Flashcards in S18 Cardio biochemistry Lipoproteins Deck (13):
components of lipid profile
LDL cholesterol calculation
Total cholesterol- HDL cholesterol- Griglycerides/5
intermediate density lipoproteins.
return endogenous lipids to liver
ApoA's are found in
chylomicrons and HDL
ApoC are associated
with all classes
ApoE is associated with
older remnant lipoproteins and all classes
LDL over 150 mg/dl
Total Cholesterol above 240 mg/dl
Niemann-pick type C disease
Cholesterol not released fro lysosome
cells die (nerve cells), early death
HDL is taken up by the
SR-B1 receptor (on many cells) or the HDL receptor (mainly liver)
HDL requires two enzymes
LCAT (lecithin cholesterol acyl-transferase) helper enzyme esterifies cholesterol, and secures cholesterol for transport.
CETP exchanges cholesterol esters for triglycerices between HDL and VLDL.