sedatives Flashcards
(45 cards)
ramsay scale 1
anxious/agitated
ramsay 2
cooperative/oriented/tranquil
ramsay 3
responds only to verbal commands
ramsay 4
asleep with brisk response to stimulation
ramsay 5
asleep with sluggish response to stimulation
ramsay 6
asleep with no response to stimulation
level 1 sedation
anti anxiety; can respond to verbal commands
level 2 sedation
moderate sedation/analgesia; can respond to verbal commands
level 3 sedation
deep sedation/analgesia; can impair airway, responds to painful stimuli
level 4 sedation
general anesthesia; pt can’t be aroused
what do barbiturates have
sedatives, hyponitcs, some amnesia
what is the sedative of choice in head trauma/icp/ status epilepticus
barbiturates
what side effects do barbiturates have
not good for pts with lung disease, causes broncho/laryngospasm; not good for asthmatics, causes hypovolemia/tension and so use 1/2 dose
methohexital
anesthetic, hypnotic, sedative; causes loss of spent ventilations, quick onset/duration, histamine release
pentothal
sedative/hyponotic, short acting/rapid onset, decreases cerebral metabolic rate and ICP, negative inotrop
propofol
non barbiturate; deep sedation with less airway reactivity, decreases cerebral metabolic rate and ICP; not excreted by kidneys or liver; can cause metabolic acidosis; good for antiseizure
etomidate
not barbiturate; good for intubations, not good for seizure patients, short duration, not continuous infusion
benzodiazepines
sedative/hypnotic/anxiolysis agents; anticonvulsant with amnesia affects, causes decreased ventilations, no analgesic
diazepam
benzo; rapid onset/duration 2-4 hours
lorazepam (ativan)
benzo; longer term sedation, peaks in 20-30 min
midozolam (versed)
benzo; good procedural drug, short acting, anxiolysis; duration 60-90 min
what is the benzo reversal agent
flumuzenil or romazican
chloral hydrate
sedative/hypnotic, used in children for long procedures, no analgesic, can cause respiratory depression if combined with other sedative
meperidine-demeral
analgesic - narcotic - duration 2-3 hours (in b/w fentanyl/morphine) causes increased HR, and seizures, watch in pts with renal failure