Salamat D.O.C

Question 1

Cyanide poisoning

Answer 1

Nitrite

Question 2

Nitrite MOA

Answer 2

induces Methemoglobin formation

Question 3

Nitrates in Angina

Answer 3

MOA:
-	Decrease in systemic vascular resistance
-	Vasodilates & Venodilates
S/E: headache
CI: Sildenafyl (Viagra)

Question 4

Malignant Hyperthermia DOC:

Answer 4

Dantrolene

-Succinylcholine

Question 5

Pheochromocytoma

DOC:

Answer 5

• Phenoxybenzamine

- Phentolamine

Question 6

Acute Gouty Arthritis DOC

Answer 6

Colchicine

Question 7

Colchicine MOA

Answer 7

Inhibits Microtubule assembly

Question 8

Chronic Gout DOC

Answer 8

Allopurinol

Question 9

Allopurinol MOA

Answer 9

Inhibit Xanthine oxidase

Question 10

Rheumatoid Arthritis + History of Peptic Ulcer

Answer 10

COX inhibitor

Question 11

If (+) allergy to Penicillin give

Answer 11

Erythromycin

Question 12

If (+) GI upset to Erythromycin

Answer 12

If (+) GI upset to Erythromycin

Question 13

Still with allergy give

Answer 13

Linezolid

Question 14

Choriocarcinoma DOC

Answer 14

Methotrexate

Question 15

Methotrexate MOA

Answer 15

Inhibit Dihydrofolate reductase

Question 16

Breast + Ovarian Ca DOC

Answer 16

Paclitaxel

Question 17

Islet Cell Tumor DOC

Answer 17

Streptozocin

Question 18

AML DOC

Answer 18

Cytarabin

Question 19

Auer Rods

Answer 19

AML

Question 20

Pancreatic Ca & Colon Ca DOC

Answer 20

5 FU

Question 21

5 FU MOA

Answer 21

Inhibit thymidylate synthase

Question 22

Bronchogenic Ca DOC

Answer 22

Cisplastin / Cyclophosphamide + Etoposide
-S/E: Hemorrhagic Ca
oTx: Mesna

Question 23

Cisplatin Side effect

Answer 23

oOtotoxicity

oNephrotoxicity

Question 24

Anti-neoplastic for Brain Tumors

Answer 24

• Nitrosureas

- Lunostin, Corbostyl

Question 25

iron Toxicity

Answer 25

Desferoxamine

Question 26

Hemosiderosis

Answer 26

- > 5 grams Iron/day | - Multiple drug transfusions

Question 27

Organophosphate Poisoning

Answer 27

- Atropine | - Pralidoxine

Question 28

Example of insectisides

Answer 28

Malathione/ Parathione

Question 29

Benzodiazepine Toxicity

Answer 29

Diazepam | DOC:Flumazenil

Question 30

INH Toxicity

Answer 30

- Vit B6 | - Pyridoxine

Question 31

Toxic Metabolite of INH

Answer 31

Acetylhydralazine

Question 32

Warfarin Toxicity

Answer 32

- Vitamin K | - Fresh Frozen Plasma

Question 33

Heparin Toxicity

Answer 33

Protramine Sulfate

Question 34

Opioid / Narcotic Toxicity

Answer 34

- Naloxone | - Ex. Morphine & Codeine

Question 35

- Best cough suppression | - Mu Receptor

Answer 35

Codein

Question 36

Codein Side Effect

Answer 36

Respiratory Arrest

Question 37

Diabetic + Proteinuria

Answer 37

Angotensin Receptor Blocker/ ACE inhibitor

Question 38

Leptospirosis - Tx & Prophylaxis

Answer 38

Doxycycline

Question 39

Weil’s Disease Treatment

Answer 39

Penicillin

Question 40

Syphillis

Answer 40

Penicillin

Question 41

Bronchodilator to reduce uterine contractions in premature labor

Answer 41

Ritodrine

Question 42

Pre-op drug to control thyrotoxicosis

Answer 42

Propranolol

Question 43

Pre-op Bowel Prep antibiotic

Answer 43

Methylmycine/ Neomycine

Question 44

Decrease vascularity of thyroid gland pre-op

Answer 44

Lugol’s Solution

Question 45

Pheochromocytoma Pre-op

Answer 45

Phenoxybenzamine

Question 46

Induction anesthesia to decrease oral secretion

Answer 46

Atropine

Question 47

Most Cardiotoxic anesthesia

Answer 47

Bupivacaine

Question 48

Notorious to cause hepatitis

Answer 48

Halothane

Question 49

Laughing gas

Answer 49

Nitrous Oxide

Question 50

Diffuse Anoxia

Answer 50

Nitrous Oxide

Question 51

Status epilepticus

Answer 51

- Barbiturates | - CI with phorphyria

Question 52

Causes dissociative Anesthetic

Answer 52

Ketamine

Question 53

Can penetrate Burn Eschar

Answer 53

Mefenide Acetate

Question 54

Drug for Asthma with Narrow Therapeutic Index

Answer 54

Aminophylline

Question 55

Synchonism

Answer 55

Quinine / Quinidine

Question 56

Anti-malarial drug for Relapse

Answer 56

Primaquine

Question 57

CYP 2 C9 Complex 1/ Electron Transport Chain

Answer 57

Phenobarbital

Question 58

Blocks Complex 1

Answer 58

Rotinone

Question 59

Blocks Complex 4

Answer 59

Cyanide & Carbon Monoxide

Question 60

Oligomycin

Answer 60

- ATP Synthase - Fo fraction - Complex 5

Question 61

Blocks Complex 3

Answer 61

Blocks Complex 3

Question 62

- Inhibit RENAL DIHYDROPEPTIDASE INHIBITOR - Prevents degradation of IMIPANEM - Imipanem + Cilastatin

Answer 62

Cilastin

Question 63

Carbidopa + Levodopa

Answer 63

-Carbidopa prevents the peripheral carboxylation of LEVODOPA (does not reach the brain)

Question 64

What is the DOC for Chronic Gout

Answer 64

-Allopurinol | o Inhibits xanthine oxidase

Question 65

Orlistat

Answer 65

- Lipase inhibitor | - Causes flatulence & Steatorrhea