Senses Flashcards

0
Q

How is the eye able to move?

A

It contains extraocular muscles

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1
Q

How does light energy pass to the optic nerve?

A

Via the cornea, past the lens and toward the fovea

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2
Q

What is the job of photoreceptors?

A

Converge light energy and neural activity

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3
Q

What types of photoreceptors are there?

A

Rod and cone cells

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4
Q

What do rod cells detect?

A

They are achromatic, so detect changes to light intensity

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5
Q

What do cones cells detect?

A

The are trichromatic, so allow colour vision

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6
Q

What function do bipolar cells have?

A

They create a direct pathways from photoreceptors to ganglion cells

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7
Q

What do retinal ganglion cells do?

A

They leave the eye and form the optic nerve

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8
Q

How is retinal change caused by rhodopsin or iodopsin?

A

They absorb the photon in the disc membrane, changing the retinal schiff base cofactor, leading to retinal change

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9
Q

What does retinal change cause?

A

A series of intermediates leading to a G protein activating transducin

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10
Q

What effect does transducin have in the eye?

A

Activates cGMP phosphodiesterase, converting cGMP to 5’cGMP

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11
Q

Photoreceptor Na+ channels close due to what change?

A

A net decrease in cGMP concentration

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12
Q

Outer segments of the photoreceptors become hyper polarised due to what change?

A

The decreased Na+ inside the cell

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13
Q

Outer photoreceptors hyper polarisation causes what?

A

Ca2+ VGIC to close, so intracellular Ca2+ concentrations fall

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14
Q

Low levels of intracellular Ca2+ levels in photoreceptors causes what?

A

Less glutamate to be released by exocytosis to bipolar cells

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15
Q

When rod and come cells are stimulated by light, what happens?

A

They produce less NT, which can stimulate or inhibit bipolar cells

16
Q

What is included in the retinofusal projection?

A

The optic nerve, optic chiasm and optic tract

17
Q

What is the visual field?

A

The entire region of space seen by both eyes looking straight ahead

18
Q

What do optic nerve fibres do in the optic chiasm?

A

Cross over to the opposite side

19
Q

What does a 2x2mm cortex contain?

A

2 ocular dominance columns, 16 blobs and 2 complete orientation columns

20
Q

What path does a sound wave take in the ear?

A

Down the auditory meatus, to the tympanic membrane where it enters the cochlea

21
Q

What happens to the pressure waves in the cochlea?

A

They’re turned into nerve signals

22
Q

The cochlea is made up of what 3 vesicles?

A

Scala media, scala vestibuli and scala tympani

23
Q

What are the sensory receptors in the ear?

A

The hair cells that lie in the scala media

24
How does vibration cause transmission?
Causes the organ of corti to move, the tectorial membrane distorts, so the sterocilia are disturbed producing mechanoelectrical transduction
25
Endolymph of the scala media contains high concentrations of what ion?
K+
26
Stereocilia disturbance causes depolarisation which results in...?
VGIC for Ca2+ to open and the NT to be released
27
Where in the brain is the auditory complex located?
On the superior temporal gyrus in the temporal lobe of the brain
28
What are the 3 senses associated with the nose and mouth?
Olfactory, gustatory and trigeminal
29
How do odourants enter the nasal cavity?
They dissolve in mucus, and bind to cilia that project into the nasal cavity
30
How do the cilia then produce signals?
Their axons project into the olfactory bulb, and signals are sent to the pyriform cortex in the temporal lobe
31
There is a less direct route of olfactory signalling, what does this involve?
The odourants bind to cilia, activate G proteins, produce cAMP, opening Ca2+ and Na+ channels, which leads to Cl- channels opening resulting in depolarisation
32
What are taste sensitive structure called?
Papillae
33
Explain the circumuallate papillae.
Largest with thousands of taste buds, located posteriorly
34
What characterises foliage papillae?
Elongated structures with hundreds of taste buds, lying along the posterior lateral edge
35
What are the taste sensitive structures at the tip of he tongue?
The fungiform papillae, which are the smallest with only a few taste buds
36
From back to front of the tongue, name the taste sensations.
Bitter, sour, salty, sweet
37
How is the taste transduction achieved?
Dissolved molecules interact with receptors, depolarisation, and action potential, increased intracellular Ca2+ and release of NT, exciting nerve fibres