Sepsis And Postoperative Fever

Question 1

Which of the following is NOT correct regarding systemic inflammatory response syndrome (SIRS)?

• Temp <36 or >38.
• HR > 70.
• RR > 20 or PACO2 < 32.
• Leukocytes > 12,000 or < 4000

Answer 1

HR > 70

* should be > 90

Question 2

QSOFA is positive if two of the following is present

Answer 2

GCS < 15.
Systolic BP < 100.
RR > 22.

Question 3

SIRS + Infection =

Answer 3

Sepsis

Question 4

Sepsis + end organ damage =

Answer 4

Severe sepsis

Question 5

Severe sepsis + hypotension =

Answer 5

Septic shock

Question 6

Infection with inflammation of the dermis and subcutaneous layers of skin

Answer 6

Cellulitis

Question 7

Tx of abscess is

Answer 7

Drainage

Question 8

NECROTISING FASCIITIS RESULTS FROM A

Answer 8

Polymicrobial (group A Streptococci)

Question 9

Tx of necrotizing infections

Answer 9

Immediate surgical debridement + Antibiotics

Question 10

The most common organism causing gas gangrene?

Answer 10

Clostridium perfringens

Question 11

DESTROYS RED AND WHITE BLOOD CELLS, PLATELETS, FIBROBLASTS AND MUSCLE CELLS.

Answer 11

Alpha toxin such as lecithinase

Question 12

PRODUCES MYOCARDIAL SUPPRESSION

Answer 12

Phi toxin

Question 13

RESPONSIBLE FOR THE DESTRUCTION OF CONNECTIVE TISSUE AND BLOOD VESSELS.

Answer 13

Kappa toxin

Question 14

IP of c. Perfringens

Answer 14

< 24 h but it can range from 1h to 6 weeks

Question 15

Which of the following is NOT a component of the gas produced in gas gangrene?

• N.
• CO2.
• hydrogen sulphide.
• O2.

Answer 15

O2

Question 16

Management of gas gangrene

Answer 16

High dose penicillin + 3rd generation cephalosporins

Question 17

Prophylactic Antibiotics are indicated in wounds class

Answer 17

2 + 3

Question 18

If there is suspicion of pneumonia, bacteremia, sepsis or UTIs

Answer 18

Start broad spectrum antibiotics

Question 19

Antibiotics are NOT indicated for wound infection unless

Answer 19

Associated with cellulitis