Schizophrenia

Question 1

Antischizophrenic drugs are particularly effective against..

Answer 1

positive symptoms

Question 2

Haloperidol is a potent

Answer 2

D2 ligand, neuroleptic, antischizophrenic drug

Question 3

What were the first antischizophrenic drugs?

Answer 3

chlorpromazine an reserpine

Question 4

Halperidol is what kind of drug?

Answer 4

phenothiazine

Question 5

What do phenothiazine’s do?

Answer 5

bind to D2 and D1 receptors

Question 6

What is a Butyrophenones?

Answer 6

a drug that only binds to D2 receptors

Question 7

what defines an atypical neuroleptic?

Answer 7

a drug that is affective against SZ without binding strongly to D2 receptors

Question 8

What drug have an affinity for D1, D4 and serotonin receptors?

Answer 8

Clozapine

Question 9

What do effective drugs block?

Answer 9

glycine of glutamate

Question 10

Is Chloropromaizine an antagonist or an agonist?

Answer 10

antagonist: it increases extracellular levels of metabolits

Question 11

what was frist developed as a antihistamine?

Answer 11

chloropromazine

Question 12

What does Reserpine do?

Answer 12

depletes the brain of dopamine