(s3-7) Mass Transport Flashcards
(73 cards)
Haemoglobin
What is haemoglobin, and what is its role of it in the transport of oxygen?
Haemoglobin is a protein with a quaternary structure found in red blood cells.
Haemoglobin binds to oxygen and carries it in the blood from the lungs to tissues where it’s needed. It then releases the oxygen for cells to use.
Haemoglobin
What does the cooperative nature of oxygen binding mean?
The cooperative nature of oxygen binding means that the binding of the first oxygen molecule to haemoglobin makes it easier for subsequent oxygen molecules to bind.
Haemoglobin
Compare the partial pressures of oxygen in the lungs and in respiring tissues, including reference to haemoglobin binding to or releasing oxygen.
In the lungs, the partial pressure of oxygen is high, so haemoglobin binds to oxygen.
In respiring tissues, the partial pressure of oxygen is low, so haemoglobin releases oxygen.
Haemoglobin
What is the Bohr effect?
The Bohr effect, or Bohr shift, refers to the rightward shift in the oxygen dissociation curve in response to increased carbon dioxide concentration.
Higher carbon dioxide levels make haemoglobin release oxygen more readily, enhancing oxygen unloading when it’s needed.
Haemoglobin
What is the oxygen dissociation curve?
The oxygen dissociation curve is a graph showing how the saturation of haemoglobin with oxygen changes when the partial pressure of oxygen changes.
It is sometimes called the oxyhaemoglobin dissociation curve.
Haemoglobin
What is the significance of diffusion affinities for oxygen in fetal and adult haemoglobin?
Fetal haemoglobin has a higher affinity for oxygen than adult haemoglobin, allowing it to draw oxygen from the mother’s blood supply.
Circulatory System
Name the major blood vessels that enter and leave the kidneys and state their functions.
Renal artery - transports oxygenated blood to the kidneys
Renal vein - transports deoxygenaed blood away from the kidneys
Circulatory System
Name the major vessels that enter and leave the heart, what they transport, and where transport it to.
- Pulmonary veins - transports oxygenated blood from the lungs to the heart
- Pulmonary arteries - transports deoxygenated blood from the heart to the lungs
- Aorta - transports oxygenated blood from the heart to the body
- Vena cava - transports deoxygenated blood from the body to the heart
Circulatory System
What do we mean by systemic circulation and pulmonary circulation?
- Systemic circulation transports blood between the heart and the body cells
- Pulmonary circulation transports blood between the heart and the lungs
Circulatory System
What factors increase an organism’s need for a circulatory system with a pumping mechanism?
- Large size
- Low surface area to volume ratio
- High metabolic activity
Circulatory System
Why do large, complex organisms require transport systems?
Large organisms tend to have a small surface area to volume ratio, so diffusion is too slow to transport required materials.
Heart Structure
What are the key functions of the atria and ventricles in the mammalian heart?
Atria recieves blood returning to the heart, and pump it into the ventricles:
1. The right atrium recieves deoxygenated blood from the body
2. The left atrium recieves oxygenated blood from the lungs
Ventricles pump blood out of the heart:
3. The right ventricle pumps deoxygenated blood from the lungs.
4. The left ventricle pumps oxygenated blood to the body.
Heart Structure
Compare the structure of the atria and ventricles in a mammalian heart, and explain these differences.
Atria are smaller and have thinner walls as they only need to pump blood to the ventricles.
Ventricles have thicker muscular walls to pump blood out of the heart to the lungs and rest of the body, which requires more force.
Heart Structure
Compare the structure and function of the left and right ventricles in the mammalian heart, and explain these differences.
The left ventricle has a thicker muscular wall as it pumps oxygenated blood to the entire body, requiring more force.
The right ventricle has a thinner wall as it only pumps deoxygenated blood to the lungs, which are close by.
Heart Structure
Why does blood need to return to the heart after being oxygenated by the lungs, before being transported to the rest of the body?
Blood needs to return to the heart because, after the reduction in pressure that occurs when blood travels through the pulmonary capillaries, the pressure needs to increase again.
Blood needs to be pumped to the rest of the body under high pressure to ensusre efficient delivery of oxygen and nutrients to all cells.
Heart Structure
State the names of the valves between the atria and ventricles on each side of the heart.
Valve between the right atrium and right ventricle: tricuspid valve or right atrioventricular valve.
Valve between the left atrium and left ventricles: bicuspid valve or left atrioventricular valve.
Heart Structure
What is the function of the valves between the atria and the ventricles?
The valves between the atria and ventricles ensure one-way flow of blood from the atria to the ventricles, preventing backflow when the ventricles contract.
Heart Structure
Which blood vessels are connected to the left and right atria, and where do they transport blood from/to?
- The right atrium is connected to the vena cava - transports deoxygenated blood from the body into the heart
- The left atrium is connected to the pulmonary vein - transports oxygenated blood from the lungs into the heart
Heart Structure
Which blood vessels are connected to the left and right ventricles, and where do they transport blood from/to?
- The right ventricle is connected to the pulmonary artery - transports deoxygenated blood from the heart to the lungs
- The left ventricle is connected to the aorta - transports oxygenated blood from the heart to the body
Heart Structure
What is the septum, and what is its function?
The septum is a muscular wall that seperates the left and right sides of the heart.
The septum prevents oxygenated and deoxygenated blood from mixing.
Heart Structure
What are the semilunar valves, and what is their function?
The semilunar valves are located between each of the ventricles and the pulmonary artery and aorta, respectively.
The semilunar valves prevent backflow of blood into the heart after it has been pumped out.
Cardiac Cycle
What is diastole
Diastole is the phase of the cardiac cycle where the heart relaxes.
Blood flows into the atria through the pulmonary vein and the vena cava, pushing open the atrioventricular valves and filling the ventricles.
Cardiac Cycle
What happens during atrial systole?
During atrial systole, the atrial walls contract, forcing the remaining blood into the ventricles.
Throughout this stage, the muscle of the ventricle walls remains relaxed.
Cardiac Cycle
What happens during ventricular sytole?
During ventricular systole, the ventricular walls contract simultaneously, increasing blood pressure within them.
This closes the atrioventricular valves and forces blood into the aorta and pulmonary artery.