Salivary Gland Disorders Flashcards
(31 cards)
List the 8 non-neoplastic disorders of salivary gland origin.
- Mucocele/Ranula
- Sialothiasis
- Acute/chronic sialadenitis
- Sialadenosis
- Xerostomia
- Benign lymphoepithelial lesion (BLEL)
- Sjögren syndrome
- Necrotizing sialometaplasia
What causes a mucocele?
Rupture of salivary gland duct -> spillage of mucin
In what age group and at what location are mucoceles the most common?
Children/young adults; lower lip
What is a distinctive clinical feature of a mucocele?
Translucent to bluish hue
A __________ is a type of mucocele seen on the floor of the mouth, and arises from the sublingual gland.
Ranula
T/F: All mucoceles are treated with marsupialization.
False
Just Ranulas - making incision into the lesion and suturing the edges
Which gland is most often affected with sialolithiasis?
Submandibular gland (80%)
What is a lithotripsy?
A way to retrieve some sialolithiasis in major glands
What is acute/chronic sialadenitis?
Inflammation of salivary gland
What common microorganisms cause sialadenitis?
Bacteria - staph
Viral - mumps
Which glands are most often associated with sialadenitis?
Acute - parotid (pus coming from duct)
Chronic - submandibular
What allows you to differentiate between sialadenitis and a sialolith?
Radiograph
T/F: Sialadenosis is due to an infection.
False
Associated with underlying condition - diabetes, malnutrition, alcoholism, bulimia
What conditions does xerostomia predispose a patient to?
- Mucosal injury due to lack of lubrication
- Candidiasis
- Increased cervical caries
T/F: A patient on several different drugs is at more risk for xerostomia.
True
Esp. Antihistamines, antidepressants, sedatives, antihypertensives
T/F: Frothy saliva is a sign of xerostomia.
True
Which lesion can be characterized by “blossoms on a tree” look in a radiograph?
BLEL
In which disorder do you see remnants of ductal epithelium in the form of epimyoepithelial islands?
BLEL
T/F: Sjögren syndrome is sometimes thought of as a continuation of BLEL.
True
What is the difference between primary and secondary Sjögren syndrome?
Primary (sicca) - xerostomia and keratoconjunctivitis
Secondary - sicca plus another autoimmune disease
T/F: Sjögren syndrome has a male predilection.
False
More common in females
T/F: Serology is a specific test for Sjögren syndrome.
False
Is often used as diagnostic tool but is non-specific
Which antibodies can help diagnose Sjögren syndrome?
Elevated IgG, rheumatoid factor, anti-nuclear autoantibodies, anti-SS-A, anti-SS-B
What histopathogical features can be used to diagnose Sjögren syndrome?
Labial salivary gland biopsy
Looking for aggregates of >50 lymphocytes and plasma cells in a gland
