Salmonella Flashcards
Morphology Salmonella
gram -
motile H antigen
non-spore forming
Cultivation Salmonella
facultative anaerobics
4-5mm round, smooth, convex, shiny colonies
Biochemical activity Salmonella
lactose -
H2S producer
gas producer( except S. Typhi)
Salmonella-enteritis: how do you get infected? And what’s the latency?
Chicken/duck/eggs/pork meat
takes 1-2 days
Symptoms of Salm-Enteritis
Nausea Vomiting Dizziness Headache Sore muscles Stomach cramps Thin,watery, bloody mucous diarrhoae
Therapy Salm-Enteritis
not too bad: fluid replacement.
Fever+ infections= Fluoroquinolones
(ampicillin, cephalosporins)
Pathogenesis Salm-Typhi
Latency time
first 2 weeks are symptom less.
Invastion thourgh Peyer’s patches (GALL BLADDER) M cells. -> infection macrophages -> primary bacteriaemia -> secondary bacteriaemia
Symptoms of Salm-Typhi
Fever bradycardia hepatosplenomegaly altered consciousness rose patches on stomach/ chest!! leukopenia, eosinophilla constipation (sketchy) osteomyolitis sickle cell ( sketchy)
Diagnosis Salm-Typhi
blood
bone marrow biopsy
stool
urine
Serological method Salm-Typhi
Gruber-Widal tube agglutination (O-H antigens)
Theraphy Salm-Typhi
Ciprofloxacin
cephalosporin
Prevention Salm-Typhi
Vaccination Typhim
