Screening Flashcards

1
Q

Why is screening classed as a cyclical process?

A

People who have a negative test result or who are found not to have the disease are screened again at a later date to check whether they develop the disease at a later date

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2
Q

What is the definition of a true negative?

A

Absent disease + negative test result

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3
Q

Absent disease + positive test result = ?

A

False positive

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4
Q

Present disease + negative test result = ?

A

False negative

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5
Q

What is a true positive?

A

Disease present + Positive test result

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6
Q

How is sensitivity calculated?

A

True positive / (True positive + False negative)

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7
Q

How is specificity calculated?

A

True negative / (False positive + true negative)

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8
Q

True positive / (True positive + false positive) = ?

A

Positive predictive value

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9
Q

True negative / (False negative + True negative)

A

Negative predictive value

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10
Q

‘The proportion of people with the disease who are identified as having it by a positive test result’

A

Sensitivity

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11
Q

The proportion of people without the disease that are reassured by a negative test result

A

Specificity

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12
Q

What is the positive predictive value?

A

The probability that a person with a positive test result actually has the disease

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13
Q

What is the negative predictive value?

A

The probability that a person with a negative test result does not actually have the disease

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14
Q

What are the characteristics of high sensitivity testing?

A

Maximises identification of disease
Low false negatives
High false positives

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15
Q

What are the characteristics of high specificity testing?

A

Detect only people with the disease
Low false positives
High false negatives

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16
Q

What is the lead time basis?

A

a new factor when comparing, in detection of disease, a traditional test with a new or experimental test but the outcome of the disease is unchanged

17
Q

When devising a new screening programme, what are some requirements of ‘the condition?’

A

Must be fully understood
Must have a latent or asymptomatic phase
Must be an important problem
Most have a detectable factor

18
Q

When devising a test for a new screening programme, what are some requirements?

A

Simple, safe, precise and valid
Easily done
Suitable cut off level
Distribution should be known

19
Q

When devising a treatment for a new screening programme, what are some requirements?

A

Treatment or intervention must be effective
Evidence that the outcome is better with treatment
Treatment should be appropriate