Schizophrenia Flashcards

(33 cards)

1
Q

What is the definition of psychosis?

A

Lack of insight leading to inability to destinguish real life from delusion/hallucination

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2
Q

What are the 3 core aspects of schizophrenia?

A

Thinking

Behaviour

Emotion

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3
Q

What can schizophrenia’s symptoms be divided into?

A

Positive

Negative

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4
Q

What are the positive symptoms of schizophrenia? positive = gives the patient something

A

Hallucination
Delusion
Disordered thinking

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5
Q

What type of hallucination is the most common?

A

Auditory

Tactile slightly less

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6
Q

What are the negative symptoms of schizophrenia? negative = takes away

A

Apathy

Lack of interest

Lack of emotion

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7
Q

What are the 4 core ICD-10 symptoms of schizophrenia

A

Alienation of thought

Delusions of control

Hallucination

Persistent delusion

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8
Q

What does alienation of thought mean?

A

Either

  • Thought broadcasting
  • Thought insertion
  • Thought echo
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9
Q

What are delusions of control?

A

That someone else has control of your body/actions

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10
Q

How are persistent delusions defined?

A

Delusions that are culturally innapropriate or totally impossible

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11
Q

What are the 4 additional ICD-10 symptoms of schizophrenia?

A

Persistent hallucination

Neologisms

Catatonic behaviour

Negative symptoms

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12
Q

What is considered “persistent hallucination”

A

Hallucinations every day for 1 month

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13
Q

What are neologisms?

A

Breaks/sudden changes in thought

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14
Q

What do neologisms lead to in conversation?

A

Lots of cuts from speech topics

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15
Q

What catatonic behaviour may be seen in schizophrenia?

A

Negatism

Waxy flexibility

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16
Q

What is waxy flexibility?

A

Like flexed limbs constantly

17
Q

What is the ICD-10 requirement for diagnosis?

A

1 core symptom + 2 additional symptoms for 1 month

18
Q

Mnemonics for core and additional symptoms?

A

ADHP
- “Not ADHD but ADHPsychosis”

PNCN
- Practice nothing contribute nothing

19
Q

What are 6 types of schizophrenia?

A
Paranoid
Hebephrenic
Catatonic
Undifferentiated
Residual
Simple
20
Q

What are genetic causes of schizophrenia?

A

Neuregulin mutation
Dysbindin mutation
DiGeorge syndrome

21
Q

What are physical causes of schizophrenia?

A

Dopamine hypothesis

22
Q

What is the dopamine hypothesis?

A

Excess dopamine may lead to schizophrenia

23
Q

What psychological principle may explain the cause of schizophrenia?

A

Gestalt psychology

24
Q

What is gestalt psychology?

A

A state of fear causes a delusion to allow the brain to make sense of it leading to a breakdown

25
DDx of schizophrenia?
Schizoaffective disorder Delerium Organic cause
26
What is 1st line treatment?
CBT + antipsychotics
27
What are some first line antipsychotics?
Risperidone Aripiprazole Olanzapine
28
What drug can be used in treatment resistant schizophrenia?
Clozapine
29
What drugs can be used if there is cognitive decline?
Cholinesterase inhibitors
30
What drugs can be used for the negative symptoms of schizophrenia?
SSRI | SNRI
31
What is first line mood stabiliser in negative symptom treatment of schizophrenia?
Lamotrigine
32
What are good prognostic indicators?
Negative FH Good premorbid personality Acute onset with prompt treatment
33
Bad prognostic factors?
+FH | Slow onset