Sensory Systems Flashcards

(28 cards)

1
Q

What is the common purpose of sensory systems?

A

Provide information about external or internal environment, for generation of adaptive behavior

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2
Q

What is transduction?

A

Convert physical signal (energy) into neural signal

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3
Q

What is encoding?

A

Represent qualitative and quantitatie aspects of stimulus

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4
Q

What is perception?

A

Conscious awareness of stimulation

Doesn’t have to happen, e.g. blood pressure

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5
Q

What is the modality of a stimulus?

A

Quality or type of energy which is transduced

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6
Q

What are the five basic modalities of sensation?

A

Somatosensation

Vision

Audition

Olfaction

Gustation

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7
Q

What is an adequate stimulus?

A

Type of energy that activates a specific receptor at lowest energy level

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8
Q

What is intensity?

A

The strength of a stimulus

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9
Q

What is sensory threshold?

A

The lowest intensity which can be detected reliably (50% of the time)

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10
Q

What is the relationship between threshold and sensitivity?

A

Threshold is inversely related to sensitivity

Threshold is not fixed

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11
Q

Which direction does a decrease in sensitivity shift an intensity-response curve? Increase?

A

Decrease - shifts curve to the right (raises threshold)

Increase - shifts curve to the left (lowers threshold)

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12
Q

What is duration?

A

Length of stimulation

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13
Q

What is characteristic of slowly adapting receptors?

A

Will continue to fire as long as stimulus is present at fixed level

Provides information about stimulus duration

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14
Q

What is characteristic of rapidly adapting receptors?

A

Will fire in response to a change in stimulus intensity

Provides information about the dynamic aspects of a stimulus

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15
Q

What is a receptive field?

A

Specific spatial location where stimulus energy is effective in stimulating a receptor

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16
Q

What is the mechanism of a mechanoreceptor?

A

Tranduces physical energy (membrane deformation) into neural activity

Linked to membrane or cytoskeleton in some way

Cation channel permeable to Na and K that depolarizes the receptor cell

17
Q

What are thermal receptors?

A

Transient Receptor Potential (TRP channels) channels that are thermally stimulated (can be stimulated by other means)

Cation channels that vary in ion permeability depending on channel type

18
Q

What is the difference between cold and warm receptors?

A

Cold: TRP channels that are activated at low temps (12-35)

Warm: TRP channels activated by high temperatures

19
Q

What is another type of stimulus for thermally activated TRP channels?

A

Chemical

Cold: menthol (mint)

Warm: capsaicin

20
Q

What are thermal nociceptors?

A

Pain receptors that are activated by extremes of heat or cold (<12C or >47C)

21
Q

What is receptor potential?

A

Sensory transduction causes channel opening and creates a graded potential

Fewer channels open: small receptor potential

More channels open: bigger receptor potential

22
Q

What must happen to trigger an action potential?

A

The capacitive current created by the receptor potential must depolarize the initial segment of the axon to threshold

23
Q

How is the intensity of a stimulus coded?

A

Frequency coding

Low intensity causes low fire rate

High intensity causes high firing rate

24
Q

How is the duration of a stimulation coded?

A

Encoded by the length of an action potential train (duration of transmitter release onto the second order neuron)

25
What is adaptation?
Reduced output despite sustained stimulation Caused by altered sensory transduction or change in membrane ion conductance
26
What are two ion conductance adaptation mechanisms?
Inactivation of inward currents (Na or Ca channels) Activation of outward currents (Ca activated K channel)
27
What is a calcium-activated potassium channel?
Needed for slow adaptation Increase in cytoplasmic Ca (due to HVA Ca channels) causes the channel to open Additional K conductance causes the membrane potential to "sag" back towards resting level, reduced rate of action potential firing
28
What are the functional zones of sensory receptors?
Transduction - sensory channels Integration (trigger) - cation channels, Ca-activated K channels Conduction - axon Transmission - axon terminal