Schizophrenia Flashcards

(112 cards)

1
Q

what is schizophrenia?

A

psychosis characterized by abnormalities in perception, content of thought, and thought processes and extensive withdraw of interest from people and the outside world
“splitting of thoughts from emotions and people”

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2
Q

psychosis

A

loosing touch with reality
individual experiencing hallucinations, delusions, disorganized thoughts, speech, or behavior

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3
Q

what is the hallmark sign of schizophrenia

A

delusions, hallucinations, and disorganized speech

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4
Q

schizophrenia interferes with a persons ability to

A

think clearly
manage emotions
make decisions
relate to others

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5
Q

epidemiology of schizophrenia

A

leading cause of disability if diagnosed
most frequently diagnosed in males in urban areas
peek age of onset 15-35
men 15-25
women 25-35
children is uncommon
new cases are rare before age 10 and after 40

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6
Q

etiology of schizophrenia

A

genetics - heredity plays strong role
environmental- malnutrition in 2nd and 3rd trimester can play a part
brain chemistry
substance abuse- mind altering drugs during teen and early adult years can play a part.

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7
Q

comorbidities with schizophrenia

A

substance use disorders
nicotine dependence
anxiety, depression, and suicide
diabetes
cardiovascular disease
obesity
malignant neoplasm
HIV/AIDS
osteoporosis
Hep C

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8
Q

positive symptoms of schizophrenia

A

symptoms that exist but shouldn’t be there
hallucinations
delusions
disorganized behavior
disorganized speech

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9
Q

hallucinations

A

can include the 5 senses
auditory and visual are the most common
auditory- obscene, accusatory, or insulting
visual- usually sees something threatening
tactile
olfactory
gustatory

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10
Q

command hallucinations

A

telling them to do something
auditory hallucination
commands to harm themselves or others
must be carefully monitored
ask: Are you hearing a voice that is telling you to do something?
Do you plan to follow the command?
Do you believe the voices are real?

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11
Q

treating hallucinations

A

-observe for tracking eyes, mutterings, talking to self, distraction, talking and suddenly stopping as if interrupted, intently watching a vacant part of the room
ask about the content of hallucination
*do not refer to hallucinations as if they are real ( do not ask: what are the voices saying to you, instead say What are you hearing?)
-watch for signs of anxiety, these may indicate the hallucinations are intensifying
-do not negotiate with clients hallucinations (I don’t hear the voices that you hear, but it must be frightening for you)
-focus on reality, here and now activities (the voices you are hearing are part of your illness, they cannot hurt you)
-address underlying emotion- fear and guilt (remind them they are safe)
-promote and guide reality testing- ask client to look around and observe if anyone else appears frightened.

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12
Q

teaching for clients with schizophrenia

A

manage stress
use other sounds to compete with hallucinations (radio, tv, reading, etc.)
check with others to find out what is real and not
engage in activities to take your mind off hallucinations
talk (tell self voices are not real, tell voices to go away, tell yourself no matter what you hear you will be safe)
develop a plan to cope with hallucinations

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13
Q

delusions

A

erroneous fix beliefs that cannot be changed by reasonable arguments

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14
Q

grandiose delusions

A

belief that one has exceptional powers

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15
Q

nihilistic deluison

A

belief that one is dead or a disaster is impending

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16
Q

persecutor delusion

A

belief that one is being watched, plotted against, and ridiculed

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17
Q

somatic delusions

A

belief about abnormalities in the body function or structure

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18
Q

religious delsions

A

believe that they have a special relationship with God,, or on a mission from God, or they are sinners

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19
Q

referential delusion

A

believes that newspaper articles, TV shows or song lyrics are directed specifically at them

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20
Q

Treating delusions

A

-establish therapeutic relationship
-respond to suspicion in matter of fact, empathic, supportive and calm manner
-ask client to describe his beliefs (tell me more about someone trying to hurt you)
-never debate the delusional content (although it is frightening to you, it seems that it would be hard for a small girl to hurt you)
-validate if part of the delusion is real (yes there was a man at then nurses station but he was asking for water)
focus on feelings or themes
-use reality based interventions to help meet clients underlying needs (if client believes he is powerful he may really feel powerless)
-acknowledge that while belief seems very real to client, illnesses can make things seem true even though they aren’t
-don’t dwell excessively on the delusion, instead focus on reality-based topics

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21
Q

thought blocking

A

client is talking, and abruptly pauses and cannot remember what they were saying

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22
Q

thought broadcasting

A

“people can read their minds”
clients think people can hear their thoughts or know what they are thinking

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23
Q

thought withdraw

A

people are taking thoughts out of their brains
blames poor memory on government agents who steal their thoughts

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24
Q

thought insertion

A

repeatedly complains of having disturbingly violent thoughts, which she clans are being sent by satan

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25
paranoia
irrational fear, ranging
26
circumstantiality
extremely detailed and lengthy talk about a topic but eventually gets to point
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tangentiality
extremely detailed and lengthy talk but never gets to the point
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loose associations
absence of normal connected thoughts, ideas and topics ( i was home when drum beating began, i flew too low)
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Flight of Ideas
conversation topic changes repeatedly and rapidly with only superficial associative connections ( a man begins talking about his business, but quickly shifts to talking about the economy, government, and other countries)
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echolalia
repetition of another's words, pathological repetition
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clang associations
repetition of works with a similar sound but in no other way ( i heard a bell. well, hell then i fell)
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stilted language
overly and artificially formal language
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pressured speech
words are being forced out
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word salad
string of words totally unconnected, jumbled, meaningless to a listener (because is makes a twirl in life, my box is broken, help me blue elephant)
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neologism
made up words meaning for the patient only ( I got to do angry, I picked up a dish and threw it at the geshinker)
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paranoid disorganized speech
suspiciousness that is unrealistic
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illogicaliy
conclusions are reached that do not follow logic
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aggression
behaviors or attitudes that reflect rage
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agitation
inability to sit still or attend to others, pacing
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catatonic excitement
hyperactivity characterized by purposeless activity and abnormal movements
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catatonia
waxy, hold same position for hours, not just specific to schizophrenia, can be immobile, non-responsive
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echopraxia
involuntary imitations of another's movements and gestures
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regressive behavior
childlike/immature
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stereotype
repetitive purposeless movements that are peculiar to the person
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hypervigilance
sustained attention to external stimuli
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waxy flexiblity
posture held in a flexible position, patient can be posed
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negative symptoms
symptoms that should be there aren't affective flattening or blunting ambivalence- presence of two opposing forces, leading to inaction, cant decide, stuck alogia- poverty of speech avolition- inability to complete projects, assignments, work, loss of motivation anhedonia- loss of pleasure, hijacks joy asociality- decreased desire for social interactions, isolation
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cognitive symptoms
concrete thinking- inability to think abstractly impaired memory- impacts short term memory and ability to learn impaired information processing- delayed responses, misperceptions or difficulty understanding others impaired executive functioning- difficulty with reasoning, setting priorities, comparing options, planning
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prodromal phase of schizophrenia
mild changes in thinking insufficient to meet DSM 5 criteria for schizophrenia symptoms appear 1 month to more than 1 year before full blown episode speech and thought may be odd or eccentric anxiety, obsessive thoughts, and compulsive behaviors deterioration in concentration distressing thoughts, suspiciousness, memory impairment, significant disorganization in speech
50
Acute phase of schizophrenia
later symptoms from few and mild to many and disabling symptoms include hallucinations, delusions, apathy, social withdraw, diminished affect, anhedonia, disorganized behavior, impaired judgement, and cognitive regression difficulty coping as symptoms worsen symptoms that were once concealed become apparent hospitalization required men late adolescents 15-25, women 25-35
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stabilization phase of schizophrenia
symptoms are stabilizing and diminishing movement toward a previous level of functioning
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maintenance or residual phases of schizophrenia
condition has stabilized new baseline established positive symptoms are usually absent or significantly diminished but negative symptoms continue to be a concern
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relapse with schizophrenia
can occur at any time during treatment detrimental to the successful management with each relapse takes a longer time to recover combining meds with psychotherapy diminishes the severity and frequency of relapses major reason for relapse is nonadherence with meds stopping meds will certainly lead to relapse
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is there a cure for schizophrenia?
no cure but can recover!
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schizophrenia and violence
violence is a risk for those not medicated and experiencing command hallucinations and/or who have a substance abuse or alcohol abuse problem
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schizophrenia and suicide
suicide attempts are common within 3 yrs of diagnosis more common upon discharge following first episode
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risk factors of suicide and schizophrenia
depressive symptoms young age at onset absence of supportive friends and family
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schizophrenia and mortality rate
higher mortality rate from accidents and medical illnesses (die at younger age because they dont take care of their physical health) high rates of smoking wt gain with neuroleptic meds can cause metabolic syndrome, type 2 DM, and cardiac problems
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late signs and symptoms of schizophrenia
hallucinations with auditory delusions lack of emotion emotions are inappropriate social withdraw poor school performance decreased ability to practice self care strange eating rituals incoherent speech illogical thinking agitation
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anitpsychotics treat
severe thought disorders such as schizophrenia and bipolar acute and chronic confusion psychosis, extreme aggression, and dementia
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target symptoms that antipsychotics treat
disorganized thinking, speech, and behavior flat or inappropriate affect delusions hallucinations catatonia
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treatment goals of schizophrenia
safety in all settings stabilization on antipsychotic client and family education physical care psychosocial support
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failure to take prescribed meds can result in
risk of relapse risk of suicide increased mortality rates potential for hospital readmission declined quality of life social and occupational difficulty
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antipsychotic meds are essential to treat
symptoms during both acute and long term phases of illness
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what does early intervention with meds do for schizophrenia?
decreases some associated long term co-morbid, co-existing conditions
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typical antipsychotics
chlorpromazine (thorazine) haloperidol (haldol)
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side effects of typical antipsychotics
anticholinergic sedation EPS hypotension seizure photosensitivity skin rash GI upset EKG changes hormonal/endocrine agranulocytosis neuromalignant syndrome tardive dyskinesia Liver impairment prolonged QT
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first generation typical antipsychotics
D2 receptor agonist target positive symptoms of schizophrenia less expensive than second generation disadvantages: EPS, Anticholinergic side effects, tardive dyskinesia, WT gain, sexual dysfunction, endocrine disturbances
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anosognosia
inability to realize they are ill may cause resistance to treatment plan or cessation of treatment combined with paranoia so that accepting help is impossible
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anticholinergic side effects
hot as a hare dry as a bone red as a beet mad as a hatter
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Extrapyramidal Symptoms
psudoparkinsonism akathisia actue dystonia tardive dyskinesia usually start within a few weeks of starting antipsyhotics symptoms may cause discomfort, social stigma, and poor compliance
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psudoparkinsonism
simulates parkinsons disease is reversible and includes tremors in hands and arms bradykinesia, akinesia, hypersalivation, masked faces, and shuffling gate
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treatment of psudoparkinsonism
dose reduction or addition of oral anticholinergic med
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Akathisia
inner restlessness manifested by excessive pacing or inability to remain still for any length of time
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treatment of akathisia
dose reduction of antipsychotic or addition of low-dose beta blocker, such as propranolol (inderal)
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dystonia's Extrapyramidal side effects
dystonic reactions caused by antipsychotics need to be monitored for and acted on emergently torticollis, oculogyric crisis, opisthotonus, laryngospasm, oral-facial maxillary spasm
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torticollis
spasmodic and painful spasm of muscles (head pulled to one side)
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ocylogyric crisis
eyes roll back, only white visible emergency situation
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opisthotonus
a type of spasm om which the head and heels arch backward in extreme hyperextension and the body forms a reverse bow
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laryngospasm
spasm of throat impairing breathing and swallowing
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oral-facial maxillary spasms
treat emergently as the may progress (resembles bells palsy)
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treatment for mild side effects of EPS
reduce dosage d/c med- taper them off switch to another med in same class- one is tapered down while one is tapered up add an anticholinergic- benztropine (Cogentin), diphenhydramine (Benadryl), trihexyphenidyl (atrane) sometimes anticholinergics are given with antipsychotics to reduce likelihood of EPS add beta blocker- propranolol
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tardive dyskinesia
involuntary movement that can occur with long term antipsychotic treatment and may not be reversible even when med discontinued usually involves orofacial region, can include myoclonic jerks, tics, chorea, dystonia, symptoms become more evident when patient is aroused, and ease when pt is relaxed or disappear during sleep attempts to treat TD usually begin with discontinuing the offending agent or switch to one with lower risk
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risk factors for developing tardive dyskensia
long term therapy with FGA's at higher doses older age female concurrent affective disorders
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late onset tardive dyskinesia
after many years of antipsychotics often permanent dysfunction of voluntary muscles effects mouth (tongue protrudes, smacking of lips, mouth movements) routinely evaluate client on AIMS scale changes may be gradual or mild and slowly progress, providers can miss signs often irreversible important to catch early
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treating tardive dyskinesia
depends on severity, med may be discontinued thorough exam and documentation of symptoms use AIM scale close and continued follow up clozapine (Clozaril) has shown efficacy in symptom reduction
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new medication for TD
avobenzone
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NMS: neuroleptic malignant syndrome
serious and potentially fatal usually associated with antipsychotics ( or drugs that block dopamine receptors) dehydration is predisposing factor more common in warm climates may have genetic predisposition
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signs and symptoms of NMS
fever 103-105 diaphoresis muscle rigidity: arm/abdomen board like with corresponding increase in CPK levels labile BP swings from hypo to HTN tachycardia >130 Tachypnea >25 agitation r/t respiratory distress mental status changes; stupor/coma
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interventions for NMS
stop all antipsychotics symptomatic; supportive treatment hospitalization required
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drugs to treat NMS
dantrolene (dantrium) bromocriptone (parlodel) levodopa lorazepan (ativan) 10% fatality rate difficult to diagnose in emergent situation
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atypical antipsychotics second generation
treat both positive and negative symptoms minimal to no EPS disadvantages- tendency to cause significant weight gain, risk of metabolic syndrome
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atypical antipsychotics
clozapine (clozaril) olanzapine (zyprexa) respiridone (respiradol) respiradol consta ziprasidone (geodon)
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third generation antipsychotic meds
subset of second dopamine system stabilizers may improve positive and negative symptoms and cognitive function little risk of EPS or TD aripiprazole (abilify) brexpiprazole (rexulti) caripazine (vraylar)
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side effects of atypical antipsychotics
sedation n/v- usually stops after 2 weeks less likely to cause anticholinergic effects, orthostatic hypotension, seizures, EPS more likely to cause major weight gain, changes in person metabolism leading to DM, hypoprolctinemia potential for cardiac dysrhythmias/ even sudden cardiac death rhinitis sexual dysfuntion more costly than antipyschotics
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metabolic syndrome
special concern with atypical antipsychotics heart disease, lipid problems, HTN, type 2 DM, dementia, cancer, PCOS, Non-alcoholic fatty liver disease monitor wt and girth, initial glucose tolerance test, monitor glucose, provide nutritional support and activity support, consider lifestyle changes
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clozaril
treats refractory schizophrenia or schizophrenia that doesn't respond to normal tx pts with refractory are prone to violence and suicide med results in decreased negative symptoms, increased pulse control, reduced violence to self harm and others, improved quality of life has potentially fatal side effect of agranulocytosis
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agranulocytosis
low production of granulocytes body cannot fight off infection WBC drops dangerously low monitor WBC weekly for first 6 months, then every other week discontinue Clozaril if WBC falls below 3000 or granulocytes fall below 1500 reversible if treated early
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parenteral drugs
for patients that are severely disturbed or present serious compliance risk also available in injectable form long acting only require administration once every 2 to 4 weeks fluphenazine decanoate haloperidol decanoate risperidone microspheres paliperidone palmitate olanzapine long acting injectable aripiprazole microspheres
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Long Acting Anti-psychotics meds
long lasting 2 weeks haloperidol (Haldol decanoate) risperidone (consta) paliperidone (Invega Sustenna)
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implications for Long acting anti-psychotic meds
schizophrenia bipolar 1 and those unable to adhere to treatment be aware of patients travel/transportation, cognitive deficits, lack of social support * must have transportation to receive injection
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paliperidone palmitate (Invega Trinza)
3 month injection atypical antipsychotic for schizophrenia after successful treatment with Invega Sustenna (1 month injections) for at least 4 months
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Dissolvable anti-psychotic meds
olanzipine (zydis) risperidone ( Risperdal M-tab) asenapine (saphris) indicated for severe agitation, inability to follow directions on how to take me, or inability to swallow tablets
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Toxins affecting efficacy of anti-psychoitc meds CANS
Caffeine alcohol nicotine sugar
105
additional schizophrenia treatments
ECT behavior therapy group therapy family therapy social skills training case management support groups
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prognosis of schizophrenia
for most symptoms improve with meds and psychosocial interventions can experience good quality of life, family and occupations sometimes does not respond fully to tx leaving mild to severe residual symptoms and varying degrees of dysfunction/disability
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factors that require repeated or lengthy inpatient care
slow onset of disease (more than 2-3 yrs) younger age at onset longer duration between first symptom and first treatment longer periods of untreated illness more negative symptoms
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dichotomous
often seen in borderline personality disorder tend to perceive and evaluate every thought or situation as black or white, good, or bad, all or nothing. unable to see grey areas
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perservation
persistent repetition of words or ideas
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racing
does not just mean thinking fast. Thoughts wont be quiet ; they can be in the background of other thoughts or take over a persons consciousness; they can gallop around in the persons head like a carousel gone out of control
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referential
belief that neutral, everyday occurrences carry specific personal meaning to the individual. Varies in intensity. may be seen in someone with schizoaffective disorder
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Alogia
Poverty of speech