron) Administration
Route: IV, IO, IVPB Onset: 30-60 sec Duration: 30-60 min
55
rocuronium (Zemuron) Dosage
IV: 0.6-1.2 mg/kg (1mg/kg) IVPB: 0.1-0.2 mg/kg/min
56
What is the Generic name for Norcuron
vecuronium
57
What is the common name for vecuronium
Norcuron
58
vecuronium (Norcuron) Class
non-depolarizing neuromuscular blocker, paralytic
59
vecuronium (Norcuron) Indications
RSI
60
vecuronium (Norcuron) MOA
competes for and binds with cholinergic receptor sites to inhibit neuromuscular transmission and cause paralysis
61
vecuronium (Norcuron) Side Effects
respiratory depression, apnea, prolonged paralysis
62
vecuronium (Norcuron) Contraindications
hypersensitivity, myasthenia gravis and other neuromuscular diseases
63
vecuronium (Norcuron) Precautions
use caution in patients with renal failure, pregnant women on magnesium sulfate and children younger than two years old; vecuronium does not cause sedation or analgesia; administer a benzodiazepine or narcotic prior to giving vecuronium to create sedation
64
vecuronium (Norcuron) Interactions
use with narcotics or other neuromuscular blockers can prolong paralysis and respiratory depression; vecuronium is typically refrigerated
65
vecuronium (Norcuron) Administration
Route: IV Onset: 1 min Duration: 30 min
66
vecuronium (Norcuron) Dosage
0.1 mg/kg IV

Paramedic (1 decks)

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