SAS #6 General Drug Class Recommendations

Question 1

ACE inhibitors

Answer 1

Take captopril and moexipril 1 hr before or 2 hrs after meals; food may decrease absorption. Avoid high-potassium foods as ACE inhibitors increase potassium.

Question 2

Analgesic/Antipyretic

Answer 2

Take on an empty stomach as food may slow down absorption.

Question 3

Antacids

Answer 3

take 1hr after or between meals. Avoid dairy foods as the protein in them may increase stomach acid.

Question 4

Anti-anxiety

Answer 4

Caffeine may cause excitability, nervousness, and hyperactivity lessening the anti-anxiety drug effects.

Question 5

Antibiotics

Answer 5

Penicillin generally should be taken on an empty stomach; may take with food if GI upset occurs. Do not mix up with acidic foods: coffee, citrus fruits, and tomatoes; the acid interferes with absorption of penicillin, ampicillin, erythromycin, and cloxacillin.

Question 6

Anticoagulant

Answer 6

High vitamin K produces bloodclotting substance which may reduce drug effectiveness. Vitamin E >400 IU may prolong clotting time and increase bleeding risks.

Question 7

Antidepressants

Answer 7

May be taken with or without food.

Question 8

Antifungal

Answer 8

Avoid taking with dairy products; avoid alcohol.

Question 9

Antihistamines

Answer 9

Take on an empty stomach to increase effectiveness

Question 10

Bronchodilators

Answer 10

With theophylline: high-fat meals increase bioavailability while high carbonate may decrease it. Food increases absorption of Theo-24 and Uniphyl which may cause increased N&V, headache, and irritability.