Screening & Prevention Flashcards

Screening, prevention, diagnostic test, gold standard, sensitivity, specificity, predictive values

1
Q

Screening is what type of prevention?

A

Secondary prevention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which level of prevention aims to reduce the incidence (i.e. the number of NEW cases) of disease by controlling for specific causes and/or known risk factors of disease (typically through prevention strategies?

A

Primary prevention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which level of prevention aims to reduce the prevalence (i.e. the total number of cases) of disease or the more serious consequences of disease through early detection, diagnosis and treatment?

A

Secondary prevention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which level of prevention aims to improve the health outcome for those who already have the disease, i.e. minimise suffering and disability?

A

Tertiary prevention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which test represents the ‘truth’ because they are the best available and most accurate under reasonable conditions?

A

Gold Standard Tests.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is it called when there is a correct positive result for a test, i.e. the person has the disease?

A

True positive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is it called when there is an incorrect positive result for a test, i.e. the person was incorrectly diagnosed with the disease but is actually disease-free?

A

False positive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is it called when there is a correct negative result for a test, i.e. the person does not have the disease?

A

True negative.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is it called when there is an incorrect negative result for a test, i.e. the person was incorrectly diagnosed as disease-free but actually has the disease?

A

False negative.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which test tells us the true positive rate?

Why?

A

Sensitive test.

Sensitive tests have the ability to detect people with the disease correctly. They can sometimes pick up some people with the disease who falsely test negative. In sensitive tests, we can be sure that if someone has a negative result they do not have the disease.

Remember SN N OUT.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which test tells us the true negative rate?

Why?

A

Specific test.

Specific tests have the ability to determine those who do not have the disease. They can sometimes pick up people who do not have the disease but falsely test positive. In specific tests, we can be sure that if someone tests positive, they do have the disease.

Remember SP P IN.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How do you calculate the sensitivity?

A

SN = TP / (TP + FN)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do you calculate the specificity?

A

SP = TN / (TN + FP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which value represents the probability that a person with the disease has a positive result in the test?

A

Positive predictive value.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which value represents the probability that a person without the disease has a negative result in the test?

A

Negative predictive value.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How do you calculate the positive predictive value?

A

PPV = TP / (TP + FP)

17
Q

How do you calculate the negative predictive value?

A

NPV = TN / (TN + FN)

18
Q

The systematic error of apparent increased survival from detecting disease in an early stage is called?

A

Lead time bias.

19
Q

The systematic error from detecting disease with a long latency or pre-clinical period?

A

Length bias.

20
Q

Raw statistics can make screening appear to increase survival time. If the person dies at a time in life that previously has been the usual course of the disease than when detected by early screening, the person’s life has not been prolonged. What type of bias is this?

A

Lead time bias.

21
Q

The perception that screening leads to better outcomes when in reality it has no effect. What type of bias is this?

A

Length bias.