Second Half Flashcards

(27 cards)

1
Q

DNA

A

Deoxyribonucleic acid
- Governs the process of heredity

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2
Q

RNA

A

Ribonucleic acid
- involved in gene expression, and protein synthesis

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3
Q

Transforming principle

A

Dead pathogenic bacteria had passed on their disease, causing properties to live non-pathogenic bacteria

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4
Q

Hershey and Chase

A

DNA is the hereditary information

  • radioactive protein, and DNA were allowed to infect the bacteria, but only the DNA had entered the bacteria
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5
Q

Levene

A

Nucleic acids are made up of long chains of nucleotides
-each nucleotide is made up of carbon sugar, a phosphate, and one of the five nitrogen bases

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6
Q

Five nitrogen bases

A

Adenine, thymine, guanine, cytisine, uracil

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7
Q

Chargaffs rule

A

The amount of adenine is equal to the amount of thymine
The amount of cytosine is equal to the amount of guanine

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8
Q

Watson and Crick

A

Used x-ray crystallography to conclude the DNA has a helical structure, and the nitrogen bases are on the inside and the back bone is on the outside

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9
Q

Transcription

A

DNA unzips and RNA polymerase catalyze the reaction to bring mRNA nucleotides to the coding side of the DNA molecule, forming an mRNA strand

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10
Q

mRNA

A

Formed through protein synthesis, the mRNA strand creates the complementary nucleotides of the coding strand, and as in transported from the nucleus to the ribosome

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11
Q

Translation

A

Ribosomes read the mRNA in groups of three bases, called the codons

  • As a codon is red, a tRNA molecule with an amino acid attaches to the mRNA codon
  • As the next codon is read, the tRNA is inserted into place, the amino acids, next to each other and attach
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12
Q

Polypeptide

A

Long chain of amino acids
Begin with an initiator codon and finishes with a stop or terminator codon

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13
Q

tRNA

A

Transfer RNA
Contains the anticodon as well as the amino acid that will be used in protein synthesis

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14
Q

Codon

A

Group of three bases along the mRNA

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15
Q

Anti Codon

A

Group of three bases attached to the tRNA that is complementary to the codon on the mRNA

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16
Q

Semiconservative

A

Each molecule of DNA contains one strand of the new complementary DNA molecule and one original parent strand

17
Q

Replication origin

A

The start of DNA replication

18
Q

Helicase

A

Binds the DNA at the replication origin and unwinds the helix

19
Q

Replication bubble

A

The unwound region of DNA

20
Q

Replication fork

A

The Y shaped area of the DNA that is unwinding

21
Q

DNA polymerase

A

Add new nucleotides to the strand
- only works 5 to 3 direction

22
Q

Leading strand

A

The strand that is replicated continuously

24
Q

Legging strand

A

The strand that is replicated in short segments

25
Okazaki fragments
Short segments created in the lagging strand
26
Ligase
Spices the nucleotides back together to the backbone in the legging strand
27
How proofreading is done?
DNA polymerase proofreads the strand - No hydrogen bonds means a mismatch - size difference means mismatch