Seven Transmembrane Repeat Receptors Flashcards

1
Q

Receptor of Thrombin (Ligand)

A

PAR1 and PAR4

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2
Q

Receptor of ADP

A

P2Y1 and P2Y12

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3
Q

Receptor for Thromboxane A2

A

TPa and TP(beta)

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4
Q

Receptor for Epinephrine

A

a2-adrenergic

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5
Q

Receptor for PGI2

A

IP (Inositol Triphosphate)

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6
Q

Receptor for Serotonin

A

5HT 2A

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7
Q

Leads to an increase in intracellular calcium levels and contributes to initial platelet activation, shape change, and the formation of small reversible aggregates

A

P2Y1

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8
Q

Leads to a decrease in cyclic adenosine monophosphate (cAMP) levels and supports the formation of irreversible platelet aggregates

A

P2Y12

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