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[OS 215] OB-GYN Patho E2 > Samplex 2017 > Flashcards

Samplex 2017 Flashcards

1
Q

True of phimosis:
a. The prepuceal orifice is dilated
b. May be due to anomalous development.
C. Infections have no role in Its development
d. Will not cause scarring

A

B

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2
Q

Non¬specific inflammation of the glans and prepuce is due to which organism?

a. Candida albicans
b. Syphilis
c. Granuloma inguinale
d. Herpes

A

A

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3
Q

Poor hygiene is a common cause of

a. Phimosis
b. Specific inflammations
C. Hypospadias
d. Epispadias

A

A

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4
Q

Condyloma acuminaturn will histologically present with

a. Absence of epithelial maturation
b. Thinned out epithelial layer
c. Raisinoid appearance of squamous cells
d. Flattened basal membrane

A

C

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5
Q

This organism is the most common cause of penile carcinoma in situ

a. HPV 6
b. HPV 11
c. HPV 16
d. All of the above

A

C

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6
Q

Most important histologic features of penile carcinoma in¬ situ:

a. Full thickness dysplasia
b. Mitotically active epithelial cells
c. Basement membrane is intact
d. Well¬ differentiated

A

C

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7
Q

True of verrucous carcinoma of the penis

a. Cells may look bland¬-looking
b. Doesn’t metastasize
c. Tumor is unusually large and focal
d. All of the above

A

D

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8
Q

Cryptorchidism is most commonly associated with

a. Trisomy 13
B. Klinefelter syndrome
C. Increased testosterone levels
d. Idiopathic causes

A

A

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9
Q

Histological features of cryptorchidism

a. Leydig cell prominence
b. No maturation of germ cells
C. Fibrous hyalinization of stroma
d. All of the above

A

A

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10
Q

Testicular inflammations usually arise from

a. Infections from the urinary bladder
b. infections from the lymphatic channels
C. Infections from the epididymis
d. all of the above

A

D

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11
Q

Which of the following is a complication of testicular inflammation?

a. sterility
b. necrosis
c. abcess formation
d. edema and congestion

A

A

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12
Q

True of testicular torsion

a. gradually intensifying pain
b. bell¬clapper abnormality is the most common cause among all ages
c. hemorrhagic infarction can ensue if left untreated
d. caused by twisting of the epididymis

A

C

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13
Q

Most common testicular tumor

a. sex cord stromal tumors
b. germ cell tumors
c. carcinomas
d. all of the above

A

B

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14
Q

True of testicular dysgenesis syndrome

a. spectrum includes hypospadia formation and cryptorchidism
b. is not a risk factor in the development of germ cell tumors
c. sperm quality is spared
d. its development is related to intrauterine exposure to androgens

A

A

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15
Q

Clinical features of germ cell tumors

a. lymphatic spread is most commonly seen in non-seminomatous germ cell tumors
b. metastasis starts in the para¬aortic nodes
c. testicular enlargement is accompanied by pain
d. seminomas usually metastasize earlier than non-seminomatous germ cell tumors

A

B

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16
Q

Primordial germ cells are the origins of which tumor?

a. embryonal carcinoma
b. yolk sac tumor
c. seminoma
d. all of the above

A

D

17
Q

Histologic feature(s) of seminomas:

a. tumor cells are divided by hyaline bands
b. infiltrates are usually polymorphonuclear cells
c. absence of hemorrhage and necrosis
d. absence of giant cells and syntiotrophoblasts

A

C

18
Q

Spermatocytic seminoma is histologically different from seminoma due to the following feature(s):

a. absence of extra¬testicular sites of origin
b. is not seen as a component of germ cell tumors
c. is associated with intratubular germ cell neoplasia
d. all of the above

A

D

19
Q

Histologic feature of embryonal carcinoma

a. absence of hemorrhage and necrosis
b. tumor cells may show areas of alveolar differentiation
c. giant cells are absent
d. mitosis is rare

A

B

20
Q

Schiller ¬Duval Bodies have this characteristic appearance:

A. Glomeruloid
B. Hypernephroid
C. Rosette¬shaped
D. Reticular

A

A

21
Q

Feature(s) of choriocarcinoma

a. primary tumor is usually small and hemorrhagic
b. metastatic tumors usually with preserved neoplastic syncytiotrophoblasts and
cytotrophoblasts
c. notoriously aggressive and widely metastasizing
d. all of the above

A

NA

22
Q

Feature(s) of teratoma:

a. most teratoma variants are mature
b. teratomas mixed with other germ cell components are usually seen in children
c. sarcoma is the most common malignant transformation seen in teratomas
d. all of the above

A

A

23
Q

Which of the following is the most common germ cell among children?

a. mature cystic teratoma
b. yolk sac tumor
c. seminoma
d. embryonal carcinoma

A

B

24
Q

Most common testicular germ cell tumor in adults

a. seminoma
b. choriocarcinoma
c. mixed germ cell tumor
d. yolk sac tumor

A

A

25
Q

p63 Immunohistochemical stain will stain the

a. fibroblasts
b. luminal cells
c. myoepithelial cells
d. the blood vessels

A

C

26
Q

Which of the following is a fibroepithelial lesion?

a. ductal carcinoma in situ cribiform type
b. ductal carcinoma in situ micropapillary type
c. fibroadenoma
d. invasive lobular carcinoma

A

C

27
Q

Which of the following breast lesions is malignant and invasive?

a. ductal carcinoma in situ cribiform type
b. ductal carcinoma in situ micropapillary type
c. fibroadenoma
d. invasive lobular carcinoma

A

D

28
Q

Which of the following lesions is benign

a. ductal carcinoma in situ cribiform type
b. ductal carcinoma in situ micropapillary type
c. fibroadenoma
d. invasive lobular carcinoma

A

C

29
Q

Which of the following lesions is intraductal with cookie cutter spaces?

a. ductal carcinoma in situ cribiform type
b. ductal carcinoma in situ micropapillary type
c. fibroadenoma
d. invasive lobular carcinoma

A

A

30
Q

Which of the following lesions is negative for e¬ cadherin?

a. ductal carcinoma in situ cribiform type
b. ductal carcinoma in situ micropapillary type
c. fibroadenoma
d. invasive lobular carcinoma

A

D

31
Q

Aling Maria is a 65 year old woman who presented with a mass on her right breast. She consulted a doctor, and a needle with syringe was inserted into her breast, and the pathologist was able to draw some cells from which a smear was made on a slide. Subsequent tissue biopsy and eventual modified radical mastectomy was performed.

The first diagnostic procedure performed on Aling Maria was:

a. core needle biopsy
b. frozen section biopsy
c. local wide excision biopsy
d. fine needle aspiration biopsy

A

D

32
Q

Aling Maria is a 65 year old woman who presented with a mass on her right breast. She consulted a doctor, and a needle with syringe was inserted into her breast, and the pathologist was able to draw some cells from which a smear was made on a slide. Subsequent tissue biopsy and eventual modified radical mastectomy was performed.

A Nottingham score of II was rendered on the breast lesion of Aling Maria. Which of the following features is not included in the Nottingham scoring system?

a. nuclear grade
b. necrosis
c. mitosis
d. architecture or tubule formations

A

B

33
Q

Aling Maria is a 65 year old woman who presented with a mass on her right breast. She consulted a doctor, and a needle with syringe was inserted into her breast, and the pathologist was able to draw some cells from which a smear was made on a slide. Subsequent tissue biopsy and eventual modified radical mastectomy was performed.

Aling Maria was given Tamoxifen for the breast lesion. The breast lesions is most likely to be:

A. Luminal A
B. Her2/neu positive
C. Triple negative
D. BRCA 1 positive

A

A

34
Q

Aling Maria is a 65 year old woman who presented with a mass on her right breast. She consulted a doctor, and a needle with syringe was inserted into her breast, and the pathologist was able to draw some cells from which a smear was made on a slide. Subsequent tissue biopsy and eventual modified radical mastectomy was performed.

Which of the following choices is the most important prognostic indicator of Aling Maria’s breast lesion?

a. bone metastases
b aneuploidy
c. metastases to lymph nodes
d. hormone receptor assays

A

A

35
Q

Sixty year old Ms Agnes was found to have breast carcinoma which on physical exam and ancillary exams was found to be bilateral and multicentric and with metastatic foci to the ovaries and uterus. Her breast carcinoma follows the characteristics seen in:

a. medullary carcinoma
b. inflammatory carcinoma
c. invasive lobular carcinoma
d. Metaplastic carcinoma

A

C

36
Q

The following are histologic features of medullary carcinoma except for :

a. Well differentiated tubular structures devoid of myoepithelial cells.
b. Solid syncytium like sheets of tumor cells
c. lymphoplasmacytic infiltrates surrounding the tumor cells
d. Pushing (non¬infiltrative ) borders

A

A

37
Q

The immunohistochemical profile of medullary breast carcinoma is likely to be:

a. Negative for ER, PR and HER2 neu receptors
b. Positive for ER and PR but negative for HER2 neu receptors
c. Positive Only for HER2 neu receptors
d. Positive for ER. PR and HER2 neu receptors

A

A

38
Q

The following are histologic features of tubular carcinoma

a Well differentiated tubular structures devoid of myoepithelial cells

b. solid syncytium-¬like sheets of tumor cells
c. lymphoplasmacytic infiltrates surrounding the tumor cells
d. pushing (non infiltrative) borders

A

A

39
Q

Immunohistochemical profile of tubular breast carcinoma is likely to be

a. Negative for ER, PR and HER2 neu receptors
b. Positive for ER and PR but negative for HER2 neu receptors
c. Positive Only for HER2 neu receptors
d. Positive for ER. PR and HER2 neu receptors

A

B

[OS 215] OB-GYN Patho E2 (2 decks)

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