Self Administered Meds INFO

Question 1

Afinitor

everolimus

Answer 1

Indication: post-menopausaul women with advanced hormone receptor positive, HER2- Negative Breast cancer (failure of treatment with letrozole or anastrozole), progressive tumor, Renal cell carcinoma
Dosing: avg 10mg daily (2.5mg/ 5mg/7.5mg/10mg)
Storage: tablets
Common SE: diarrhea, constipation, nausea, change of taste, weight loss, fever, nosebleeds

Question 2

Cabometyx

cabozantinib

Answer 2

Indication: advanced kidney cancer (renal cell carcinorma) liver cancer previously treated with sorafenib, advanced renal carcinoma
Dosing: no food, one hour before or 2 after eating (60mg, 40mg, 20mg daily)
Storage: tablets
Common SE: bleeding (hemorrhage), stomach tear, blood clots, stroke, hypertension, diarrhea, severe jaw bone, would healing problems

Question 3

exemestane

Brand: Aromasin

Answer 3

Indication: advanced breast cancer in women post menopause
Dosing: avg 25 mg daily
Storage: tablet
Common SE: Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhea, dizziness

Question 4

Gilotrif

afatinib

Answer 4

Indication: non small cell lung cancer, previously treated for metastatic lung cancer
Dosing: (40mg, 30mg, 20mg) once daily, 1 hr or 2 hr before/after eating
Storage: tablets
Common SE: diarrhea, skin reactions (sunlight sensitivity) lung or breathing problems, liver problems, tear in your stomach , eye problems, heart problems, rash acne, may decrease fertility in men and women

Question 5

Gleevec

imatinib

Answer 5

Indication: leukemia, KIT, or GIST (gastrointestinal stromal tumor)
Dosing: (100mg, 400mg)
Storage: tablets
Common SE: EDEMA sever fluid retention, increased pressure in heart and brain, heart failure, liver problem, hemorrhage, skin blistering, thyroid hormone level lowered

Question 6

Ibrance

palbociclib

Answer 6

Indication: HR positive, HER2-negative advanced or metastatic breast cancer in postmenopausal women
Dosing: capsules/ tablets 125mg, 100mg, 75mg (highest dose weaned off after 21 days)
Storage:
Common SE: leukopenia, infections, fatigue, nausea, stomatitis, anemia, alopecia, diarrhea, thrombocytopenia, rash, vomiting decreased appetite

Question 7

Imbruvica

ibrutinib

Answer 7

Indication: chronic lymphocytic leukemia, small lymphocytic lymphoma,
Dosing: #1 420mg tab daily, #3 140mg capsules
Storage:
Common SE: low platelet count, diarrhea, neutropenia, anemia, fatigue, musculoskeletal pain, muscle spasms, joint pain

Question 8

jakafi

Brand: Ruxolitinib

Answer 8

Indication: (Chemotherapy) myelofibrosis and polycythemia vera, acute graft versus host disease
Dosing: 5mg or 10mg twice daily
Storage: tablet
Common SE: low platelet or red blood cell counts, bruising, dizziness, headache and diarhea, fluid retention, skin cancers, increase cholesterol

Question 9

Kisqali

ribociclib

Answer 9

Indication: combination with aromatase inhibitor for perimenopausal or postmenopausal women with HR positive, HER2 negative advanced breast cancer
Dosing: #3 200mg tablets daily with or without food for 21 days
Storage:
Common SE: inflammation of lungs, severe skin reaction, heart rhythm, neutropenia, nausea, fatigue, diarrhea, vomiting, constipation cough, fertility problems

Question 10

Zytiga

abiraterone acetate

Answer 10

Indication: metastatic prostate cancer (combo with prednisone)
Dosing: 1000mg daily (+5mg prednisone)
Storage:
Common SE: fatigue, arthralgia, hypertension, nausea, edema, hyperkalemia, upper respiratory infection

Question 11

Alecensa

alectinib

Answer 11

Indication: non small cell lung cancer that has spread and caused by abnormal anaplastic lymphoma kinase
Dosing: 150mg capsules (600mg orally twice daily with food)
Storage:
Common SE: hepatotoxicity, lung problems, kidney problems, bradycardia, muscle pain or myalgia, constipation, fatigue

Question 12

Nexavar

sorafenib

Answer 12

Indication: kidney liver (hepatocellular carcinoma) and thyroid cancer
Dosing: 400mg twice daily 1hr before, 2 hours after meals
Storage:
Common SE: diarrhea, fatigue, infection, alopecia, hemorrhage, hypertension, heart problems

Question 13

Lonsurf

trifluridine and tipiracil

Answer 13

Indication: colorectal cancer that has spread, gastric cancer
Dosing: 35mg total::: 15mg trifluridine 6.14 mg tipiracil or 20mg trifluridine and 8.19mg tipiracil
Storage:
Common SE: low blood count, anemia, neutropenia, fatigue, thrombocytopenia, decreased appetite, diarrhea, vomiting

Question 14

Sprycel

dasatinib

Answer 14

Indication: Chronic Myeloid leukemia and patients did not tolerate Gleevec
Dosing: 20mg, 50mg, 70mg, 80mg, 100mg, 140mg tablets
Storage:
Common SE: myelosuppression enema, neutropenia, pyrexia, muscle pain

Question 15

Revlimid

lenalidomide

Answer 15

Indication: myelodysplastic syndrome, multiple myeloma, and mantle cell lymphoma
Dosing: capsules 2.5, 5, 10, 15, 20, 25mg (25 mg daily for 28 day cycle) combo w dexamethasone
Storage:
Common SE: diarrhea, fatigue, anemia, constipation, neutropenia, leukopenia

Question 16

Tarceva

erlotinib

Answer 16

Indication: non-small lung cancer who has spread throughout the body, epidermal growth factor receptor mutation (chemotherapy)
Dosing: 25mg, 100mg, 150mg
Storage:
Common SE: rash, diarrhea, anorexia, fatigue, dyspnea, cough, nausea, vomiting

Question 17

Promacta

eltrombopag

Answer 17

Indication: ITP chronic thrombocytopenia, used to raise platelet counts
Dosing: Tablets 12.5mg, 25mg, 50mg, 75mg or oral suspension 12.5mg and 25mg
Storage:
Common SE: urinary tract infection, pain or swelling of throat or mouth, abnormal liver functions, muscle aches

Question 18

Stivarga

regorafenib

Answer 18

Indication: metastatic colorectal cancer, GIST, hepatocellular carcinoma
Dosing: 40mg 4 tablets once daily 160MG total
Storage:
Common SE: gastrointestinal and abdominal pain, hypertension, infection, dysphonia, fever, hepatoxicity

Question 19

Tykerb

lapatinib

Answer 19

Indication: metastatic breast cancer, HER2+
Dosing: 250mg tablets (5 tablets daily average)
Storage:
Common SE: liver damage, diarrhea, nausea, fatigue

Question 20

Pomalyst

pomalidomide

Answer 20

Indication: myeloma, AIDS related Kaposi sarcoma
Dosing: addition to dexamethasone, capsules 1,2,3,4mg …. 4mg daily for 21 days
Common SE: fatigue, asthenia, neutropenia, anemia, constipation, nausea, diarrhea, dyspnea, upper respiratory infection

Question 21

Lynparza

olaparib

Answer 21

Indication: advanced ovarian cancer, fallopian tube cancer, primary peritoneal cancer (with abnormal BRCA gene) / metastatic breast cancer
Dosing: 150mg tablet
Common SE: bone marrow issues MYELODYSPLASTIC SYNDROME, weakness, weight loss, shortness of breath, blood in urine or stool

Question 22

Venclexta

veneotclax

Answer 22

Indication: chronic lymphocytic leukemia or small lymphocytic lymphoma
Dosing: 10, 50, 100mg, one tablet once daily
Common SE: neutropenia, thrombocytopenia, anemia, diarrhea, nausea, upper respiratory infection

Question 23

Gleostine

lomustine

Answer 23

Indication: Hodgkin lymphoma disease, brain tumors
Dosing: capsules 100, 40, 10mg .. average of 160mg dose every 6 weeks
Storage: room temperature
Common SE: nausea, severe vomiting, diarrhea, appetite loss, mouth sores, alopecia, myelosuppression, neurotoxicity

Question 24

Verzenio

abemaciclib

Answer 24

Indication: advanced or metastatic breast cancers
Dosing: 50,100,150,200mg … 150 mg combo or 200 as single agent
Common SE: diarrhea, neutropenia, leukopenia, nausea, abdominal pain, infections, fatigue anemia

Question 25

Mekinist | tramtinib

Answer 25

Indication: Advanced BRAF+ Melanoma and BRAF Mutation positive metastatic non small cell lung cancer Dosing: 0.5mg, 2mg tablets combo with dabrafenib capsules Common SE: bleeding, stomach tears , blood clots, heart problem, fever, breathing problems, skin reaction

Question 26

Ninlaro | ixazomib

Answer 26

Indication: multiple myeloma (bone marrow) Dosing: capsules 2.3,3.0,4.0mg administered daily once a week (combo w dexamethasone) Common SE: constipation, diarrhea, macular eruption, maculopapular rash, nausea, neuropathy, skin rash, hepatic insufficiency

Question 27

Tafinlar | dabrafenib

Answer 27

Indication: BRAF+ advanced melanoma, metastatic non small cell lung cancer Dosing: 50, 75mg capsules 150mg daily in combo w Mekinist Common SE: hyperkeratosis, headache, pyrexia, arthralgia, papilloma, alopecia

Question 28

Lenvima | lenvatinib

Answer 28

Indication: inoperable liver cancer, differentiated thyroid cancer, advanced kidney cancer Dosing: 4,10mg capsules Common SE: hypertension, fatigue, diarrhea, arthralgia, myalgia, decreased appetite, decreased weight, nausea

Question 29

Sutent | sunitinib malate

Answer 29

Indication: kidney cancer, GIST, pancreatic neuroendocrine tumor Dosing: capsules 12.5mg, 25mg, 37.5mg 50mg capsules Common SE: indigestion, decreased appetite, feeling weak, mouth sores, blisters, rash, bruising, increased blood pressure

Question 30

Tagrisso | osimertinib

Answer 30

Indication: non-small cell lung cancer whos tumor continues to grow Dosing: 80mg and 40mg Common SE: lung problems, heart problems and heart failure, eye problems, skin,

Question 31

Temodar | temozolomide

Answer 31

Indication: glioblastoma, brain tumor Dosing: 150mg daily for 5 days Common SE: nausea, vomiting, loss of appetite, mouth sores, changes in taste, constipation, tiredness,

Question 32

Tasigna | nilotinib

Answer 32

Indication: leukemia, acute lymphoblastic leukemia Dosing: capsules 150mg, starting dose of 300mg twice daily Common SE: diarrhea, nausea, muscle spasms, vomiting, rash, headache, pruritus, alopecia, dry skin, fatigue

Question 33

Votrient | pazopanib

Answer 33

Indication: advanced renal cell carcinoma and soft tissue carcinoma Dosing: 200m tablets, 800mg daily dosing Common SE: hepatoxicity

Question 34

Xeloda | capecitabine

Answer 34

Indication: breast cancer and colorectal cancer, colon cancer, stomach cancer Dosing: 150mg and 500mg Common SE: severe renal impairment, hypersensitivity, and foot syndrome, abdominal pain, fatigue

Question 35

Xtandi | enzalutamide

Answer 35

Indication: prostate cancer Dosing: 40,80mg tablets or 40mg capsules Common SE: seizures, hypersensitivity, encephalopathy syndrome, heart disease, hypertension