Serologies of Liver Diseases

Question 1

Autoimmune hepatitis type 1

Answer 1

Anti-nuclear antibody (ANA)
Anti-smooth muscle antibody (SMA)
IgG

Question 2

Autoimmune hepatitis type 2

Answer 2

Antibody to liver kidney microsomal antigen-1 (anti-LKM1)
Anti-liver cytosol type 1 (anti-LC1)
IgG

Question 3

Primary biliary cirrhosis

Answer 3

Anti-mitochondrial antibodies (AMA)

Anti-nuclear antibodies (ANA)

Question 4

Primary sclerosing cholangitis

Answer 4

Atypical perinuclear ant-ineutrophil cytoplasmic antibody (p-ANCA)
Also known as per-inuclear antineutrophil nuclear antibodies (p-ANNA)

Question 5

What percentage of patients with autoimmune hepatitis have high IgG (hypergammaglobulinemia)

Answer 5

80%