selection and evolution Flashcards
(83 cards)
define phenotypic variation
is the difference in phenotypes between organisms of the same species
In some cases, phenotypic variation is explained by what?
explained by genetic factors:
For example, the four different blood groups observed in human populations are due to different individuals within the population having two of three possible alleles for the single ABO gene
explained by environmental factors:
For example, clones of plants with exactly the same genetic information (DNA) will grow to different heights when grown in different environmental conditions
can also be explained by a combination of genetic and environmental factors:
For example, the recessive allele that causes sickle cell anaemia has a high frequency in populations where malaria is prevalent due to heterozygous individuals being resistant to malaria
What can the complete phenotype of an organism be determined by?
the expression of its genotype and the interaction of the environment on this:
Phenotype = Genotype + Environment
define genetic variation
The small differences in DNA base sequences between individual organisms within a species population
Organisms of the same species will have very similar genotypes, but two individuals (even twins) will have differences between their DNA base sequences
Considering the size of genomes, these differences are small between individuals of the same species
Genetic variation is transferred from….
one generation to the next and it generates phenotypic variation within a species population
Genetic variation is caused by the following processes as they result in a new combination of alleles in a gamete or individual:
-Independent assortment of homologous chromosomes during metaphase I
- crossing over of non-sister chromatids during prophase I
-Random fusion of gametes during fertilization
what do mutations result in?
generation of new alleles
The new allele may be advantageous, disadvantageous or have no apparent effect on phenotype (due to the fact that the genetic code is degenerate
New alleles are not always seen in the individual that they first occur in
They can remain hidden (not expressed) within a population for several generations before they contribute to phenotypic variation
Genes can have varying effects on an organism’s phenotype. what are the effects?
The phenotype may be affected by a single gene or by several
The effect that the gene has on the phenotype may be large, small and/or additive
Genes can have varying effects on an organism’s phenotype. what are the effects?
The phenotype may be affected by a single gene or by several
The effect that the gene has on the phenotype may be large, small and/or additive
what can also have an impact on its phenotype?
the environment that an organism lives in.
Different environments around the globe experience very different conditions in terms of the:
Length of sunlight hours (which may be seasonal)
Supply of nutrients (food)
Availability of water
Temperature range
Oxygen levels
Changes in the factors above can affect how organisms grow and develop
For example, plants with a tall genotype growing in an environment that is depleted in minerals, sunlight and water will not be able to grow to their full potential size determined by genetics
Variation in phenotype caused solely by environmental pressures or factors…
cannot be inhrited by an organisms offspring
- only alterations to the genetic componnt of gametes will ever be inhertied.
define variation
refers to the differences that exist between at least two things (be it a level, amount, quantity or feature of something)
define variation in relation to natural selection
refers to the differences that exist between individuals of a species
This may also be referred to as intraspecific variation
intraspecific- something that occurs/exists within a species
Variation observed in the phenotypes of organisms can be due to..
Qualitative or quantitative differences.
Features of Discontinuous variation
- distinct classes/categories exist
- characterisitcis cannot be measured over a wide range
- individiuals cannot have features that fall between categories
- (different size bars on bar graph)
see graphs on save my exams
Qualitative differences in the phenotypes of individuals within a population give rise to discontinuous variation
Qualitative differences fall into discrete and distinguishable categories, usually with no intermediates (a feature can’t fall in between categories)
For example, there are four possible ABO blood groups in humans; a person can only have one of them
It is easy to identify discontinuous variation when it is present in a table or graph due to the distinct categories that exist when data is plotted for particular characteristics
Features of continuous variation
- no distinct classes/categories exist
- characteristics can be measured and fall within a range between 2 extremes
- (bell shaped curve graph)
occurs when there are quantitative differences in the phenotypes of individuals within a population for particular characteristics
Quantitative differences do not fall into discrete categories like in discontinuous variation
Instead for these features, a range of values exist between two extremes within which the phenotype will fall
For example, the mass or height of a human is an example of continuous variation
The lack of categories and the presence of a range of values can be used to identify continuous variation when it is presented in a table or graph
Define discontinuous variation
refers to the differences between individuals of a species where the differences are qualitative (categoric)
define continuous variation
is the differences between individuals of a species where the differences are quantitative (measurable)
Each type of variation can be explained by genetic and / or environmental factors
Genetic basis of discontinuous variation
This type of variation occurs solely due to genetic factors
The environment has no direct effect
Phenotype = genotype
At the genetic level:
Different genes have different effects on the phenotype
Different alleles at a single gene locus have a large effect on the phenotype
Remember diploid organisms will inherit two alleles of each gene, these alleles can be the same or different
A good example of this is the F8 gene that codes for the blood-clotting protein Factor VIII
The different alleles at the F8 gene locus dictate whether or not normal Factor VIII is produced and whether the individual has the condition haemophilia
Genetic basis of continuous variation
This type of variation is caused by an interaction between genetics and the environment
Phenotype = genotype + environment
At the genetic level:
Different alleles at a single locus have a small effect on the phenotype
Different genes can have the same effect on the phenotype and these add together to have an additive effect
If a large number of genes have a combined effect on the phenotype they are known as polygenes
Genetic basis of continuous variation
This type of variation is caused by an interaction between genetics and the environment
Phenotype = genotype + environment
At the genetic level:
Different alleles at a single locus have a small effect on the phenotype
Different genes can have the same effect on the phenotype and these add together to have an additive effect
If a large number of genes have a combined effect on the phenotype they are known as polygenes
The additive effect of genes
The height of a plant is controlled by two unlinked genes H / h and T / t
The two genes have an additive effect
The recessive alleles h and t contribute x cm to the plants height
The dominant alleles H and T contribute 2x cm to the plants height
The following genotypes will have the following phenotypes:
h h t t : x + x + x + x = 4x cm
H H T T : 2x + 2x + 2x + 2x = 8x cm
H h T t : 2x + x + 2x + x = 6x cm
H H T t : 2x + 2x + 2x + x = 7x cm
H h T T : 2x + x + 2x + 2x = 7x cm
h h T t : x + x + 2x + x = 5x cm
H h t t : 2x + x + x + x = 5x cm
Be careful when answering questions that involve polygenes or genes with an additive effect. It is not a given that each gene will have the same effect on the phenotype as in the example above so make sure to double check the information you have been given in the question.
statistical test
t-test what is it used to comapare?
can be used to compare the means of two sets of data and determine whether they are significantly different or not
The formula for the t-test will be provided in the exam, but formulae for how to calculate the number of degrees of freedom is not provided in the exam and must be learnt
The sets of data must follow a rough normal distribution, be continuous and the standard deviations should be approximately equal
The standard deviation (s) must be calculated for each data set before the t-test can be carried out
A null hypothesis should also be given
This is a statement of what we would expect if there is no significant difference between two means, and that any differences seen are due to chance
T-test
If there** is a statistically significant difference **between the means of two sets of data what do you conclude?
If there is a statistically significant difference between the means of two sets of data, then the observation is not down to chance and the null hypothesis can be rejected
look at save my exams for t-test formula and how to calculate