Schizophrenia Flashcards

(36 cards)

1
Q

What can explain why the voices heard by a patient with schizophrenia often know exactly what to say to hurt him/her?

A

Voices become a misinterpretation of patient’s inner feelings
- a worrying thought becomes a negative voice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the earliest and most famous ‘mad house’ in England?

A

Bethlem (Bedlam)

- founded in 1247

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happened in psychiatry with the industrialisation?

A

Psychiatric hospitals were built across Europe and USA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What were the key aspects of asylums during the institutionalisation in the 1800s?

A

Asylums
- should provide good accomodation

  • built in green areas, outside cities
  • provide healthier lifestyle to patients
  • allow patients to recover away from poor living conditions of Victorian cities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What was the reality of asylums during the institutionalisation in the 1800s?

A

Terrible conditions in the original ‘Mad houses’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What was the context of the building of asylums in the first half of the 19th century (1808-1845) in England?

A
  • Most major cities decided to build asylums
  • Movement to try and do the best for those with mental disease
  • Often, quite beautiful buildings
  • Initially good conditions and people were well looked after
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What was the main difficulty in the asylums during the first half of the 19th century in England?

A

Lack of patient recovery

  • remote location of asylums -> hard for relatives to visit patients
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What characterised the deterioration of asylum conditions in the 19th and 20th century?

A
  • Lack of patient discharge
  • Mental hospitals began to get overwhelmed with numbers
  • > conditions deteriorated
  • By 1900s, idea of moral therapy had declined
  • The mentally ill were segregated from rest of population
  • > patients were forgotten by society
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What promoted a better understanding of the differences between patients in mental hospitals in the 1800s?

A

Mental hospitals allowed doctors to be exposed to different types of patients with a wide spectrum of disorders

-> alienists (now psychiatrists) realised there was different types of people with different types of diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What were common mental diseases identified by alienists in the 1800s?

A
  • General paralysis of the insane (illness secondary to chronic syphilis, which caused brain damage)
  • Mental handicap
  • Alzheimer’s disease
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How were Emil Kraepelin and Alois Alzheimer connected?

A

Alois Alzheimer was in Kraepelin’s department in Germany

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What was Dementia praecox?

A

Disease considered by Emil Kraepelin, currently known as schizophrenia

  • he compared it to Alzheimer’s disease
  • key difference was its earlier onset
  • it differentiated from ‘Manic depressive insanity/psychosis’, with a fluctuating course of frequent relapses, but better prognosis
  • worse outcome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Who coined the term schizophrenia in 1911?

A

Eugen Bleuler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What was Eugen Bleuler’s view on schizophrenia?

A
  • Existence of more than one type of schizophrenia
  • More psychological than organic: a neuropathological degenerating disorder
  • 4 A’s: autism, ambivalence, loose associations, blunting or incongruity of affect
  • more optimistic outcome than Kraepelin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What were the four ‘A’s of schizophrenia defined by Eugen Bleuler?

A
  1. Autism: difficulties in social communication
  2. Ambivalence: uncertainty
  3. Loose associations: unusual forms of thought
  4. Blunting or incongruity of affect: in the display of emotions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What the issue with Bleuler’s diagnostic criteria of schizophrenia?

A
  • It was hard to distinguish what the 4 ‘A’s were

- > in the US, there was an emerging over diagnosis of schizophrenia

17
Q

How is the Kraepelinian view of psychosis, modified by Eugen Bleuler, still used nowadays?

A
  • Dementia praecox -> Schizophrenia

- Manic depressive insanity/psychosis -> Bipolar disorder

18
Q

What were Schneider’s first rank symptoms as indicators of schizophrenia?

A
  1. Auditory hallucinations
    - thought echo
    - third-person hallucinations
    - running commentaries
  2. Thought insertion or withdrawal
  3. Thought broadcasting
  4. ‘Made’ acts, thoughts or feelings (via external force that takes over control of the person)
    - seen in acute episodes
  5. Delusional perception
    - delusional meaning given to a perceived thing
19
Q

What was Schneider’s view on Bleuler’s characterisation of schizophrenia?

A

Bleuler’s ideas were too complex for the average psychiatrist to detect reliably

20
Q

What are positive symptoms in schizophrenia?

A

Presence of abnormal phenomena

  • Delusions: fixed false idea, unshakeable, not shared amongst people from same culture
  • Hallucinations: perception when there is lack of stimulus
  • Formal thought disorder: disorganised thinking
21
Q

What are negative symptoms in schizophrenia?

A

Absence of normal behaviour

  • Flat or blunt affect: lack of emotional response
  • Cognitive difficulties
  • Poverty of speech
  • Loss of initiative: lack of motivation for everyday activities (e.g. eating)
  • Self-neglect: lack of care for one’s appearance
  • Social disinhibition: embarrassing or rude behaviour
22
Q

What are the rates variations of schizophrenia according to age and gender?

A
  • Tends to affect young people
  • Unlikely to occur in older people or children
  • Men are most likely to develop psychosis in early 20s
  • Women are most likely to develop psychosis later in life
23
Q

What does the oestrogen theory of later onset of psychosis in women propose?

A

Oestrogen is protective, hence it is unlikely for women to develop psychosis during their reproductive period

24
Q

What did Manfred Bleuler propose on the long-term course of schizophrenic psychoses (1973)?

A
  • “Large number of long-standing schizophrenic illnesses”
  • “On average, schizophrenia showed no further change for the worse after a duration of 5 years, but rather a tendency to improve”
  • > not necessarily a deteriorating disorder
  • > different from Alzheimer’s disease
25
Who was Manfred Bleuler?
- Son of Eugen Bleuler - he would stay with his dad an play with some of the patients - after graduating, he went on to medical school to become a doctor and psychiatrist - he worked and lived at Burgholzli psychiatric clinic in Switzerland
26
What are the five possible outcomes of schizophrenia?
1. One episode only in the lifetime 2. One episode every 2 to 3 years (no symptoms in-between) 3. One episode every 2 years (no symptoms in-between) 4. Several episodes and symptoms continue (no worsening) 5. Several episodes and symptoms continue, accumulate and get worse - accumulation of negative symptoms
27
In a 10 years follow-up of people with schizophrenia, what was observed about the course and prognosis?
- About 40% will have no psychotic symptoms at 10 years (half will be taking medication) - About 40% will have relapses (potential degradation of social/work relationships) - About 20% will go into a chronic form: treatment-resistant
28
What is the traditional Kraepelinian dichotomy?
Psychosis - 'Dementia praecox': true schizophrenia - 'Manic depressive psychosis': true bipolar disorder
29
What is usually observed in real life on the traditional Kraepelinian dichotomy?
Often difficult to tell apart schizophrenia from bipolar disorder - misdiagnosis - schizoaffective disorder in-between the schizophrenia and bipolar
30
What is the issue with diagnosing people with schizophrenia?
It is not welcomed by patients - they often find bipolar diagnosis more positive, with the existence of more available treatment for BD - stigma around schizophrenia due to generalised perception of those diagnosed being dangerous or violent - even though vast majority of people with schizophrenia are not dangerous or violent (concerns mostly those with substance misuse)
31
Why was a dimensional view of psychosis suggested by psychiatrists?
In recent years, dissatisfaction with the diagnosis of schizophrenia - stigma - lack of explanation for its onset and outcome
32
What does the multidimensional approach to the diagnosis of psychosis consist of?
5 factors - Negative symptoms (loss of motivation, cognitive difficulties, self-neglect) - Positive symptoms (delusions, hallucinations) - Manic - Depressive - Disorganisation (thought disorder)
33
What did the SCAN interview study of Demjaha and colleagues (2009) show about psychotic patients?
- 536 first-episode psychotic patients interview with SCAN - Usual five factors identified (negative, positive, manic, depressed, disorganisation), better when describing people and their responses to different treatments - Patient's responses weren't positive enough to justify abolishing previous diagnoses of schizophrenia and bipolar disorder - > Best approach: mix of categorical diagnosis with description of the factors
34
What was the traditional view of schizophrenia?
Discrete categorical disease entity | - 'sane' vs 'insane'
35
What is the emerging view on schizophrenia and psychosis?
Continuum of psychosis - in general population up to 15% might have psychotic symptoms - psychosis is similar to anxiety or depression, in that people experience it at some point in their lives - schizophrenia is severe psychosis - some people are not prone to paranoia - some are in the middle - some have many psychotic symptoms and need treatment
36
What does the psychiatric literature suggest on the view of psychosis?
Psychosis as fluctuating matter, such as weight - in the dimensions, there's a threshold (cut-off point) that makes the diagnosis of schizophrenia - factors that induce psychosis and schizophrenia also induce temporary paranoia or other psychotic symptoms in gen pop - > look at factors within our society that push people into developing psychosis and schizophrenia