Schizophrenia

Question 1

what is schizophrenia

Answer 1

psychotic syndrome identified by characteristic cluster of symptoms that last for certain time.
-neural disconnection & includes group of illnesses diverse in nature.

Question 2

what is the peak onset age for schiz

Answer 2

Men=21-26 years
women= 25-32 years

Question 3

how many years is life expectancy reduced by

Answer 3

12 years due to cardiovascular disease, 10% complete suicide

Question 4

causes of schizo

Answer 4

-Migration, infections, viruses and toxins
-family history
-lifetime risk in gen population = 1%, 6.5% in 1st degree relative & 40% monozygotic twins of affected people

Question 5

difference between typical & atypical

Answer 5

typical = treat positive symptoms, 1st gen & targets dopamine exclusively

atypical= 2nd gen, target dopamine, serotonin (5HT) & alpha2

Question 6

Schiz vs Parkinson

Answer 6

schizo=high dopamine so give dopamine blockers
parkin= low dopa so give dopamine