Section B - 12.5, 6 Flashcards
(29 cards)
Phases of cardiac cycle
Systole, diastole
Systole
Ventricular contraction and blood ejection
Diastole
Alternating period of ventricular relaxation and blood filling
First part of systole
Isovolumetric ventricular contraction - increasing ventricular blood pressure
Second part of systole
Ventricular ejection - pressure in ventricles > aorta and pulmonary trunk, blood is forced into aorta
First part of diastole
Isovolumetric ventricular relaxation - ventricles relax and the aortic and pulmonary valves close
Second part of diastole
Ventricular filling - blood flows in from atria
_% of ventricular filling occurs before atrial contraction
80%
End diastolic volume - EDV
Amount of blood in the ventricle at the end of ventricular diastole
End systolic volume - ESV
Amount of blood in the ventricle after ejection
Stroke volume =
EDV - ESV
Dicrotic notch
Combo of elastic recoil of the aorta and blood rebounding against the valse causing a rebound of aortic pressure
Lub
Closure of AV valves
Dup
Closure of pulmonary and aortic valves
Lub marks the onset of ___, dup occurs at the onset of ___
Systole, diastole
Laminar flow
blood flowing through valves and vessels in smooth concentric layers
Stenosis
Blood flowing rapidly in the usual direction through an abnormally narrowed valve
Insufficiency
Blood flowing between the two atria or two ventricles through a small hole in the wall separating them (septal defect)
Cardiac output
The volume of blood pumped per minute
CO =
HR x SV
Autonomous discharge rate of the SA node
100 bpm
Chronotropic effects
Activity in the parasympathetic neurons causing heart rate to decrease, activity in sympathetic neurons causing it to increase
___ stimulation increases the slope of the pacemaker potential by increasing ___ channel permeability
Sympathetic, F-type
Increased parasympathetic input ___ heart rate
decreases