SaSx FINAL - old material Flashcards
(175 cards)
4 classifications of operative wounds
Clean - created in Sx, no infection
Clean-contaminated - Sx created but hollow viscus or organ w/ bacteria open, no contents spilled, minor break in technique
Contaminated - Sx but gross spillage in hollow viscus organ, minor break in technique
Dirty - implies infection
Risk of infection ______ every hour
doubles
MC source of surgical wound infection
patients endogenous flora, skin and GIT
Prophylactic antibiotic for wound contamination
Cefazolin IV, 30-60 min prior to incision, q90-120 mins intraop
Therapeutic antibiotics for wound contamination
continue 2-3d after resolution of infection
4 stages of wound healing
- Inflammation
- Debridement
- Repair
- Maturation
Inflammatory phase of wound healing
0-5 days
initiated by tissue damage, hemorrhage = 1st response to injury
vasoconstriction - fibrin clot - vasodilation + inc vascular permeability - leukocyte response (macrophages), platelets
WBC leaking from vessels into wound initiates debridement phase
Debridement phase of wound healing
2-5 days
neutrophils and monocytes initiate debridement phase
monocytes = primary cells for wound healing
macrophages - secrete collagenases to remove necrotic tissue, secrete chemotactic + growth factors, recruit mesenchymal cells
Repair phase of wound healing
3-5 days to 2-4 weeks
macrophages stimulate fibroblast and DNA proliferation
acidic + oxygen rich environment
Granulation tissue - barrier to infection, source of special fibroblasts, surface for epithelial migration
Epithelialization + wound contraction
Maturation/Remodelling phase of wound healing
strength of wound optimized d/t changes in the scar, collagen I increases, III decreases
most rapid gain in strength 7-14d post injury
Golden period of wounds
within 6 hours - insufficient microbial replication to cause infection, can usually manage with primary closure
T/F: alcohol is ideal to flush open wounds
false, damages open tissue, never use
Preferred lavage
sterile isotonic saline or LRS
7-8psi (1L saline bag w/ pressure cuff at 300mmHg)
Number one choice for empirical antimicrobial selection to treat a contaminated wound
Clavulanic acid - potentiated amoxicillin (clavamox)
2 antibiotics that you should take a culture before using
fluoroquinolone and aminoglycosides
Compare TAB to silver sulfadiazine
TAB (Triple Antibiotic Ointment)
broad spectrum, prevention, not effective vs Pseudomonas
can retard wound contraction
Silver Sulfadiazine
DOC for wounds, can tx most gram + and - including Pseudomonas
combine w/ aloe vera to reverse wound retardant effects
Layered vs En Bloc debridement
Layered - MC, excise contaminated SQ (careful in cats can delay wound healing), remove isthmus connections, excise in layers
En Bloc - entire wound excised then closed primarily
Debridement mechanism that is highly selective for devitalized tissue only: A) Layered B) En Bloc C) Autolytic D) Biosurgical
C) autolytic
A dog comes in with an infected wound. The owner said they tried to bandage it but it started smelling like tortillas so they came to the vet. You pull off the bandage and notice blue green pigment on the bandage. What is at the top of your differential list?
Pseudomonas. TAB wont work, will need silver sulfadiazine.
Penrose Drain
passive
fluid travels along drain not inside, don’t fenestrate, MC drain in vet med
remove 5-7d later or risk ascending infection.
daily bandage changes, don’t rely on owner
warm compress to promote drainage, not cold compression
don’t do double exit passive drain
make sure adequately clipped + prepped
Jackson Pratt drain
active
fluid travels inside fenestrated tubing, exits dorsal to wound
strict aseptic technique for placement
aggressive en bloc debridement before closure
remove when fluid: 5ml/kg/d or 0.2ml/kg/h
Modified butterfly catheter
small animals or wounds in challenging areas
Most common used bandage in vet med A) adherent B) non-adherent C) Occlusive D) Semi-occlusive
D - semi-occlusive, allows air to penetrate + exudate to escape from wound surface
Can you use a wet to dry bandage on granulation tissue?
No! Will disrupt healing tissue when removed