Septation of the heart and Congenital Defects Flashcards
(26 cards)
What does the sinus venosus become?
-sinus venarum and coronary sinus
What does the primitive atrium become?
R + L atrium
What does the primitive ventricle become?
most of the definitive left ventricle
Bulbus Cordis becomes
right ventricle and outflow tract
Truncus Arteriosus become
ascending aorta and pulmonary artery [conotruncal septum]
The right side of the primitive atrium becomes?
right atriums pectinate
What is the crista terminalis?
-carry SA to AV node impulses
What is SEPTA and VALVES?
s: divides R/L chambers
V: flow of blood
How does the formation of septation occur?
-endocardial cushions (thickens up in the middle)
-Interatrial septum ( grows down)
-interventricular septum( grow up)
What occurs on Day 28 ?
-septum primum and endocardial cushions appear
what occurs in fetus heart on day 56?
-2nd septum and rapid growth of endo cardial tissues
Foremen secundum is:
Before the foramen primum closes - the septum primum develops small perforations to form a new foramen
Atrial Spetal Defect and the result:
-septum secundum is too short to cover foramen secundum
-results: right atrial and right ventricular hypertrophy may develop b/c PRESSURE is higher on LEFT atrium
Atrial septal defect: (betsy terms)
O2 blood should go to ventricle but its going to the right side so RIGHT side enlarge
Ventricular Septation:
occurs on 7th week and is NOT part of fetal circulation
-once closed, always closed
-grows cranially to allow blood to Ventr and bulbis cordis
Ventricular Septation (DEFECT)
-superior part of the the interventricular foramen fails to form thus causes the mixing of blood btw the ventricles.
-left side has high pressure bc its stronger
Truncus Arteriosus Septations from tissue from lateral wall flows out from:
truncus arteriosus and bulbus cordis
The fusion and making of the septum called
-conotruncal septum which spiral at 180
-divides the aorta and pulmonary trunck in 2 differnt outflow tracts
Tetralogy of Fallot (primary defect)
-UNEQUAL DIVISION of the outflow
Tetralogy Fallot results in 4 consequences:
- pulmonary stenosis
- ventricular septal defect
-displacement of aorta
-right ventricular hypertrophy
(exhibit cyanotic skin while crying)
Transposition of the Greater Arteries (TGA)
-conotruncal septa develop but does NOT SPIRAL into correct position
-left ventricle empties to pulmonary and right ventricle goes to aorta
has to have septal defect or PDA to survive
Aortic arches dev’t: 3-6 becomes the
[Coarctation of the Aorta]
3: common carotids, internal/external carotids
4: also part of subclavian
6: pulmonary artery/ trunks, truncus arterious
Ductus arteriosus is from the:
- 4th pharyngeal arch (left)
Infantile Coarctation
defect in dev’t and regression of the 4th and 6th pharyngeal arch of arteries
