Screening and Detection of MDR Bacteria

Question 1

Emergency Surgeries

Primary focus

Answer 1

Primary focus is to stabilise patients and address life-threatening conditions immediately

Question 2

Rapid Diagnostic Tests (RDTs)

Definition

Answer 2

Designed to detect specific diseases, pathogens or health markers quickly. within minutes to few hours
E.g covid-19, blood glucose, HIV test

Question 3

MRSA Screening

Current testing techniques

Answer 3

Swab cultures - time consuming
PCR - expensive

Question 4

MRSA Screening: LGX

Answer 4

Give results within half an hour
In the presence of staphylocoagulase (which is present in MRSA), the substrate mimic or tripeptide from the chromophore is cleaved resulting to a coloured rhodamine fluorophore as it will be released

Question 5

MRSA Decolonisation Protocol

Answer 5

Five day treatment using body wash / shampoo containing Chlorhexidine
Nasal ointment - bactroban (containing mupirocin), prontoderm (containing antibiotic polyhexanide), naseptin (containing neomycin and chlorhexidine + peanut oil)