Sepsis

Question 1

The primary tissue or organ that is targeted in sepsis is

Answer 1

endothelium (Cells that line the blood vessels).

Question 2

Sepsis is defined as life-threatening organ dysfunction caused by a _ response to infection.

Answer 2

dysregulated host

Question 3

The increased respiratory rate in sepsis is due to

Answer 3

increased hydrogen ion concentration

Question 4

Hypotension in hyperdynamic sepsis is due to …

Answer 4

a. loss of intravascular volume and impaired cardiac contractility
b. impaired vascular tone and loss of intravascular volume

Question 5

Source control in cases of suspected bacterial sepsis always includes all of the following except…

Answer 5

surgery

Question 6

RED ZONE CRITERIA: BP, LACTATE, BASE

Answer 6

SBP <90 MMHG
LACTATE >4MM/OL
BASE EXCESS <5.0

Question 7

YELLOW ZONE; RR, SP02, SBP, HR, LOC, TEMP

Answer 7

<10 >25 RR
Sp02 <95%
SBP <100 mmhg
HR <50 > 120
LOC
Temp <35.5 or >38.5
Lactate >2 mm/ol

Question 8

Fluid resus ; ED and Ward protocol

Answer 8

Emergency Department Give initial 20mL/kg bolus STAT, if no response repeat 20mL/kg STAT

Inpatient Initial 250-500mL bolus STAT, if no response repeat 250-500mL STAT

Question 9

Fluid resus aim

Answer 9

Use crystalloid e.g saline

Systolic above >100 mmHg

Question 10

Sepsis 6

Answer 10

1. Hudson’s mask
2. Blood cultures
3. Blood e.g. lactate
4. antibiotics
5. fluids resus
6. monitor

Question 11

Priorities after blood e.g. lactate

Answer 11

Antibiotics and Fluid resus

Question 12

antibiotic for neutropenic

Answer 12

> 30 minutes

Question 13

septic shock or meningococcal

Answer 13

> 1 hour

Question 14

other spesis

Answer 14

> 2 hours