set a quiz Flashcards
(25 cards)
This X-linked disorder is known to have a mutation
in the gene that is responsible for cytoskeletal
remodeling and nuclear transcription in
hematopoietic cells.
a. SCID
b. BTK
c. WAS
d. Chediak Higashi
e. None of the choices
Was
This disorder is an immune dysregulation that
causes the granules found in leukocytes to fuse
and lead to its dysfunction.
a. SCID
b. BTK
c. WAS
d. Chediak Higashi
e. None of the choices
Chediak Higashi
The following describes the nuclei in a patient with
Pelger-Huet Anomaly except:
a. Ovoid
b. Peanut shaped
c. Bilobed
d. Spectacle like
e. None of the choices
None of the choices
This condition causes a degradation of the
substrate sphingomyelin
a. Pelger-Huet
b. May-Hegglin
c. Alder-reily
d. Gaucher
e. Niemann-Pick
Niemann-Pick
This condition is characterized by reactive
neutrophilic leukocytosis
a. Leukocytosis
b. Leukocytopenia
c. Leukemoid Reaction
d. Shift to the left
e. Two of the choices
Leukemoid Reaction
The following is (are) cause(s) of Neutrophilia
except
a. Acute inflammatory
b. Drugs
c. Radiation
d. Neoplastic
e. Two of the choices
Radiation
The following describes toxic granulation except:
a. Peroxidase positive
b. Seen in patients who have received G-CSF
c. Has dark, blue-black granules
d. Seen among lymphocytes
e. None of the choices
Seen among lymphocytes
The image below shows what type of lymphocyte
cell? (circle sya)
a. T art cell
b. Rieder cell
c. Smudge cell
d. LE cell
e. None of the choices
LE cell
The following are characteristics of an acute
hematologic neoplasm except
a. Seen in adults
b. Sudden
c. WBC can be Normal
d. Blasts are usually present
e. Two of the choices
WBC can be Normal
AML that is referred as Naegeli Type Monocytic
Leukemia
a. FAB M3
b. FAB M4
c. FAB M5
d. FAB M6
e. None of the choices
FAB M4
This hematologic condition is characterized by
large heterogenous blasts
a. L1
b. L2
c. L3
d. L4
e. Two of the choices
L2
The following are true regarding Hairy cell
leukemia except
a. Characterized by pancytopenia
b. Cells lack nuclei with ragged projections
c. TRAP resistant
d. Predominantly seen on men in their late age
e. Two of the choices
Two of the choices
- Sezary cells are usually found in what condition?
a. Non-hodgkin’s Lymphoma
b. Mycosis fungoides
c. Hodgkin’s Lymphoma
d. Myedoplastic Syndrome
e. None of the choice
Mycosis fungoides
In Polycythemia vera, a mutation is seen in what
gene?
a. MYC
b. JAK2
c. MYH9
d. T aT
e. None of the choices
JAK2
Positive reaction for MPO stain
a. Blue-black
b. Red-black
c. Blue-Brown
d. Red-Brown
e. None of the choices
Blue-black
Which stain is able to detect lymphocytic cell and
abnormal erythroid by staining glycogen?
a. MPO
b. SBB
c. a-Napthyl Acetate Esterase
d. PAS
e. None of the choices
PAS
What is the purpose of LAP staining?
a. Differentiate myelocytic and monocytic
leukemia
b. Diagnosis of some acute lymphocytic
leukemia
c. Differentiate a myelogenous or monocytic
leukemia from acute lymphocytic leukemia
d. Distinguishing cells of leukemoid reactions
from CML
e. Two of the choices
Distinguishing cells of leukemoid reactions
from CML
What is/are the staining property of Myeloblast in
PAS stain?
a. Positive
b. Negative
c. Diffusely positive
d. Diffusely negative
e. Two of the choices
Two of the choices
Which among the B-cell neoplasms considered as
small lymphocytic lymphoma?
a. CLL
b. Hairy cell leukemia
c. Waldenstom macroglobulinemia
d. Hodgkin’s lymphoma
e. Multiple Myeloma
CLL
The image shown below is known as
(mura syag brain)
a. Histocyte
b. Sezary Cell
c. Reed-Sternberg cells
d. Starry Sky
e. None of the choices
Sezary Cell
At what chromosome is gamma chain deficiency
mutation seen?
a. 20q13.12
b. Xq13.1
c. 1q42.1-2
d. 2q22
e. NOTA
Xq13.1
At what chromosome is WHIM syndrome mutation
seen?
a. 20q13.12
b. Xq13.1
c. 1q42.1-2
d. 2q22
e. NOTA
2q22
A decreased nuclear segmentation is associated
with what gene?
a. Pelger-Huet
b. May-Hegglin
c. Alder-Reily
d. Gaucher
e. Niemann-Pick
Pelger-Huet
Philadelphia chromosome is associated with what
gene?
a. JAK2 V617F
b. NADPH
c. MYC
d. BCR-ABL 1
e. NOTA
BCR-ABL 1
