Salivary Gland Pathology - SY

Question 1

What fluid makes up the parotid gland?

Answer 1

100% serous

Question 2

What fluid makes up the submandibular gland?

Answer 2

Mostly serous, some mucous

Question 3

What fluid makes up the sublingual gland?

Answer 3

Mostly mucous, some serous

Question 4

What is a mucocele caused by?

Answer 4

Break in ductal system due to trauma

Question 5

What is present with mucin + granulation tissue?

Answer 5

Mucocele

Question 6

What is this?

Answer 6

Mucocele

Question 7

What is an example of a special type of mucocele?

Answer 7

Ranula

Question 8

Where are ranulas found?

Answer 8

ONLY on sublingual gland (under tongue)

Question 9

What is a sialolith?

Answer 9

Saliva gets calcified, turns into stone and blocks mucous from exiting duct

Question 10

Where are sialoliths located?

Answer 10

Whartons duct (connects submandibular with sublingual gland)

Question 11

What can pus coming out of an area indicate?

Answer 11

Somewhere nearby is a salivary stone

Question 12

How can you see a sialolith?

Answer 12

Occlusal radiograph

Question 13

What is the dx if pt comes in and says
“oh nooo a part of my mouth plopped out?”

Answer 13

Necrotizing sialometaplasia

Question 14

What is necrotizing sialometaplasia characterized as?

Answer 14

Area of ulceration

Question 15

What are symptoms of Sjogren’s?

Answer 15

Autoimmune
Dry mouth, dry eyes
Bilateral enlargement of parotid gland

Question 16

How do you diagnose sjogrens?

Answer 16

Lower lip biopsy, should have lymphoid clusters
Certain amount of clusters = sjogrens

Question 17

What is the most common benign salivary gland tumor?

Answer 17

Pleomorphic adenoma

Question 18

Where are monomorphic adenomas found?

Answer 18

Upper lip

Question 19

What gland is involved with papillary cystadenoma lymphomatosum?

Answer 19

Parotid gland (95%)

Question 20

What are characteristics of Papillary cystadenoma lymphomatosum?

Answer 20

Parotid
Bilateral
Middle aged MALES
Smoking

Question 21

What is the second most common benign salivary gland neoplasm?

Answer 21

Papillary cystadenoma lymphomatosum

Question 22

What is oncocytoma?

Answer 22

Rare neoplasm

Question 23

What is this?

Answer 23

Monomorphic adenoma
because on upper lip

Question 24

What is the most common MALIGNANT salivary gland neoplasm?

Answer 24

Mucoepidermoid carcinoma

Question 25

What is typically mistaken for a mucocele?

Answer 25

Mucoepidermoid carcinoma

Question 26

DDx

Answer 26

Mucocele or mucoepidermoid carcinoma

Question 27

What is the best hystologically recognized salivary gland tumor?

Answer 27

Adenoid cystic carcinoma

Question 28

What typically histologically presents as swiss cheese?

Answer 28

Adenoid cystic carcinoma

Question 29

What is a common MALIGNANT MINOR salivary gland neoplasm?

Answer 29

Polymorphous low-grade adenocarcinoma (PLGA) - not on parotid, sublingual, or submand gland

Question 30

What neoplasm favors the palate?

Answer 30

PLGA - cause its a malignant MINOR neoplasm and lots of minor glands on palate

Question 31

What is this?

Answer 31

PLGA

Question 32

What neoplasm histologically appears with indian filing?

Answer 32

PLGA

Question 33

Where is acinic cell carcinoma typically found?

Answer 33

Parotid gland (not exclusively)

Question 34

What speed does acinic cell carcinoma grow?

Answer 34

Slow growing

Question 35

What does acinic cell carcinoma histologically present as?

Answer 35

Serous acinar cells (looks like parotid gland)

Question 36

What is this?

Answer 36

Acinic cell carcinoma

Question 37

What is long standing pleomorphic adenoma if not treated?

Answer 37

A malignant transformation of pleomorphic adenoma -> benign mixed tumor (carcinoma ex-pleomorphic adenoma)

Question 38

What are characteristics of carcinoma ex-pleomorphic adenoma?

Answer 38

Rapid growth Older adults Pain and ulceration Histologically - benign mixed tumor

Question 39

What are the benign salivary gland neoplasms? List them

Answer 39

1. Pleomorphic adenoma 2. Monomorphic adenoma 3. Papillary Cystadenoma Lymphomatosum (Wharthin's tumor) 4. Oncocytoma

Question 40

What are the malignant salivary gland neoplasms? List them

Answer 40

1. Mucoepidermoid carcinoma 2. Adenoid cystic carcinoma 3. Polymorphous low-grade adenocarcinoma (PLGA) 4. Acinic cell carcinoma 5. Carcinoma ex- pleomorphic adenoma 6. Adenocarcinoma NOS

Question 41

What pathology is painless and slow growing?

Answer 41

Benign mixed tumor (plemorphic adenoma)