(SDL) Interpreting test results Flashcards Preview

12. CP - Diseases of the Hepatobiliary system and Pancreas > (SDL) Interpreting test results > Flashcards

Flashcards in (SDL) Interpreting test results Deck (6)
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What are the contents of a lab report?

- demographic details from request
- results from lab analysis
- references ranges from scientific knowledge
- comments and advice from experience (human and computer knowledge bases)


List strategies to improve test

- select a more 'normal' population
- use a combination of tests (eg. LFT profiles)
- combine tests to achieve a diagnostic goal eg. neonatal screening for PKU and hypothyroidism
- sensitive first line test (low cost)
- specific test for screen positives (higher cost)


What are the appropriate 'normal' populations?

- patients with similar presenting symptoms eg. chest pain
- same age
- same gender
- hospitalised 'normals'
- same underlying disease


List some factors that affect reference ranges

- age
- gender
- diet
- pregnancy
- time of month
- time of day
- time of year
- weight
- stimulus

(must bear in mind when interpreting results)


Glycosylation of protein leads to what?

Advanced glycosylated endproducts (AGE)
- non-enzymatic process
- rate of formation proportional to glucose concentration and time
- may explain long-term compilations of diabetes


What is HbA1c?

Stable glycosylated haemoglobin
- its percentage concentration indicated cumulative glucose exposure