Schizophrenia Flashcards

(58 cards)

1
Q

% of homeless people with schiz.

A

10-20%

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2
Q

Age of onset

A

16-25

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3
Q

Suicide rates

A

8-10%

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4
Q

Amount of canadian

A

300,000– 1/12 of hospital beds

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5
Q

Costs

A

6.85 billion

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6
Q

% of patients with auditroy hallucinations

A

70%

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7
Q

Postive Symptoms

A

Exaggerated, distorted adaptations of normal behaviour– delusions, hallucinations, disorganized thought and speech

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8
Q

Negative Symptoms

A

Absence of typical behaviours and experiences

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9
Q

Avolition

A

Apathy and loss of motivation

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10
Q

Anhedonia

A

Inability to feel pressure and lack of emotional response

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11
Q

Hallucinations

A

Misinterpretations of sensory perceptions that occur while a person is awake and conscious, and in the absence of corresponding stimuli

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12
Q

Delusions

A

Implausible beliefs that persist despite contradictory evidence

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13
Q

Persecutory Delusions

A

Believe they are being pursued or targeted– most common

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14
Q

Referential delusions

A

Belief that common, meaningless occurances have significant and personal relevance

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15
Q

Somatic delusions

A

Related to patient’s body– organs have turned to dust

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16
Q

Religious delusions

A

Belief that biblical passages offer the way to destroy or save the world

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17
Q

Delusions of grandeur

A

Belief in divine or special powers that can control the course of history

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18
Q

Loose Associations

A

Shifts quickly from one topic to another

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19
Q

Word salad

A

Many different, unrelated topics

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20
Q

Neologisms

A

Newly created word whose meaning is unknown to others

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21
Q

Perseveration

A

Repetition of the same verbal or motor response

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22
Q

Thought blocking

A

Sudden silences in persons speech

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23
Q

Abnormal motor behaviour

A

Deficits in motor functioning and difficulty with goal directed behaviour

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24
Q

Catatonic behaviour

A

Reduction n responsiveness to environment

25
Wavy flexibility
Allowing others to move their body into new positions and maintaining it
26
Affective flattening
Lack of emotional responsiveness and failing to convey feeling
27
Alogia
Poverty of speech
28
6 DSM criteria
Characteristic symptoms Social or occupational dysfunction Persistence for at least 6 months Exclusion of schizoaffective or mood disorders Exclusion of substance abuse or medical conditions Consideration of autism or communication disorder
29
3 phases of schiz
Prodromal Active Residual
30
Prodromal
Clear deterioration of functioning
31
Active
2 or more symptoms, one must be positive, lasts at least 1 month
32
Residual
Attenuated symptoms following active phase
33
Schizophreniform disorder
Lats 1-6 months
34
Brief psychotic disorder
Less than 1 month
35
Endophenotypes
Hereditary marker that is closely associated but is not a direct symptom of disorder-- vulnerability
36
Cognitive subtypes
Subgroups on basis of impaired problem solving and memory deficits
37
Kraepelin
Noted it ran in families, frontal and temporal lobes involved
38
Schizophrenogenic
Cold and rejecting behaviour causes schizophrenia
39
Collective unconcious
Jung-- Symbols and myths are shared unconsciously in a culture
40
Hypokrisia
Nerve cells are abnormally reactive to incoming stimulation
41
Aversive drift
Brain amplifies feelings of pain and weakens pleasure-- makes social contact unpleasant
42
Schizotype
Person experiencing cognitive slippage and aversive drift
43
One episode only, complete recovery
20%
44
Several episodes, return to normal functioning
35%
45
Several episodes, never return to normal
10%
46
Continual deterioration, poor er functioning between episodes
35%
47
Reducton in lifespan
10 years
48
Prevalence
1% men= women
49
Schizoaffective disordr
Grandiose, jealous, persecutory
50
MZ concordance rate
48%
51
Penetrance
Proportion of peoplewith a genetic change that exhibit signs of a disorder
52
Cumulative liability
Combined risk for developing an illness that accumulates over multiple factors and over time
53
Left temporal lobe
Attention, speech, language, visual understanding
54
3 systems in dopamine hypothesis
Nigrostriatal Mesocortical Mesolimbic
55
D2 receptors
Postive symptoms, benefit from antipsychotics
56
D1
Negative symptoms
57
Basal ganglia
Abnormal motor behaviour
58
Right temporal lobe
Flat affect, aprosodia