Session 12

Question 1

Tobacco related disease is the single biggest cause of

Answer 1

Preventable morbidity and mortality in the NHS

Question 2

What type of addiction is cigarette smoking

Answer 2

Chronic relapsing disorder that starts in adolescence, nicotine causes the addiction, not the harm from tobacco

Question 3

Markers of addiction

Answer 3

Use despite knowledge of harmful consequences
Cravings during abstinence
Failure of attempts to stop
Withdrawal symptoms during abstinence

Question 4

Nicotine physiology

Answer 4

Acts on nicotinic acetylcholine receptor stimulating dopamine release

Satisfaction

Chronic nicotine exposure = ACh upregulated, increases affinity and functional sensitivity to an agonist

Question 5

A drop in nicotine levels leads to

Answer 5

Craving and withdrawal

Question 6

1-2 puffs of a cigarette binds to

Answer 6

50% ACh receptors

Question 7

How long do ACh receptors take to desensitise after the last cigarette

Answer 7

6-12 weeks

Question 8

3As of smoking cessation

Answer 8

Question 9

Pharmacological treatments for smoking cessation

Answer 9

nicotine patches or pills
Nicolette spray
Vaping

Question 10

Advantages of Vaping Vs smoking

Answer 10

Exposure to carcinogens, respiratory related toxicants, and CVD-related toxicants is significantly lower

Question 11

Vaping vs non use

Answer 11

Exposure to carcinogens similar if not higher, exposure to most respiratory related toxicants similar, exposure to CVD-related toxicants similar

Question 12

Features of vaping

Answer 12

Use Vapes for as long as it takes to quit smoking and a low risk of relapse to smoking, then stop vaping

Vaping can be combined with NRT and varenicline to quite smoking

If you dont smoke, dont vape

Vaping is much less harmful than smoking but not risk free

Question 13

Types of stop smoking support and their effectiveness

Answer 13

Question 14

Chance of dying from smoking related disease in smokers

Answer 14

1 in 2