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Sepsis Flashcards

(17 cards)

1
Q

Clinical syndrome defined as life threatening organ dysfunction due to dysregulated host response to infection.

A

Sepsis

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2
Q

How is SIRs characterised?

A

Temperature
Heart rate
Respiratory rate and
WBC count

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3
Q

How is septic shock characterised?

A

Sepsis with circulatory and cellular metabolism dysfunction.
Hypotension that requires vasopressor support.

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4
Q

What are the Clinical signs of sepsis?

A

Can range widely.
Lethargy, innapetance, V+…. Up to organ failure and decompensatory shock.

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5
Q

What is the Sepsis criteria in cats?

A

HRT < 140 > 225
RR > 40
Increased WBC count

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6
Q

What is the sepsis criteria for dogs?

A

HRT > 120
RR > 20
High WBC count

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7
Q

What are the common types of organ function associated with Sepsis?

A

AKI
GI signs in Dogs
ALI
ARDs

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8
Q

How many organs are affected in MOD?

A

2 or more.

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9
Q

What is damaged in sepsis that exacerbates coagulation activation and dysregulation?

A

Damage to the glycocalyx and the endothelium.

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10
Q

What clinicopathological abnormalities may be seen with sepsis?

A

Hyperlactataemia
Neutophillic leukocytosis
Dysregulation of coagulation
Hyper/Hypoalbuminrmia
Hypotension
Compromises endothelial function

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11
Q

Four common clinocopathological changes in routine lab work with sepsis include?

A

Hypo/hyperglycaemia.
Hypoalbuminaemia.
Hyoerbilirubinemia.
Ionised hypocalcaemia.

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12
Q

What values compared to peripheral blood is highly suggestive of septic peritonitis?

A

Lactate > 2 mmol/l
Glucose < 20 mg/dL

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13
Q

What drug is usually used as a first line vasopressor for septic patients?

A

Norepinephrine.

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14
Q

What drug/s are indicated if cardiac contractility is reduced?

A

Dobutamine CRI
Digoxin
Pumbobemdan

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15
Q

Why is Etomidate controversial in sepsis cases?

A

Effect on adrenal function and increased patient morbidity and mortality.

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16
Q

Ketamine supports the cardiopulmonary systems. In sepsis, what condition may it help prevent?