RSI Pharmacology Flashcards

1
Q

succinylcholine (trade name)

A

Anectine

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2
Q

Anectine (generic name)

A

succinylcholine

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3
Q

rocuronium (trade name)

A

Zemuron

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4
Q

Zemuron (generic name)

A

rocuronium

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5
Q

vecuronium (trade name)

A

Norcuron

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6
Q

Norcuron (generic name)

A

vecuronium

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7
Q

midazolam (trade name)

A

Versed

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8
Q

Versed (generic name)

A

midazolam

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9
Q

etomidate (trade name)

A

Amidate

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10
Q

Amidate (generic name)

A

etomidate

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11
Q

ketamine (trade name)

A

Ketalar

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12
Q

Ketalar (generic name)

A

ketamine

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13
Q

Succinylcholine classification

A

Depolarizing neuromuscular blocker

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14
Q

Succinylcholine action

A

Competes with the ACh receptor of the muscle cell, resulting in depolarization

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15
Q

Succinylcholine indications

A

To induce neuromuscular blockade for the facilitation of ET intubation

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16
Q

Succinylcholine contraindications

A

Malignant hyperthermia, burns, trauma, known hyperkalemia

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17
Q

Succinylcholine dosage (adult)

A

0.6 mg/kg IV
0.3-1.1 mg/kg IO
3-4 mg/kg IM (max dose 150 mg)

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18
Q

Succinylcholine dosage (pediatrics)

A

1 mg/kg IV/IO (adolescents)
2 mg/kg IV/IO (small children)
3-4 mg/kg IM (max dose 150 mg)

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19
Q

Rocuronium classification

A

Nondepolarizing neuromuscular blocker

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20
Q

Rocuronium action

A

Antagonizes ACh at the receptor, producing muscle paralysis

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21
Q

Rocuronium indications

A

To induce neuromuscular blockade for the facilitation of ET intubation

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22
Q

Rocuronium contraindications

A

Known sensitivity to bromides. Use with caution in heart/liver disease

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23
Q

Rocuronium dosage (adult)

A

06-1.2 mg/kg IV/IO

24
Q

Rocuronium dosage (pediatric)

A

0.9-1.2 mg/kg IV/IO (>3 months)

25
Q

Succinylcholine onset and duration

A

Onset is 0.5-1 minute IV, 2-3 minutes IM

Duration is approximately 5 minutes

26
Q

Succinylcholine considerations

A
Can produce profound bradycardia in pediatrics
Pregnancy class C
27
Q

Rocuronium onset and duration

A

Onset is 0.5-2 minutes

Duration is approximately 30 minuntes

28
Q

Rocuronium considerations

A

Pregnancy class B

29
Q

Vecuronium classification

A

Nondepolarizing neuromuscular blocker

30
Q

Vecuronium action

A

Antagonizes ACh at the receptor, producing skeletal muscle paralysis

31
Q

Vecuronium indications

A

To induce neuromuscular blockade for the facilitation of ET intubation

32
Q

Vecuronium contraindications

A

Known sensitivity to bromides. Use with caution in heart/liver disease

33
Q

Vecuronium dosage (adult)

A

0.08-0.1 mg/kg IV/IO

34
Q

Vecuronium dose (pediatrics)

A

0.1-0.15 mg/kg IV/IO

35
Q

Vecuronium onset and duration

A

Onset is 1-3 minutes

Duration is 25-40 minutes

36
Q

Vecuronium considerations

A

Pregnancy class C

37
Q

Midazolam classification

A

Benzodiazepine, Schedule C-IV

38
Q

Midazolam action

A

Enhances GABA, producing short-acting CNS depression

39
Q

Midazolam indications

A

Sedation, anxiety, skeletal muscle relaxation

40
Q

Midazolam contraindications

A

Acute-angle glaucoma, pregnant women, known sensitivity

41
Q

Midazolam dosage (adult)

A

1-2.5 mg IV/IO, max of 5
Less may be needed for older, more ill patients (generally max of 3)
0.02-0.1 mg/kg/hr for continuous infusion

42
Q

Midazolam dosage (pediatrics)

A

12-16 yo: same as adults, max 10mg
6-12 yo: 0.025-0.05 mg/kg IV/IO, max 0.4 mg/kg not to exceed 10mg
6mo-5yo: 0.05-0.1 mg/kg IV/IO, max 0.6mg/kg not to exceed 6 mg
<6mo: 0.05-0.1 mg/kg IV/IO

43
Q

Midazolam considerations

A

Pregnancy class D

44
Q

Etomidate classification

A

Hypnotic, anesthesia induction agent

45
Q

Etomidate action

A

GABA-like effects

46
Q

Etomidate indications

A

Induction for RSI and pharmacologic-assisted intubation; induction of anesthesia

47
Q

Etomidate contraindications

A

Known sensitivity. Use in pregnancy only if the benefits outweigh the risks. Do not use during labor or in nursing mothers

48
Q

Etomidate dosage (adult)

A

0.2-0.6 mg/kg slow IV

49
Q

Etomidate dosage (pediatric)

A

> 10 yo: 0.2-0.6 mg/kg slow IV

<10 yo: safety has not been established

50
Q

Etomidate considerations

A

Pregnancy class C. Only use if benefits outweigh risks

51
Q

Ketamine classification

A

General anesthetic, analgesic, sedative

52
Q

Ketamine action

A

Produces a state of anesthesia while maintaining airway reflexes and stable vitals

53
Q

Ketamine indications

A

Pain and as anesthesia for procedures of short duration

54
Q

Ketamine contraindications

A

Patients in whom a significant elevation in BP would be hazardous (HTN, stroke, head trauma, MI), caution in patients with increased ICP and patients with hypovolemia, dehydration, or cardiac disease

55
Q

Ketamine dosage (adult)

A

1-4.5 mg/kg slow IV/IO

6.5-13 mg/kg IM

56
Q

Ketamine dosage (pediatric)

A

0.5-2 mg/kg slow IV/IO

4-5 mg/kg IM

57
Q

Ketamine considerations

A

Pregnancy class C