S6 Flashcards

(25 cards)

1
Q

Mr X is a 53-year-old patient with hypertension. He was started on an antihypertensive medication and has recently developed a persistent dry cough.
Azilsartan medoxomil
Bendroflumethiazide
Captopril
Eprosartan
Furosemide
Indapamide
Spironolactone
Telmisartan

A

Captopril

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2
Q

Mrs Q is a 49-year-old patient with resistant hypertension. She has noticed unusual vaginal bleeding.
Azilsartan medoxomil
Bendroflumethiazide
Captopril
Eprosartan
Furosemide
Indapamide
Spironolactone
Telmisartan

A

Spironolactone - menstrual disturbances such as post menopausal bleeding are a side effect of spironolactone

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3
Q

Mr A is a 45-year-old patient with hypertension. He has difficulty sleeping.
Azilsartan medoxomil
Bendroflumethiazide
Captopril
Eprosartan
Furosemide
Indapamide
Spironolactone
Telmisartan

A

Insomnia is a side effect of captopril

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4
Q

A patient presents with poor renal function, upon calculating her renal function it is determined that her eGFR is currently 27 mL/minute. Which of the following drugs would be ineffective for use in the patient?

Amiodarone

Bendroflumethiazide

Colestyramine

Levomemprazine

Piperacillin with tazobactam

Pseudoephedrine

Sodium hyaluronate 0.1% eye drops

Ursodeoxycholic acid

A

Thiazide and related diuretics are ineffective if eGFR is less than 30ml/min and should be avoided

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5
Q

A patient with a dysfunctioning thyroid hormone should not be initiated on this medication due to the ability of the medication to accentuate thyroid problems.

Amiodarone

Bendroflumethiazide

Colestyramine

Levomemprazine

Piperacillin with tazobactam

Pseudoephedrine

Sodium hyaluronate 0.1% eye drops

Ursodeoxycholic acid

A

Amiodarone

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6
Q

You are reviewing a patient with sinoatrial block, which drug is contraindicated for use in the patient.

Amiodarone

Bendroflumethiazide

Colestyramine

Levomemprazine

Piperacillin with tazobactam

Pseudoephedrine

Sodium hyaluronate 0.1% eye drops

Ursodeoxycholic acid

A

Amioadarone is contraindicated in those with sinoatrial block

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7
Q

You receive a phone call from a GP regarding the suitability of medicines in a patient suffering with complete biliary obstruction. Which one of the listed drugs is contraindicated in a patient suffering with complete biliary obstruction?

Amiodarone

Bendroflumethiazide

Colestyramine

Levomemprazine

Piperacillin with tazobactam

Pseudoephedrine

Sodium hyaluronate 0.1% eye drops

Ursodeoxycholic acid

A

Colestyramine is contraindicated in complete biliary obstruction as it is not likely to be effective

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8
Q

On a ward round you discover a patient has been admitted with acute inflammation of the gall bladder. Which medication is contraindicated in this patient?

Amiodarone

Bendroflumethiazide

Colestyramine

Levomemprazine

Piperacillin with tazobactam

Pseudoephedrine

Sodium hyaluronate 0.1% eye drops

Ursodeoxycholic acid

A

Ursodeoxycholic acid is contraindicated in patients with acute gall bladder inflammation

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9
Q

A doctor contacts you asking you to suggest a drug to treat a patient who has contracted meningococcal disease. Which drug would be suitable to be given via intravenous infusion in this patient.

Aztreonam

Benzylpenicillin sodium

Flucloxacillin

Linezolid

Metronidazole

Phenoxymethylpenicillin

Timethoprim

Tinidazole

A

Benzylpenicillin is indicated for use in meningococcal disease at a dose of 2.4 grams every 4 hours via slow intravenous injection or by intravenous infusion

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10
Q

This antibiotic is completely contraindicated with alcohol due to a disulfiram-like reaction if taken together.

Aztreonam

Benzylpenicillin sodium

Flucloxacillin

Linezolid

Metronidazole

Phenoxymethylpenicillin

Timethoprim

Tinidazole

A

Metronidazole causes a disulfiram like reaction with alcohol causing flushing, headaches and vomiting amongst other symptoms

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11
Q

Severe optic neuropathy may occur with the use of this antibiotic and as such visual function should be monitored regularly if treatment is required for longer than 28 days.

Aztreonam

Benzylpenicillin sodium

Flucloxacillin

Linezolid

Metronidazole

Phenoxymethylpenicillin

Timethoprim

Tinidazole

A

Linezolid
The CHM advises that patients should be warned to report symptoms of visual impairment due to the risk of severe optic neuropathy.

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12
Q

This antibiotic is cautioned when used by inhalation in those suffering with haemoptysis.

Aztreonam

Benzylpenicillin sodium

Flucloxacillin

Linezolid

Metronidazole

Phenoxymethylpenicillin

Timethoprim

Tinidazole

A

Aztreonam is cautioned for use when used by inhalation in patients suffering with haemopytsis - this is due to risk of further haemorrhage.

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13
Q

Cholestatic jaundice may occur very rarely, up to two months after treatment with this antibiotic has stopped.

Aztreonam

Benzylpenicillin sodium

Flucloxacillin

Linezolid

Metronidazole

Phenoxymethylpenicillin

Tinidazole

A

Cholestatic jaundice and rarely hepatitis may occur very rarely, up to two months after treatment with flucloxacillin has been stopped

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14
Q

A 67-year-old male who has been prescribed topical alprostadil (prostaglandin E1) for erectile dysfunction.

Apply liberally to scalp

Condoms should be used to avoid local reactions and exposure of this agent to women of childbearing age or those who are pregnant

Do not take this medication with any herbal product

If you experience numbness or tingling of your finger or toes, stop your medication immediately and contact your doctor

If you wash your hands with soap within 8 hours of application, they should be treated again with cream

Immediately contact the hospital emergency department if you experience abnormal heart rhythms

Using a nit comb with this is effective

This medication is most effective at night

A

Condoms should be used to avoid local reactions and exposure of this agent to women of childbearing age or those who are pregnant
Prostaglandin E1 and E2 induce labour and are contraindicated in women of childbearing age, pregnant, or those who are breast feeding.

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15
Q

A 17-year-old girl who has been prescribed permethrin for scabies.

Apply liberally to scalp

Condoms should be used to avoid local reactions and exposure of this agent to women of childbearing age or those who are pregnant

Do not take this medication with any herbal product

If you experience numbness or tingling of your finger or toes, stop your medication immediately and contact your doctor

If you wash your hands with soap within 8 hours of application, they should be treated again with cream

Immediately contact the hospital emergency department if you experience abnormal heart rhythms

Using a nit comb with this is effective

This medication is most effective at night

A

If you wash your hands with soap within 8 hours of application, they should be treated again with cream

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16
Q

A patient has been diagnosed with Clostridioides difficile infection that is moderate in severity. A hospital consultant asks which is the most appropriate antibiotic to prescribe.

a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

17
Q

A patient who is HIV positive is deemed to be at risk of opportunistic infections and requires prophylactic treatment for Pneumocystis jirovecii pneumonia. Which antibiotic is most appropriate?
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

Co-trim is the drug of choice in the treatment and prophylaxis of penumocystits

18
Q

You are a ward based clinical pharmacist on a ward round with several junior doctors. It is brought to your attention that a patient has developed osteomyelitis and one of the junior doctors wishes to know which antibiotic is most suitable for this condition.
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

Fusidic acid is indicated for penicillin-resistant staphylococcal infections including osteomyelitis.

19
Q

A doctor calls to query the use of antibiotics in Lyme disease with the intention of prescribing a treatment course for a patient with suspected Lyme disease. The patient is allergic to penicillins, tetracyclines and cephalosporins. Which of the following would you suggest?
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

20
Q

You are giving a training session on the treatment on acne vulgaris to some trainee pharmacists. A trainee asks which oral antibiotics are suitable for use in the treatment of acne vulgaris.
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

21
Q

Whilst running an educational workshop you are asked which antibiotic should have additional monitoring in patients with biliary obstruction.
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

Fusicid acid is cautioned for use in biliary disease or biliary obstruction as elimination may be reduced leading to toxic effects.

22
Q

Which antibiotic requires the use of ‘ideal weight for height’ to help prevent excessive dosage in obese patients?
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

Amikacin use in obese patients requires the use of ‘Ideal weight for height’ to calculate dose. Serum amikacin must be closely monitored also

23
Q

Which antibiotic is a causative factor in dental hypoplasia and as such is contraindicated in children under 12?
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

Deposition of tetracyclines in growing bones and teeth causes staining and occasionally dental hypoplasia and they should NOT be given to children under 12

24
Q

An antibiotic which when given as a multiple daily dose regimen, should have a peak serum concentration NOT exceeding 30 mg/L.
a) Amikacin
b) Azithromycin
c) Ceftazidime
d) Co-trimoxazole
e) Ertapenem
f) Fidaxomicin
g) Fusidic acid
h) Tetracycline

A

When given as a multiple daily dose regimen amikacin ‘peak’ serum concentration should NOT exceed 30 mg/L.

25
You are working as the on-call pharmacist. The on-call doctor calls to inform you that an in-patient has been diagnosed with Pneumocystis jirovecii pneumonia. The doctor is seeking advice regarding which antibiotic to prescribe. What should you recommend? a) Amikacin b) Azithromycin c) Ceftazidime d) Co-trimoxazole e) Ertapenem f) Fidaxomicin g) Fusidic acid h) Tetracycline
Co-trimoxazole is the drug of choice in the treatment and prophylaxis of Pneumocystis jirovecii pneumonia