Schizophrenia

Question 1

schizophrenia spectrum

Answer 1

a group of psychotic disorderes by severe disturbances of thought and associative looseness, impaired reality testing and limited socialization

Question 2

psychosis

Answer 2

total inability to recognize ability reality, not a diagnosis by a symptom

Question 3

schizophreniform

Answer 3

duration of symptoms is < 6 months

Question 4

schizoaffective

Answer 4

symptoms are concurrent with major depressive, manic or mixed episode

Question 5

delusional

Answer 5

non-bizarre delusions without other symptoms of psychosis

Question 6

brief psychotic

Answer 6

acute onset of symptoms lasting < 1 month

Question 7

substance-induced psychotic

Answer 7

psychosis within one month of substance intoxication or withdrawal

Question 8

substance use and tobacco use disorders occur in how many schizo patients

Answer 8

50% of schizo patients

Question 9

what is the leading cause of pre-mature death in schizo

Answer 9

suicide

Question 10

what is the schizo gene

Answer 10

C-4

Question 11

dopamine hypothesis

Answer 11

+ symptoms are associated with excessive dopamine transmission

• symptoms are associated with too little dopamine

Question 12

non-genetic prenatal complications

Answer 12

viral infections
poor nutrition
hypoxia
exposure to toxins

Question 13

psychological stressors

Answer 13

childhood sexual abuse
chronic poverty
high crime

stress increases cortisol levels which can cause other issues

Question 14

environmental stressors for schizophrenia

Answer 14

street drugs before age 21

Question 15

DSM-5 schizo diagnosis

Answer 15

2+ of the following for 1 month:

delusions
hallucinations
disorganized speech
disorganized/catatonic behavior
negative symptoms

Question 16

positive symptoms

Answer 16

hallucinations
delusions
disorganized speech
bizarre behavior

acute onset - respond to antipsychotic

Question 17

hallucination types

Answer 17

auditory
visual
tactile
olfactory
gustatory

Question 18

command hallucinations

Answer 18

if they hear it in a familiar voice they are more likely to do it

ask what the voices are telling them to do

Question 19

personal boundary difficulties

Answer 19

depersonalization

derealization

Question 20

delusions

Answer 20

ideas of:

reference
persecution
grandeur
somatic
jealousy
control
thought broadcasting
thought insertion
thought withdrawal

Question 21

associative looseness

Answer 21

flight of ideas

Question 22

clanging

Answer 22

rhyming or sound alike words

Question 23

neologisms

Answer 23

made-up words

Question 24

echolalia

Answer 24

repeated words

Question 25

word salad

Answer 25

mix of meaningless words

Question 26

negative symptoms

Answer 26

affect blunt

Question 27

alogia

Answer 27

poverty of speech and content

Question 28

avolition

Answer 28

no motivatoin

Question 29

anergia

Answer 29

no energy

Question 30

anhedonia

Answer 30

no pleasure

Question 31

poverty of speech

Answer 31

answers briefly

Question 32

thought blocking

Answer 32

interruption in thoughts

Question 33

FGA antagonizes

Answer 33

DA

Question 34

FGA has a greater risk of

Answer 34

EPS

Question 35

SGA antagonizes

Answer 35

serotonin and dopamine

Question 36

SGA has a greater risk of

Answer 36

metabolic syndrome

Question 37

why is SGA harder to get

Answer 37

more costly

Question 38

black box warning for FGA

Answer 38

not approved for dementia-related psychosis

Question 39

which FGA causes QT prolongation

Answer 39

thioridazine

Question 40

common anti-psychotic X10

Answer 40

``` sedation hypotension anticholinergic weight gain photosensitivity sexual dysfunction increased prolactin levels seizures metabolic syndrome EPS ```

Question 41

EPS

Answer 41

akathisia pseudoparkinsonism acute dystonia

Question 42

antiparkinson drugs X4

Answer 42

trihexyphenidyl benztropine dipenhydramine biperiden

Question 43

tardive dyskinesia

Answer 43

serious and irreversible EPS side effect after prolonged treatment symptoms may subside after meds are discontinued or may be permanent

Question 44

AIMS

Answer 44

abnormal involuntary movement scale

Question 45

metabolic syndrome

Answer 45

cluster of conditions that increase risk for heart dz, DM, stroke

Question 46

how is metabolic syndrome diagnosed

Answer 46

``` 3+ of the following obesity HTN hyperglycemia high cholesterol ```

Question 47

Neuroleptic malignant syndrome

Answer 47

rare but potentially fatal SE of antipsychotic

Question 48

symptoms of NMS X9

Answer 48

``` decreased consciousness muscular rigidity increased muscle enzymes hyperpyrexia HTN tachycardia tachypnea diaphoresis drooling ```

Question 49

how to treat NMS

Answer 49

bromocriptine dantrolene IVF