Second

Question 1

AEDs

Answer 1

antiepileptic drugs

Question 2

gingival hyperplasia is associated with what drug?

Answer 2

phenyltoin

Question 3

Indication for carbamazepine

Answer 3

monotherapy for partial seizures with complex symptomatology (psychomotor, temporal lobe), generalized tonic-clonic seizures (gran mal)

Question 4

Indication for clonazepam

Answer 4

absence and myoclonic seizures, seizure clusters

Question 5

What class of drug is clonazepam?

Answer 5

benzodiazepine

only take at night

Question 6

Indication for ethosuximide

Answer 6

absence

Question 7

What is the DOC for petite mal/absence seizures?

Answer 7

ethosuximide

Question 8

Indication for felbamate

Answer 8

monotherapy and adjunctive therapy for partial-onset seizures and tonic-clonic seizures in people over the age of 14

Question 9

What drug can be used to treat atonic seizures associated with LGS in children aged 2 to 14?

Answer 9

felbamate

Question 10

AE of felbamate

Answer 10

aplastic anemia

liver failure

Question 11

_____________ is only used in pt w/very severe epilepsy d/t adverse effects (Liver failure, aplastic anemia)

Answer 11

felbamate

Question 12

_____________ is used as a add on therapy for partial seizures with or without secondary generalization in patients 12 years of age and older

Answer 12

gabapentin

Question 13

_______________ is intended more for partial seizures

Answer 13

gabapentin

Question 14

What are the AE of gabapentin?

Answer 14

unsteadiness
weight gain
fatigue
dizziness

Question 15

Gabapentin is recommended in use for those ages _____ and older

Answer 15

12

Question 16

Gabapenin is not effective for ___________ seizures

Answer 16

primary
absence
myoclonic
primary generalized tonic-clonic

Question 17

Gabapentin (_________)

Answer 17

neurontin

Question 18

Gabapentin can also be used for the treatment of _________________

Answer 18

fibromyalsia

works on gaba receptor, which is inhibitory

Question 19

dont need to know lacosamide…

Answer 19

nope

Question 20

______________ is a broad spectrum alternative to depakote

Answer 20

lamotrigine

Question 21

What is a benefit of lamictal vs. depakote?

Answer 21

less AE

Question 22

______________ is indicated for simple and complex seizures

Answer 22

lamictal

Question 23

_____________ is used to treat seizures associated with lennox-gastaut syndrome

Answer 23

Lamictal

Question 24

AE of Lamictal

Answer 24

dizziness
fatigue
insomnia
SJS –rare

Question 25

_______________ is an add on therapy for partial-onset seizures

Answer 25

levetiracetam

Question 26

Ages 4, use keppra to treat ____________

Answer 26

partial onset seizures

Question 27

Ages 12, use keppra for__________

Answer 27

juvenile myclonic epilepsy

Question 28

AE of keppra

Answer 28

irritability hostility depression (1/3 of pt) rash

Question 29

______________ is similar to carbamazepine except its not as effective against absence or myoclonic seizures

Answer 29

oxacarbazepine

Question 30

AE of oxacarbazepine

Answer 30

anaphylaxis angioedema hyponatremia SJS

Question 31

Oxacarbazepine must be taken at least ______ times a day

Answer 31

at least 2

Question 32

___________ is an add on therapy for partial and tonic clonic seizures

Answer 32

phenobarbital

Question 33

phenobarbital is a good therapy for _____________

Answer 33

status epilepticus

Question 34

How do you take phenobarbital?

Answer 34

at night, its a barbituate

Question 35

AE of phenobarbital

Answer 35

``` respiratory OD sedation SJS liver/blood disorder dependence fetal health ```

Question 36

Phenobarbital (_______)

Answer 36

luminal

Question 37

The indications for oxacarbazepine are the same as _________________

Answer 37

carbamazepine

Question 38

______________ is used as monotherapy for partial seizures and primary GTC

Answer 38

phenytoin

Question 39

Phenytoin is safe for what age group?

Answer 39

all

Question 40

______________ is best for partial onset seizures

Answer 40

phenytoin

Question 41

_____________ is generally not very effective against clonic, myoclonic and atonic seizures and in the lennox-gastaut syndrome

Answer 41

phenytoin

Question 42

Phenytoin is _________________ against lennox-gastaut syndrome

Answer 42

not effective

Question 43

Phenytoin _______________ be used for febrile seizures in infants

Answer 43

should not

Question 44

AE of phenytoin

Answer 44

unsteadiness and moderate cognitive problems, difficult to control levels, bone health, fetal heath, rash **potential cosmetic (body/face hair growth, skin issues)

Question 45

What is a unique AE of phenytoin?

Answer 45

Hair growth in random places | **gingival hyperplasia

Question 46

Phenytoin (____) is used for _______________

Answer 46

dilantin | maintenance

Question 47

______________ may control the tonic-clonic component of the lennox-gastaut syndrome

Answer 47

phenytoin | --but for the most part it has limited value in this syndrome

Question 48

_______________ is an add on therapy for partial and secondarily generalized seizures ONLY

Answer 48

pregabalin

Question 49

_____________ will NOT work in primary generalized seizures like absence, myoclonic or primary generalized tonic-clonic seizures

Answer 49

pregabalin

Question 50

What is a pro about pregabalin?

Answer 50

no drug interactions, no liver metabolism, no protein binding

Question 51

Pregabalin has similar AE as ___________

Answer 51

gabapentin | Weight gain, fatigue, dizziness-nothing seriously concerning

Question 52

Dont need to know primidone

Answer 52

nope

Question 53

Dont need to know rufinamide

Answer 53

nope

Question 54

_____________ can be used as monotherapy or as adjunctive therapy for partial onset seizure in children who are between the ages of 2-16

Answer 54

topiramate

Question 55

____________ is an FDA approved as initial monotherapy for pateints 10 years of age and older with partial onset or primary generalized tonic clonic seizures

Answer 55

topiramate

Question 56

Dosage for topiramate

Answer 56

start at 25 bid and increase by that amount weekly

Question 57

AE of topiramate

Answer 57

renal stones, glaucoma, weight loss, metabolic acidosis, behavioral issues-depression, agitation, hostility, psychosis, sulfa allergy**

Question 58

__________ are seen in about 1/3 of those taking topiramate

Answer 58

cognitive problems

Question 59

Topiramate is available in ______________

Answer 59

tablets and sprinkle capsules

Question 60

_______________ is used as monotherapy and adjuctive therapy for partial onset seizures in adults and children ages 2-16

Answer 60

topiramate

Question 61

____________ is used for patients of all ages as monotherapy or adjunctive therapy for simple or complex absence seizures

Answer 61

valproic acid (depakote)

Question 62

What kind of seizures can you treat with valproic acid?

Answer 62

simple or complex absence seizures | partial seizures

Question 63

AE of valproic acid

Answer 63

weight gain, tremor, hair loss, GI upset, blood disorders, hepatic or pancreatic injury, bone health (osteoporosis) fetal health

Question 64

What are the indications for vigabatrin?

Answer 64

partial seizures with or without secondary generalization, infantile spasms

Question 65

AE of vigabatrin

Answer 65

blindness/retinal toxicity

Question 66

What drug is associated with blindness/retinal toxicity?

Answer 66

vigabatrin

Question 67

dont need to know zonisamide

Answer 67

nope

Question 68

What are the indications for acetazolamide?

Answer 68

absence seizures, unlocalized seizures, catamenial seizures

Question 69

Acetazolamide is also used for the treatment of _____________

Answer 69

glaucoma

Question 70

What drug is also used to treat glaucoma?

Answer 70

acetazolamide

Question 71

AE of acetazolamide

Answer 71

tinnitus*, numbness*, tingling, nausea, vomiting, loss of appetite, rash (sulfa allergy), SJS, blood disorders acidosis