Sedation Flashcards
(2 cards)
1
Q
Mechanism of midazolam
A
Increases activity of GABA (an inhibitory neurotransmitter) in the CNS resulting in hyper polarization of neuronal cells that take longer to depolarize
2
Q
Mechanism of ketamine
A
Non competitive NMDA receptor antagonist that blocks glutamate reducing polysynaptic spinal reflexes.
