Samplex 2014 A Flashcards Preview

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Flashcards in Samplex 2014 A Deck (64)
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1

A 54 year old asymptomatic female consulted because of left breast mass. P.E. revealed a 5x3 cm firm, movable non-tender mass with irregular borders and overlying peau d'orange skin. Nonpalpable axillary nor supraclavicular lymph node. Core needle biopsy revealed invasive ductal carcinoma. The most likely clinical stage is:

A. Stage III
B. Stage III A
C. Stage III B
D. Stage IV

C

2

The least invasive biopsy technique to determine stromal invasion from ductal breast cancer is:

A. Fine needle aspiration biopsy
B. Core needle biopsy
C. Excision biopsy
D. Incision biopsy

B

3

The surgical technique for primary operable breast cancer that involves total mastectomy with axillary dissection is:

A. Lumpectomy plus radiotherapy
B. Breast conservation surgery
C. Modified radical mastectomy
D. Subcutaneous mastectomy

C

4

A 40 y.o. asymptomatic female consulted because of a 6x5 cm hard fixed and ulcerated mass with multiple satellite skin nodules. No axillary lymph node was palpated. FNAB revealed ductal carcinoma. The primary treatment based on her clinical stage is:

A. Surgery
B. Palliative radiotherapy
C. Palliative hormonal therapy
D. Neoadjuvant chemotherapy

D

5

A mutation in this gene that congers an 80% lifetime risk in the development of breast cancer is:

A. Chromosome 10
B. Chromosome 14
C. Chromosome 17
D. Chromosome 20

C

6

A surgical procedure for primary operable breast cancer with superior cosmetic outcome and comparable survival rate to modified radical mastectomy is:

A. Lumpectomy plus radiotherapy
B. Breast conservation surgery
C. Lumpectomy only
D. Axillary dissection only

B

7

The therapeutic strategy to destroy any distant occult micrometastasis after curative modified radical mastectomy for localized ER/PR negative breast cancer is best achieved by:

A. Adjuvant chemotherapy
B. Adjuvant radiotherapy
C. Neoadjuvant chemotherapy
D. Induction radiotherapy

B

8

A 28 y.o. female with a 2x2 cm hard movable left upper outer breast mass. No axillary node palpated but with associated persistent mild to moderate headache and dizziness. FNAB revealed ductal cancer. The next best step in the management will be:

A. Chest x-ray
B. CT scan of the head
C. Mammography
D. Liver ultrasound

B

9

The pathologic basis in the diagnosis of peau d'orange skin is:

A. Dermal neovascularization
B. Proliferation of inflammatory cells
C. Tumor blockage of dermal lymphatics
D. Invasion of Cooper's ligament

C

10

Among the different histopathologic type of breast cancer, which one is the most common?

A. Invasive ductal cancer
B. Medullary cancer
C. Mucinous cancer
D. Tubular cancer

A

11

A 40 yo female with no palpable breast mass was found to have suspicious microcalcification on screening mammography. Needle localization biopsy revealed ductal carcinoma in situ. Her clinical stage will be:

A. 0
B. I
C. IIA
D. IIB

A

12

Another local regional intervention for advanced breast cancer other than surgery:

A. Chemotherapy
B. Radiotherapy
C. HRT
D. electrocautery

B

13

A 30 y.o. male presented with a solid nontender testicular mass. Biopsy of this mass would probably most reveal:

A. Leydig cell tumor
B. Embryonal cell carcinoma
C. Seminoma
D. Teratoma

C

14

A patient who underwent radical orchiectomy for a testicular malignancy showed increased LDH levels on follow up. To diagnose lymphatic recurrence and spread of the tumor, you must do:

A. inguinal lymph node biopsy
B. chest CT scan
C. abdominal CT scan
D. supraclavicular node aspiration biopsy

C

15

The following combination of events lead to prostatic enlargement

A. Increase in DHT levels and transfroming growth factor
B. Decline in the epidermal growth factor and transforming growth factor
C. Agein and a decline in the testosterone levels
D. Inrease in the epidermal growth factor and DHT levels

D

16

What is the most important diagnostic test for prostatic enlargement?

A. Prostate specific antigen (PSA)
B. Digital Rectal Exam (DRE)
C. KUB Xray
D. Ultrasound

B

17

Alpha adrenergic receptors are used for LUTS because of this mechanism:

A. prevents conversion of testosterone to DHT
B. stimulate smooth muscle contraction
C. stimulate apoptosis
D. increased vasodilation

B

18

The most common pathophysiology of orchitis is:

A. Local spread of perianal microflora
B. Contiguous spread from urethritis
C. Hematogenous spread from the urinary tract
D. Lymphatic spread from inguinoscrotal infections

B

19

An exophytic enlarging growth at the area of the penile glans would present on histopathology as:

A. Pseudoepitheliomatous hyperkeratosis
B. Balanitil xerotica obliterans
C. Squamous cell carcinoma
D. Leukoplakia

C

20

Prostate cancer commonly arises in which zone of the prostate?

A. Peripheral
B. Periurethral
C. Transitional
D. Central

A

21

A 67 y.o. male presenting with LUTS and DRE findings of enlarged, nodular prostate must be screened for:

A. benign prostatic hyperplasia
B. prostatic calcification
C. prostatic ca
D. tuberculous prostatitis

C

22

A 6 y.o. boy underwent radical orchiectomy. His biopsy result will most probably be:

A. immature teratoma
B. embryonal cell ca
C. seminoma
D. yolk sac tumor

D

23

Which of the following is a characteristic of priapism?

A. it occurs during sexual stimulation
B. it resolves during ejaculation
C. both the glans and the shaft are rigid on palpation
D. the penis is often painful and tender

D

24

A patient has true premature ejaculation if he reaches orgasm and ejaculates

A. within 10 minutes
B. prior to insertion of the penis into the vagina
C. earlier than his partner
D. in the absence of sexual stimulation

B

25

The primary hormone responsible for male sexual behavior is:

A. estrogen
B. progesterone
C. testosterone
D. prolactin

C

26

Hyperthyroidism can cause erectile dysfunction because of:

A. increased prolactin level
B. decreased estrogen level
C. increased estrogen level
D. impaired penile perfusion

C

27

Which of the following statement is true regarding erectile dysfunction?

A. psychogenic ED is the most common cause of ED
B. there is a higher risk of ED in men with CVD, hypertension and diabetes
C. less than 50% of patients have organic cause for their ED
D. it is normal in the elderly and doesn’t warrant treatment

B

28

Which of the following occurs with Sildenafil intake?

A. cavernous muscle constriction
B. PDE-5 stimulation
C. increase cGMP
D. penile detumescence

C

29

Which of the following demonstrates a possible organic cause of erectile dysfunction?

A. px A has good erections during masturbation but poor erections during sexual intercourse with a partner
B. px B claims to have good erections with certain partners but not with all of his partners
C. px C complains of gradual loss of erection in span of 1 yr
D. px D has difficulty achieving good erections after a long day’s work at the office

C

30

Priapism is a prolonged erection that persist for

A. greater than 1 hour
B. greater than 2 hours
C. greater than 3 hours
D. greater than 4 hours

D