Sesh 6: Epithelial Tissues, Exocrine Glands And Dermatology Flashcards

(43 cards)

1
Q

What are mucous membranes?

A

They line internal tubes that are open to the exterior & contain mucous-secreting cells.

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2
Q

What are the 3 layers of a mucosal membrane?

A
  1. Epithelium-lines lumen
  2. Lamina propria- connective tissue layer
  3. Muscularis mucosa- in alimentary tract
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3
Q

What are serous membranes?

A

Thin, 2 part-membranes lining closed body cavities.

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4
Q

What are the 2 layers that make up serous membranes?

A
  1. Mesothelium- simple squamous epithelium

2. This connective tissue layer containing blood vessels and nerves

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5
Q

The outer serosal layer surrounding a serous cavity is the ________ serosa, and the inner is the ________ serosa.

A
  1. Parietal

2. Visceral

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6
Q

What is the definition of epithelia?

A

Sheets of contiguous cells of varied embryonic origin that cover the external body surface, and line internal surfaces.

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7
Q

Do epithelia have a blood supply?

A

No, they are avascular.

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8
Q

Give examples of where simple squamous epithelium is found.

A
  • alveoli
  • mesothelium
  • lining of vasculature
  • parietal layer of Bowman’s capsule
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9
Q

Where is simple cuboidal epithelium found?

A
  • thryoid follicles
  • kidney tubule
  • ovary surface
  • small ducts of many exocrine glands
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10
Q

Where is simple columnar epithelium found?

A
  • stomach lining and gastric glands
  • small intestine and colon-villi and microvilli
  • crypts of Lieberkuhn
  • fallopian tubes-ciliated
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11
Q

What is simple pseudostratified epithelium?

A

Looks like more that 1 cell layer, but every cell contacts the basement membrane, even if some do not reach the surface.

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12
Q

Where is non-keratinised, stratified squamous epithelium found?

A
  • Oral cavity
  • Oesophagus
  • Vagina
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13
Q

What are the main functions of non-keratinised, stratified squamous epithelium?

A
  • Protects against abrasion

- Reduces water loss whilst providing moist surface

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14
Q

Give an example of where keratinised, stratified squamous epithelium is found.

A

Epidermis of the skin.

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15
Q

What are the 4 layers of the epidermis of the skin (from apical to basolateral)?

A
  1. Horny layer- stratum corneum
  2. Granular layer
  3. Prickle cell layer
  4. Basal layer- stratum basale
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16
Q

In what layer of the epidermis are melanocytes found?

A

Basal layer

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17
Q

In what epidermis layer does terminal differentiation begin?

A

Prickle cell layer

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18
Q

What is the stratum corneum of the epidermis composed of?

A
  • Flattened corneocytes.

- Almost pure keratin

19
Q

What layer of epidermis contains Langerhans cells?

A

Prickle cell layer

20
Q

Where can transitional, stratified epithelium be found?

A
  • Bladder
  • Ureters (urothelium)
  • Renal calyces
21
Q

Name 2 main functions of transitional, stratified epithelium.

A
  1. Distensibility

2. Protects underlying tissue from toxic chemicals

22
Q

Why do some people have darker/more tanned skin than others?

A

Their melanocytes produce melanosomes, containing the pigment melanin, which last for longer.
*Don’t have more melanocytes.

23
Q

What are glands?

A

Invaginations of epithelium specialised for secretion.

24
Q

What is the name given to the method of secretion of most glands?

A

Merocrine (exocytosis).

25
Give an example of a gland that uses apocrine secretion.
Mammary gland
26
Give an example of a gland that uses holocrine secretion.
Sebaceous gland of skin...whole cell breaks down during secretion.
27
Name the 3 salivary glands.
1. Parotid 2. Sublingual 3. Submandibular
28
List the 7 functions of skin.
1. Protection 2. Sensation 3. Thermal regulation and insulation 4. Excretion and secretion 5. Endocrine 6. Immunity 7. Growth
29
Why are dark-skinned individuals more at risk of Ricket's in temperate climates?
Melanosomes last for longer, meaning they get more UV protection, so are at risk of vit D deficiency--> bone demineralisation.
30
What is the disease characterised by a complete loss of melanocytes?
Albinism
31
What is the dermatological term for redness?
Erythema/rubor
32
What is the dermatological term for heat?
Calor
33
What is the dermatological term for swelling?
Tumor
34
What is the dermatological term for pain?
Dolor
35
What is the dermatological term for loss of function?
Functio laesa
36
What are the 6 signs of inflammation?
1. Redness- rubor 2. Heat- calor 3. Pain- dolor (symptom, not sign) 4. Swelling- tumor 5. Loss of function- functio laesa 6. Itching- pruritus
37
What is lichenification?
Skin thickening with exaggerated skin markings e.g. In eczema on flexors.
38
What areas of skin does eczema mainly affect?
The flexors.
39
What is eczema caused by?
An increased immune reaction to allergens, leading to inflammation of the skin.
40
What is psoriasis caused by?
Hyperproliferation of keratinocytes in skin epidermis...cannot be shed quick enough, leading to lesions. Also get infiltration of leukocytes, leading to inflammation.
41
What surfaces does psoriasis commonly affect?
Extensor surfaces and scalp.
42
What is acne vulgaris?
An inflammatory disease of the pilosebaceous follicle.
43
What are the 2 main causes of acne?
1. Hormonal-androgens | 2. Excess sebum production