Schizophrenia and treatment Flashcards

1
Q

define dementia praecox.

A

krapelin - meaning senility of the young.

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2
Q

according to krapelin, sufferers exhibited…

A
  • intellectual impairment
  • problems of attention and memory
  • hallucinations and delusions
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3
Q

who coined the term ‘schizophrenia’?

A

Bleaular

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4
Q

outline the DSM-5 diagnosis for schizophrenia.

A
2 or more...
- delusions 
- hallucinations 
- disorganised speech 
- grossly disorganised 
- negative symptoms 
Deterioration of work, relationships or self-care.
At least 6 months.
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5
Q

name disorders associated with distressing voices.

A
  • schz 70%
  • bipolar
  • PTSD
  • DID
  • BPD
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6
Q

name the prevalence of schz

A
  • population 1:100
  • one parent with schz 10:100
  • both parents 45:100
  • only 11% have one or more parent with schz, 37% of cases have no relative with schizophrenia
  • onset earlier for men (20-24 years) than females (25-29 years).
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7
Q

state ‘further treatments’ of schizophrenia in the past.

A
  • long bath
  • sedation
  • insulin coma to produce seizure
  • ECT
    medication
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8
Q

state the five myths of schizophrenia.

A
  1. delusions and voices are meaningless symptoms of schz
  2. if you hear voices or hold delusional beliefs you have schizophrenia
  3. schz makes people violent
  4. medication is the solution
  5. people don’t recover from schz.
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9
Q

give evidence that delusions are meaningful.

A
  • reflective themes
  • protective of low self-esteem
  • maintained by normal babies in information processing
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10
Q

give evidence that voices are meaningful.

A
  • common for trauma cases
  • reflective of opinion about selves
  • similar to interpersonal encounters in the ‘real world’.
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11
Q

give evidence against the myth that ‘if you hear voices, you have schz’

A
  • 71% of people without diagnosis heard someone call name, 30% whilst falling asleep, 5% conversation with the dead.
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12
Q

what percentage of the population experience hallucinations?

A

11%.

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13
Q

does schizophrenia lead to violence?

A
  • majority do not engage in violence, more likely to be the victim.
  • diagnosis is associated, however, with risk of criminality and violence.
  • exacerbated by substance misuse.
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14
Q

give evidence that medication is not the solution.

A

up to 74% of patients discontinue medication over 18 months due to distressing side effects.

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15
Q

one alternative to medication os CBT, what does CBT involve?

A
  • listening, curiosity, making sense
  • playing detective and working with evidence
  • assessing self-esteem
  • choice between medication and therapy.
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16
Q

give possible solutions to the challenges of psychological services.

A
  • therapy that requires less resources (less than 16 sessions, group approaches).
  • simpler therapies targeting a specific problem that maintains psychotic experiences e.g. paranoid delusions, distressing voices.
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17
Q

name problems to psychological therpay.

A
  • not enough expert therapists (use APs!)

- long-term process

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18
Q

true or false: people do not recover from schz.

A

false - up to 70% improvement in some cases.

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19
Q

schz is the result of a complex interaction between thousands of genes and multiple env factors, state common causes in combination.

A
  • genetic predisposition
  • child neglect
  • dysfunctional families
  • bullying
  • heavy, cannabis use
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20
Q

give the four explanations of schz.

A
  • psychological
  • psychiatric
  • social
  • political
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21
Q

give the two types of beliefs involved in schizophrenia.

A
  • personal and cultural
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22
Q

what is the concordance rate for individuals with one parent with schizophrenia?

A

9.35%.

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23
Q

name the model the combines genetic and env factors.

A

stress-vulnerability (diathesis) model.

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24
Q

criticise twin studies.

A
  • Mz twins are always the sane sex, unlike Dz twins
  • Mz are usually physically identical so likely to be treated more alike.
  • Mz twins more likely to have shared placenta
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25
Q

give evidence that factors other than genetics play a role in schz .

A

17.4% of children of a Mz twin with no diagnosis are diagnosed, compared to 16.8% of children of a Mz with a diagnosis.

26
Q

women with a diagnosis are more likely to experience complications due to…

A
  • poor prenatal care
  • higher rates of smoking, alcohol and substance misuse
  • poverty
27
Q

how can family problems maintain schz?

A
  • the way they talk about the person with schz e.g. high criticism, hostility or over-involvement, low EE = low relapse.
28
Q

outline the cognitive model of caregiving.

A
  • if positive = no blame + offer support = low EE + see ind beyond problems
  • over-involved = no blame + return to parenting = high EE + excessive caring
  • critical = blame + no support = high EE + angry, rejecting and hopeless.
29
Q

state the two discrepancies.

A

ideal self and actual self.

30
Q

give examples of safety behaviours.

A
  • going out only at night
  • keeping hood up, eyes down
  • leaving any situation with threat.
31
Q

name problems of safety behaviours.

A
  • negatively reinforce diagnosis

- preventing the processing of any disconfirmatory evidence (confirmation bias)

32
Q

state the two types of stigma.

A

public and self-stigma.

33
Q

self-stigma is associated with…

A

increased symptom severity and depressive symptoms, reduced insight and social functioning.

34
Q

name the aspects to the insight paradox.

A

higher insight
higher self-stigma
lower quality of life

35
Q

state the five P’s of CBT formulation.

A
  • presenting (problems)
  • precipitating (triggers)
  • perpetuating (continuing problem)
  • predisposing (what started it)
  • protective (strengths)
36
Q

state the top half of the CBT model.

A
  • multiple experiences of rejection and alientation
  • I am worthless and unloveable
  • does go out and has some friends
37
Q

state the bottom half of the CBT model.

A
  • gradual build-up of stressors
  • I don’t belong anywhere/ people are judging me
    = sad and lonely + stay at home
38
Q

outline the two processes of recovery from psychosis.

A

sealing over - lack of curiosity, negative evaluation of self, ‘get of with life’.
integration - connections, leads to higher quality of life (better recovery), ‘look into it, sort it, then get on with life’.

39
Q

CBT aims to…

A
  • promote understanding of psychosis
  • reduce distress and disability
  • promote more positive responses
40
Q

what does psychosis effect?

A
  • thoughts
  • physical reactions
  • behaviours
  • moods
  • environment
41
Q

what six things do psychological models view delusions as?

A
  • on a continuum with normal beliefs
  • multidimensional
  • attempts to make sense of anomalous experiences
  • mediated by appraisals
  • involve reasoning and attributional biases
  • influenced by emotional processes
42
Q

what can delusions cause?

A
  • conviction
  • preoccupation
  • distress
43
Q

name key factors to working with clients.

A
  • engagement
  • shared goals
  • take client seriously
  • facilitate intervention
44
Q

state CBT approaches

A
  • normalising
  • plausible alternatives
  • reframe appraisals and address biases
  • address emotions
45
Q

outline the cognitive model of the positive symptoms of psychosis.

A
  • bio-psycho social vulnerability
  • trigger
  • emotional changes
  • basic cognitive dysfunction
  • appraisal of experience as external
  • positive symptoms
46
Q

appraisal is influenced by…

A
  • reasoning and attributional biases
  • dysfunctional schemas of self and world
  • isolation and adverse environments
47
Q

state possible issues for clients.

A
  • negative thoughts about therapist, self, the therapy, impacts mood and behaviour
48
Q

state possible issues for the therapist.

A
  • engagement/ flexibility
  • working on thinking biases
  • normalise voices/ anomalous experiences
49
Q

what is the mean effect size on positive symptoms?

A

0.4

50
Q

define PANSS

A

postive and negative syndrome scale

51
Q

state symptoms that are known as positive symptoms.

A
  • delusions, hallucinations
52
Q

stat internal and external conditions of the clients concept of recovery.

A

internal - healing, hope, empowerment, connections

external - human rights, recovery orientated services, positive value of hearing.

53
Q

name a difference between CBT priorities and general recoverys.

A

CBT prioritises ways of dealing with unpleasant experiences whereas general recovery just involves the client to feel a sense of being in control.

54
Q

name types of CBT interventions.

A
  • general formulation
  • group-based
  • intensive and targeted
55
Q

outline the threat anticipation model.

A
  • trigger
  • internal and external events
  • search for meaning
  • persecutory threat belief
  • emotion and reasoning
56
Q

how is worry monitored.

A
  • amount of time, triggers and what helped

- work towards goal

57
Q

state how worry is normalised.

A
  • we all do it
  • takes up time
  • can feel necessary
  • peaks at certain times of the day
  • can be about anything
  • leaves us feeling unsafe
58
Q

name positive beliefs to worry.

A

“to remain organised”
“sort my mind out”
“prevents bad things from happening”

59
Q

outline the worry cycle.

A
  • feeling under threat - positive belief - worry - dwell on the worst possible events
60
Q

give an intervention for worry.

A
  • worry periods

- boosting worry periods and other activities e.g. thinking of something positive