SAM II Exam I Material - Gastrointestinal Flashcards
(124 cards)
This is a specific antidote used in Tylenol toxicity

N-acetyl cysteine
N-acetyl cysteine treats acetaminophen (Tylenol) poisoning by binding the poisonous forms of acetaminophen that are formed in the liver
Considering the risks and diagnostic value of each biopsy technique, which biopsy method is the best option for dogs with non-infiltrative/neoplastic liver disease?
- FNA
- Menghini tru-cut
- Laparotomy/laparoscopy
Laparotomy/laparoscopy
T/F: If you note microcytic, hypochromic anemia in a yorkshire terrier, this can be an indicator of poor iron metabolism associated with portosystemic shunts
True
What is the drug of choice for treatment of histiocytic ulcerative colitis?
enrofloxacin
Since histiocytic ulcerative colitis is a bacterial infection, it is antibiotic responsive. Enrofloxacin is typically effective. It is critical to treat for at least 8 weeks (even if the patient feels normal by week 2). Stopping antibiotics before 8 weeks has been associated with recurrence of infection and resistance to enrofloxacin.
Lady, a 6-year-old Labrador has been under your care for CH for 2 months. Today she presents like this. What do you recommend as the first line of treatment?
- Drain all the fluid by abdominocentesis
- Spironolactone at 2 mg/kg/day
- Furosemide at 2 mg/kg/day
- Colloid like hetastarch

Spironolactone at 2 mg/kg/day
T/F: ALT and AST are very liver-specific
False
- ALT is very liver specific*
- AST is also from skeletal muscle and cardiac muscle*
T/F: Both cats and dogs with acute pancreatitis will regularly demonstrate abdominal pain

False

T/F: The current combination of tests with the best test accuracy for the diagnosis of acute pancreatitis is cPL and abdominal ultrasound
True

What is the specific treatment for aflatoxicosis?
Plasma & Vitamin K
T/F: Xylitol toxicosis is associated with hyperglycemia
False
Xylitol stimulates insulin release and results in hypoglycemia
What is the role of H2 blockers and proton pump inhibitors in the medical treatment of esophagitis?
neutralize acid secretion
T/F: Concurrent IBD, cholangiohepatitis and pancreatitis are common in cats
True
These concurrent diseases are referred to collectively as triaditis

What liver disease is associated with the highest mortality rate in cats?
hepatic lipidosis
Lipid accumulation in hepatocytes eventually results in loss of hepatic function.
- Increased triglyceride deposition associated with starvation due to mobilization of fatty acids from lipid stores
- Insufficient insulin – fat stores used for energy
Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:
weight loss and protein loss
small bowel (often in chronic)
What is the mechanism of action of lactulose in resolving hepatic encephalopathy?
- Laxative
- Purgative
- Resolves dysbiosis
- Ion trapping
- Resolves alkalosis
Ion trapping
lactulose acidifies the GIT and traps ammonia; decreases absorption of harmful substances by increasing GIT transit

Current evidence based medicine supports the diagnosis of specific therapy for acute pancreatitis. Which therapy in dogs is not specifically indicated?
- Crystalloid resuscitation
- Fentanyl CRI
- Broad spectrum antibiotics
- Maropitant, NK1 receptor antagonist
Broad-spectrum antibiotics
Which of these is/are classic feature(s) of small bowel enteritis in contrast to large bowel enteritis?
- mucous
- tenesmus
- dyschezia
- hematochezia
- low volume
- hypocobalaminemia
hypocobalaminemia
hypocobalaminemia is more characteristic for small intestinal enteritis
T/F: Both cats and dogs will have obvious ultrasonography changes in acute pancreatitis in >70% of cases

False
Cats are more prone to chronic pancreatitis than acute pancreatitis and it’s difficult to diagnose chronic pancreatitis on ultrasound

T/F: Steroids are indicated for treatment of hepatic lipidosis in cats

False!
T/F: Both cats and dogs will frequently have cholangitis and enteritis accompanying pancreatitis

False

T/F: When using maropitant as an anti-emetic in acute liver disease, it is standard to decrease the recommended dose by ~25%
True
Maropitant is metabolized in the liver, so we generally decrease the dose by ~25% in our acute liver disease patients
Which of these is not a good treatment for IBD in these cats?
- Budesonide
- Prednisolone
- Metronidazole
- Chlorambucil
- Azathioprine

Azathioprine
The most common form of pancreatitis in cats is:

chronic pancreatitis
When submitting a liver biopsy, what special stain would you request if you want to confirm cirrhosis and fibrosis?
Masson’s trichome





















